Human body gastrointestinal tract bionic system and simulation experiment method based on system

A bionic system, gastrointestinal technology, applied in the fields of microbiology, human physiology, nutrition, organic chemistry and analytical testing, bionics, can solve problems such as no feedback mechanism, to eliminate the interference of external factors, good stability Sex, the effect of shortening time

Active Publication Date: 2014-04-23
马爱国 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Despite the complexity of the model, compared with in vivo conditions, existing GI models are still relatively simple, for example, they do not include feedback mechanisms, microbial colonization, immune system, and precise hormone control, etc.

Method used

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  • Human body gastrointestinal tract bionic system and simulation experiment method based on system
  • Human body gastrointestinal tract bionic system and simulation experiment method based on system
  • Human body gastrointestinal tract bionic system and simulation experiment method based on system

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Experimental program
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Effect test

Embodiment 1

[0039] Embodiment 1 The establishment of the human gastrointestinal tract bionic system and the specific process of digestion and absorption are as follows:

[0040] Establishment of human gastrointestinal bionic system: prepare system controller 900 (man-machine interface, data processor module, equipment controller module), data lines 116, 118, digestive juice reagent bottles 200-205, infusion pipelines 111-116 , intestinal flora colonization fermentation tank 305, gastrointestinal tract simulation tank 300-304, magnetic stirrer 400-405, pH meter 800-805, simulated absorber 600-602, gas storage tank 100, gas input pipeline 110, peristaltic Pumps 1-23, constant temperature water tank 306, temperature sensor 806, water pump 500, water delivery pipeline 117, liquid collectors 206-209.

[0041] Connect the digestive juice reagent bottle 200-205 to the peristaltic pump 1-23 through the silicone tube, then connect to the intestinal flora colonization fermentation tank 305 and the ...

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PUM

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Abstract

The invention relates to a human body gastrointestinal tract bionic system and a simulation experiment method based on the system. The system comprises a system controller, an intestinal flora planting system, a simulation digestion system, a simulation absorption system, a stirring system, a rate control system, a gas path system, a temperature adjusting system, a pH adjusting system, a digestion liquid reagent bottle, an absorbing liquid reagent bottle and a collector. The method comprises the following steps: setting parameters of the control system, preparing planting colloidal particles, planting the intestinal flora, simulating digestion and the like. The system simulates gastrointestinal tract digestion, absorption and intestinal microecology of human bodies under in-vitro conditions, is real in simulation and good in reproducibility, and us applicable to study on the fields of nutriology, toxicology, physiology, microbiology and the like as intelligent control is adopted.

Description

technical field [0001] The invention belongs to the technical fields of bionics, human physiology, microbiology, nutrition, organic chemistry and analysis and testing. The invention relates to a bionic system of the human gastrointestinal tract and a simulation test method based on the system, in particular to a method for simulating the digestion and absorption of food in the human gastrointestinal tract and the micro-ecological system of the gastrointestinal tract under in vitro conditions. And a method for simulating digestion, absorption and micro-ecosystem based on the system. Background technique [0002] The human body's digestion and absorption of food is a very complicated process. After food is ingested, it is converted into nutrients for the body to grow. During human digestion, two major processes occur almost simultaneously: (1) the particle size of food is reduced during mechanical transport in the digestive tract; (2) large molecules in food are hydrolyzed in...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12M1/38C12M1/36C12M1/02C12Q1/04
CPCC12M25/16C12M27/02C12M29/00C12M33/00C12M41/12C12M41/26C12M41/42C12M41/48
Inventor 王海松孙进乐国伟施用晖成向荣唐雪
Owner 马爱国
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