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Traditional Chinese medicine granules having effects of invigorating qi and warming yang and preparation method thereof

A technology of traditional Chinese medicine granules and functions, which is applied to medical preparations with non-active ingredients, medical preparations containing active ingredients, and medical formulas, etc. It can solve problems such as large dosage, bad taste, and lack of research and development of Baoyuan Decoction.

Active Publication Date: 2014-01-22
哈尔滨瀚钧现代制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, we have noticed that the current research on Baoyuan Tang focuses on confirmatory research, that is, there is no in-depth research and development on Baoyuan Tang from a new perspective.
The existing Baoyuan Decoction products not only have backward preparation methods, but also have low content of active ingredients, and generally have the problems of large dosage of traditional Chinese medicine and bad taste

Method used

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  • Traditional Chinese medicine granules having effects of invigorating qi and warming yang and preparation method thereof
  • Traditional Chinese medicine granules having effects of invigorating qi and warming yang and preparation method thereof
  • Traditional Chinese medicine granules having effects of invigorating qi and warming yang and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0120] A traditional Chinese medicine granule with the function of invigorating temperature and yang. The raw materials are 5 parts by weight of ginseng, 1 part by weight of astragalus, 3 parts by weight of licorice, and 5 parts by weight of cinnamon. The preparation method includes the following steps:

[0121] (1) Weigh the raw materials in proportion and mix them;

[0122] (2) Add 7 times the weight of distilled water to the bulk drug, and add enzymes, keep the temperature at 40 degrees Celsius, and carry out enzymatic hydrolysis for 2 hours;

[0123] (3) Raise the enzymatically hydrolyzed mixture to 90 degrees Celsius for 8 minutes, after inactivating the enzyme activity, cool to room temperature, filter, and separate filtrate 1 and filter residue 1;

[0124] (4) Take filtrate 1 and centrifuge in a three-foot centrifuge to obtain extract 1;

[0125] (5) Take filter residue 1, and extract the mixed solution of n-butanol-chloroform (1:2) at reflux for 3 hours, and obtain filtrate 2 a...

Embodiment 2

[0131] A traditional Chinese medicine granule with the effect of invigorating temperature and yang, the raw materials are: 4 parts by weight of ginseng, 2 parts by weight of astragalus, 2 parts by weight of licorice, and 7 parts by weight of cinnamon. The preparation method includes the following steps:

[0132] (1) Weigh the raw materials in proportion and mix them;

[0133] (2) Add 6 times the weight of distilled water to the bulk drug, and add enzymes, keep the temperature at 40 degrees Celsius, and perform enzymatic hydrolysis for 3 hours;

[0134] (3) The enzymatically hydrolyzed mixture is heated to 100 degrees Celsius for 5 minutes, after the enzyme activity is inactivated, cooled to room temperature, filtered, and the filtrate 1 and the filter residue 1 are separated;

[0135] (4) Take filtrate 1 and centrifuge in a three-foot centrifuge to obtain extract 1;

[0136] (5) Take the filter residue 1, and extract the mixed solution of n-butanol-chloroform (1:2) under reflux for 4 h...

Embodiment 3

[0142] A traditional Chinese medicine granule with the effect of invigorating temperature and yang, the raw materials are: 6 parts by weight of ginseng, 1 part by weight of astragalus, 2 parts by weight of licorice, and 7 parts by weight of cinnamon. The preparation method includes the following steps:

[0143] (1) Weigh the raw materials in proportion and mix them;

[0144] (2) Add 8 times the weight of distilled water to the bulk drug, and add enzymes, keep the temperature at 40 degrees Celsius, and perform enzymatic hydrolysis for 1 hour;

[0145] (3) The enzymatically hydrolyzed mixture is heated to 80 degrees Celsius for 10 minutes, after the enzyme activity is inactivated, cooled to room temperature, filtered, and the filtrate 1 and the filter residue 1 are separated;

[0146] (4) Take filtrate 1 and centrifuge in a three-foot centrifuge to obtain extract 1;

[0147] (5) Take filter residue 1, and extract the mixed solution of n-butanol-chloroform (1:2) under reflux for 2 hours, ...

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Abstract

The invention relates to traditional Chinese medicine granules having effects of invigorating qi and warming yang. The traditional Chinese medicine granules comprise the raw materials in parts by weight: 1-8 parts of ginseng, 0.5-6 parts of radix astragali, 0.5-6 parts of licorice root, and 2-8 parts of cortex cinnamomi. The invention also provides a preparation method of the traditional Chinese medicine granules. The traditional Chinese medicine granules prepared by the method have outstanding effects of invigorating qi and warming yang. Preliminary pharmacological experiments and clinical application results show that the granules have various efficacies of enhancing body immune function, improving cardiovascular system function, strengthening kidney function and the like. In addition, because of the improvement of the preparation method and matching with proper accessories, the granules are more suitable for industrial mass production, and also have the advantages of convenient taking and good taste because of retention of more active ingredients.

Description

Technical field [0001] The invention belongs to the field of traditional Chinese medicine, and in particular relates to a traditional Chinese medicine granule with the function of replenishing temperature and yang and a preparation method thereof. Background technique [0002] With the increase of life pressure and the acceleration of life speed of modern people, symptoms such as dizziness, dizziness, waist and knee weakness, insomnia and dreaminess caused by body fatigue and qi deficiency are emerging one after another, and the "sub-health" state is common among working people. In the theory of syndrome differentiation in TCM, vitality is the vital energy of the human body, which is stored in the kidneys, and is formed by the qi from the spleen and stomach water and the clear qi inhaled from the lungs; Insufficiency of vitality is one of the common symptoms of traditional Chinese medicine. The main clinical manifestations are qi deficiency and blood deficiency, mental fatigue, l...

Claims

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Application Information

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IPC IPC(8): A61K36/54A61K9/16A61K47/10A61K47/38A61K47/36A61K47/18A61P37/04A61P9/10A61P9/00A61P7/00A61P13/12
Inventor 李细海
Owner 哈尔滨瀚钧现代制药有限公司
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