GnRH (gonadotropin-releasing hormone) castrated vaccine as well as parallel body

Abstract

The invention provides a novel GnRH (gonadotropin-releasing hormone) parallel body as well as a GnRH castrated vaccine on the basis. The GnRH parallel body is structurally characterized in that according to the GnRH parallel body provided by the invention, Cys (cysteine) is not located at the terminal C of an antigen polypeptide sequence, and at least one non Cys amino acid further exists between the Cys and the terminal C. In the parallel body synthetic process, the side reactions are fewer, and a coupled reaction can be well carried out in a carrier protein.

Description

technical field [0001] The present invention relates to a series of GnRH juxtapositions and vaccines made from the juxtapositions, in particular to a series of GnRH juxtapositions easily coupled with carrier proteins and vaccines made from the juxtapositions. Background technique [0002] Surgical castration of most livestock sires, with the exception of breeding sires, has been performed for centuries to reduce feed loss during the fattening phase of the animals due to sexual activity, to reduce injuries and injuries caused by estrus and male aggressive behavior. It can improve the quality of meat (such as the reduction of smell and peculiar smell), and can also make use of the growth characteristics of castrated animals to increase their fat. Therefore, castration is an important technical link in the production process of livestock fattening. [0003] However, since the discovery of the advantages of castration, the castration technique used in animal husbandry has alway...

AI Technical Summary

Problems solved by technology

[0003] However, since the discovery of the advantages of castration, the castration technique used in animal husbandry has always been surgical castration, which is very stressful to animals and generally takes 7-10 days to

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