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Traditional Chinese medicine composition for treating diabetes, and preparation method and detection method thereof

A composition and diabetes technology, applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc., can solve problems such as unsatisfactory effects of Chinese patent medicines

Active Publication Date: 2013-12-11
SHAANXI BUCHANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Because of this, an invention patent has been applied for this Chinese medicine composition, its publication number is CN1857618A, and the publication date is November 8, 2006. However, in the actual application process, we found that the effect of the Chinese patent medicine made by the above preparation method is not ideal, and the patent application is to further optimize the preparation process through a large number of experiments, and find a better The preparation process and parameters have been proved to be more effective through clinical pharmacodynamic experiments. Therefore, we have successfully developed a traditional Chinese medicine composition for the treatment of diabetes for the purpose of improving the stability and bioavailability of the preparation.

Method used

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  • Traditional Chinese medicine composition for treating diabetes, and preparation method and detection method thereof
  • Traditional Chinese medicine composition for treating diabetes, and preparation method and detection method thereof
  • Traditional Chinese medicine composition for treating diabetes, and preparation method and detection method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0068] ⑴Anemarrhena 38.1g, ginseng 12.7g, TCS 31.8g, Rehmannia glutinosa 19.1g, Scrophularia scrophulariae 15.2g, Astragalus 25.4g, Adenophora 15.2g, Dendrobium 19.1g, Polygonatum 25.4g, Chinese yam 25.4g, chicken Gold 31.8g is crushed into 80-mesh fine powder, sieved, and set aside;

[0069] (2) Take 31.8g Phellodendron Phellodendron, 12.7g Schisandra Fructus, 19.1g Ligustrum lucidum, and 15.2g Pueraria lobata root, add 8 times the amount of 75% ethanol to reflux and extract twice, each time for 2 hours, filter, combine the filtrate and recover the ethanol until there is no alcohol smell , the medicinal solution is concentrated and dried and crushed into a dry cream powder, sieved, and the medicinal residue is used for later use;

[0070] (3) Combine the medicinal residues in (2) with 15.2g of Ophiopogon japonicus, 38.1g of Digupi 38.1g, and 15.2g of Lycium barbarum, add 10 times the amount of water to decoct twice for 1 hour each time, filter, and combine the filtrate, Conc...

Embodiment 2

[0073] ⑴Anemarrhena 38.1g, ginseng 12.7g, TCS 31.8g, Rehmannia glutinosa 19.1g, Scrophularia scrophulariae 15.2g, Astragalus 25.4g, Adenophora 15.2g, Dendrobium 19.1g, Polygonatum 25.4g, Chinese yam 25.4g, chicken Gold 31.8g is crushed into 60 mesh fine powder, sieved, and set aside;

[0074] (2) Take 31.8g Phellodendron Phellodendron, 12.7g Schisandra Fructus, 19.1g Ligustrum lucidum, and 15.2g Pueraria lobata root, add 7 times the amount of 90% ethanol to reflux and extract 3 times, each time for 1 hour, filter, combine the filtrate and recover the ethanol until it has no alcohol smell , the medicinal solution is concentrated and dried and crushed into a dry cream powder, sieved, and the medicinal residue is used for later use;

[0075] (3) Combine the medicinal residues in (2) with 15.2g of Ophiopogon japonicus, 38.1g of Digupi 38.1g, and 15.2g of Lycium barbarum, add 12 times the amount of water to decoct once, each time for 0.5h, filter, and combine the filtrate , concen...

Embodiment 3

[0078] ⑴Anemarrhena 38.1g, ginseng 12.7g, TCS 31.8g, Rehmannia glutinosa 19.1g, Scrophularia scrophulariae 15.2g, Astragalus 25.4g, Adenophora 15.2g, Dendrobium 19.1g, Polygonatum 25.4g, Chinese yam 25.4g, chicken Gold 31.8g is crushed into 120 mesh fine powder, sieved, and set aside;

[0079] (2) Take 31.8g Phellodendron Phellodendron, 12.7g Schisandra Fructus, 19.1g Ligustrum lucidum, and 15.2g Pueraria lobata root, add 10 times the amount of 60% ethanol to reflux and extract once, each time for 3 hours, filter, combine the filtrate and recover the ethanol until it has no alcohol smell Finally, the medicinal liquid is concentrated and dried and crushed into a dry cream powder, sieved, and the medicinal residue is used for later use;

[0080] (3) Combine the medicinal residues in (2) with 15.2g of Ophiopogon japonicus, 38.1g of Digupi 38.1g, and 15.2g of Lycium barbarum, add 8 times the amount of water to decoct 3 times, each time for 2 hours, filter, and combine the filtrate...

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Abstract

The invention relates to a traditional Chinese medicine composition for treating diabetes, and a preparation method and a detection method thereof. The traditional Chinese medicine composition is prepared by rhizoma anemarrhenae, ginseng, cortex phellodendri, radix trichosanthis, unprocessed rehmannia root, radix scrophulariae and the like. The detection method of the traditional Chinese medicine composition comprises the steps of thin-layer identifications of cortex phellodendri, cortex lycii radicis, fructus lycii, fructus schizandrae, glossy privet fruit and root of kudzu vine; and determination of sarsasapogenin content in the traditional Chinese medicine composition. The traditional Chinese medicine composition provided by the invention has the characteristics of simple and practical process, safety and efficiency, significant pharmacology and drug efficacy and clinical effects.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating diabetes, a preparation method and a detection method thereof, and belongs to the technical field of pharmaceutical preparations. Background technique [0002] In recent years, with the acceleration of the modernization process and the improvement of people's material living standards, the number of diabetic patients at home and abroad is increasing at an alarming rate year by year. Diabetes has been listed as the third largest disease after cardiovascular and tumors. Diabetes mellitus is a systemic disease mainly caused by the disorder of glucose metabolism caused by the absolute or relative deficiency of insulin in the body. The main cause of the disease is the relative or absolute deficiency of insulin. Emaciation is the main feature, and it has the characteristics of high morbidity, many concurrent syndromes, and cannot be cured. At present, there are more than 40 mil...

Claims

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Application Information

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IPC IPC(8): A61K36/8984A61P3/10G01N30/90G01N30/02A61K35/37A61K35/57
Inventor 赵步长赵超
Owner SHAANXI BUCHANG PHARMA
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