Automatic quantification of asymmetry

A technique of symmetry and objects, applied in the field of diagnosis, which can solve problems such as asymmetry not being evaluated

Active Publication Date: 2013-09-04
KONINKLIJKE PHILIPS ELECTRONICS NV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In existing techniques for analyzing FDG-PET images, asymmetry

Method used

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  • Automatic quantification of asymmetry
  • Automatic quantification of asymmetry
  • Automatic quantification of asymmetry

Examples

Experimental program
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Embodiment Construction

[0020] figure 1 A system 100 for computing an asymmetry index is illustrated. The system 100 includes one or more processors 102 coupled to a functional scanner 104, such as a PET or other nuclear medicine scanner, and a scanner memory 105. In one embodiment, processor memory 106 stores, and processor 102 executes, computer-executable instructions for performing the various functions, methods, techniques, procedures, etc. described herein. The computer-executable instructions are stored as modules in the processor memory 106 . In another embodiment, a series of engines, modules, hardware components, etc. implement the functions described below. The system also includes a display 108 for presenting information to the user.

[0021] The scanner 104 scans an object, such as a brain, to generate functional image data, preferably in the form of a tabulation of received time-stamped data. The image data is stored in the scanner memory 105 .

[0022] A reconstruction unit 110 co...

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Abstract

An apparatus detects asymmetry in an object, such as a brain. The apparatus includes a processor programmed to fit a three-dimensional image of the object to a preselected shape, such as a standard brain atlas. The processor projects the three- dimensional image of the object to a two-dimensional surface image. The processor compares corresponding mirror image symmetric voxel pairs on the left and right sides of the surface image. The processor generates at least one of an asymmetry map and an asymmetry index based on the deviations in the pixel pairs. The processor can also mask, before the comparison, pixels of the surface image which are asymmetric in a normal brain.

Description

technical field [0001] This application relates to the field of diagnostics. It finds particular application in connection with functional imaging of the brain including, but not limited to, positron emission tomography (PET) and single photon emission computed tomography (SPECT) perfusion images. However, it should be appreciated that the described techniques may also be applied to other medical imaging device systems, other anatomical regions, examination of inanimate objects, and the like. Background technique [0002] The human brain is mostly bilaterally symmetric, not only structurally but also metabolically, as measured by [18F]FDG PET imaging. Many subjects with dementia also exhibit symmetrical impairments in brain metabolism. However, many demented subjects exhibit asymmetric brain metabolism, especially early in disease progression. [0003] The determination of asymmetry in the brain has diagnostic value. In some forms of dementia, the affected areas of the b...

Claims

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Application Information

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IPC IPC(8): G06T7/60
CPCG06T7/0014G06T2207/10104G06T2207/30016G06T7/68A61B5/0042
Inventor F·O·蒂勒
Owner KONINKLIJKE PHILIPS ELECTRONICS NV
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