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Chinese medicine composition for treating prosopalgia and preparation method thereof

A technology of trigeminal neuralgia and composition, applied in the field of medicine, can solve problems such as intolerance to drowsiness, dizziness, severe drug side effects, liver and kidney damage, etc., and achieve comprehensive drug effects, basically non-toxic, and good trigeminal neuralgia Effect

Active Publication Date: 2014-07-02
NANTONG HONGCI PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004]Currently, most western medicines for clinical treatment of trigeminal neuralgia are psychotropic drugs. Carbamazepine is effective for pain relief in 70% of patients, but about 1 / 3 of patients Unable to tolerate side effects such as drowsiness, dizziness, and gastrointestinal discomfort
Sodium phenytoin is not as effective as carbamazepine, but this type of drug is not only easy to become addicted to, but also causes great damage to the liver and kidneys of the body if taken for a long time, and the drug has serious side effects

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Embodiment 1 Chinese medicine composition mixture of the present invention

[0025] Prescription: 15 parts of Angelica dahurica, 15 parts of Atractylodes rhizome, 6 parts of honeysuckle, 10 parts of polygala, 10 parts of jujube seed, 6 parts of wolfberry, 8 parts of acacia bark, 10 parts of Chuanxiong, 20 parts of dandelion, 10 parts of cortex phellodendri, 9 parts of myrrh, frankincense 10 parts, cinnamon 15 parts, licorice 10 parts.

[0026] Preparation method: Take the medicinal materials of the above weight components, add water 5 times the total weight of the medicinal materials, soak for 30 minutes, decoct twice for 2 hours each time, filter, combine the filtrates, and concentrate the filtrates under reduced pressure to a relative density of 1.1 The extract, the relative density is the test result at 60 degrees Celsius, add ethanol until the alcohol content is 75% (v / v), let it stand for 24 hours, take the supernatant, recover the ethanol to concentrate, add water...

Embodiment 2

[0027] Embodiment 2 Chinese medicine composition mixture of the present invention

[0028] Prescription: 15 parts of Angelica dahurica, 15 parts of Atractylodes rhizome, 6 parts of honeysuckle, 10 parts of polygala, 10 parts of jujube seed, 6 parts of wolfberry, 8 parts of acacia bark, 10 parts of Chuanxiong, 20 parts of dandelion, 10 parts of cortex phellodendri, 9 parts of myrrh, frankincense 10 parts, cinnamon 15 parts, licorice 10 parts, white peony 6 parts, mint 12 parts and gallnut 8 parts.

[0029] Preparation method: Take the medicinal materials of the above weight components, add water 5 times the total weight of the medicinal materials, soak for 30 minutes, decoct twice for 2 hours each time, filter, combine the filtrates, and concentrate the filtrates under reduced pressure to a relative density of 1.1 The extract, the relative density is the test result at 60 degrees Celsius, add ethanol until the alcohol content is 75% (v / v), let it stand for 24 hours, take the su...

Embodiment 3

[0030] Embodiment 3 Chinese medicine composition tablet of the present invention

[0031] Prescription: 15 parts of Angelica dahurica, 15 parts of Atractylodes rhizome, 6 parts of honeysuckle, 10 parts of polygala, 10 parts of jujube seed, 6 parts of wolfberry, 8 parts of acacia bark, 10 parts of Chuanxiong, 20 parts of dandelion, 10 parts of cortex phellodendri, 9 parts of myrrh, frankincense 10 parts, cinnamon 15 parts, licorice 10 parts.

[0032] Preparation method: Take each medicinal material of the above weight components, add water 10 times the total weight of the medicinal materials, soak for 60 minutes, decoct once, 1 hour each time, filter, combine the filtrate, and concentrate the filtrate under reduced pressure to a relative density of 1.25 The extract, the relative density is the test result at 60 degrees Celsius, add ethanol until the alcohol content is 80% (v / v), let it stand for 24 hours, take the supernatant, recover the ethanol until concentrated, vacuum dry,...

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Abstract

The invention discloses a traditional Chinese medicine composition for treating trigeminal neuralgia, and relates to the technical field of traditional Chinese medicines. It is prepared from the following raw materials in parts by weight: 15 parts of Angelica dahurica, 15 parts of Atractylodes atractylodes, 6 parts of honeysuckle, 10 parts of polygala, 10 parts of jujube seed, 6 parts of medlar, 8 parts of Albizia juniper, 10 parts of chuanxiong, 20 parts of dandelion, and 10 parts of Cortex Phellodendri 9 parts of myrrh, 10 parts of frankincense, 15 parts of cinnamon, and 10 parts of licorice. The traditional Chinese medicine composition of the invention has good therapeutic effects in treating or preventing trigeminal neuralgia, has low drug side effects, and has significant clinical promotion value.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to a traditional Chinese medicine composition for treating trigeminal neuralgia and a preparation method thereof. Background technique [0002] Trigeminal neuralgia is the most common cranial nerve disease. It is mainly manifested by recurrent paroxysmal severe pain in the distribution area of ​​the trigeminal nerve on one side of the face. The incidence rate in domestic statistics is 52.2 / 100,000. Females are slightly more than males. May increase with age. Trigeminal neuralgia mostly occurs in middle-aged and elderly people, and the right side is more common than the left side. The characteristics of the disease are: in the trigeminal nerve distribution area of ​​the head and face, the onset is sudden, sudden arrest, lightning-like, knife-like, burning-like, intractable, unbearable severe pain. Talking, washing your face, brushing your teeth, or even walking with a gentle bre...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/815A61P25/02
Inventor 梁兆霞
Owner NANTONG HONGCI PHARMA
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