Sarcandra extract and application thereof

Abstract

The invention discloses a Sarcandra extract and application thereof, belonging to the field of medicine. The Sarcandra extract is prepared by subjecting the whole herb of Sarcandra to water extraction, concentration and drying. 1 g of the Sarcandra extract contains no less than 0.53 mg of isofraxidin (C11H10O5) and no less than 0.38 mg of rosmarinic acid (C18H16O8). The Sarcandra extract provided by the invention has good effects on treatment and prevention of thirst and radioactive dental caries caused by radiotherapy.

Description

technical field [0001] The invention relates to the field of medicine, and relates to an extract derived from the traditional Chinese medicine Jiujie tea and its application. Background technique [0002] Nasopharyngeal carcinoma is one of the most common malignant tumors in my country, and 80% of the world's nasopharyngeal carcinomas occur in China. The incidence of nasopharyngeal carcinoma in Guangxi ranks second only to Guangdong, with an annual incidence of 10-30 per 100,000. According to the data of the fifth national population survey in 2000 (the population of Guangxi is 44.89 million), it is estimated that the nasopharyngeal carcinoma in Guangxi The number of new cases of cancer every year reaches about 10,000 people. According to the third national retrospective survey of causes of death, Cangwu County, Wuzhou City, and Fusui County in Guangxi are counties (cities) with a high incidence of nasopharyngeal cancer in the country, and their nasopharyngeal cancer has ac...

AI Technical Summary

Problems solved by technology

However, limited by the local economy, radiotherapy technology, equipment and the level of practitioners, IMRT is difficult to promote on a large scale. Therefore, the current radiation therapy mode is still dominated by 2DRT, and only a small number of patients receive 3DRT and IMRT.

2DRT has great damage to the function of the parotid gland. Almost all patients with nasopharyngeal carcinoma who receive 2DRT radiotherapy will experience varying degrees of hypofunction or permanent loss of salivary glands, resulting in dry mouth, which will lead to dental caries, fungal infection, loss of taste, difficulty swallowing and talking, A series of complications such as nutritional deficiency seriously affect the quality of life of patients. Therefore, it is an important topic to find ways to solve radiation dry mouth. It is imminent to find ways to effectively reduce the complications of radiotherapy.

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