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Integrated manufacturing method of a novel composite ligament-bone scaffold

A technology of composite materials and bone scaffolds, applied in the direction of ligaments, scaffolds, prostheses, etc., can solve the problems of stress concentration, ligament graft damage, etc.

Active Publication Date: 2016-07-06
SUSHENG BIOTECH (HAINAN) CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The current ligament grafts are only made of soft ligament materials, and the bone channel is mostly fixed with interface screws, which has the problems of stress concentration and damage to the ligament grafts

Method used

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  • Integrated manufacturing method of a novel composite ligament-bone scaffold
  • Integrated manufacturing method of a novel composite ligament-bone scaffold
  • Integrated manufacturing method of a novel composite ligament-bone scaffold

Examples

Experimental program
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Embodiment Construction

[0019] The present invention will be described in detail below in conjunction with the embodiments and accompanying drawings.

[0020] The process of the integrated manufacturing method of the new composite ligament-bone scaffold is as follows: figure 1 As shown, the negative model of the bone scaffold and the negative mold of the fixation nails are designed by computer, the negative mold of the bone scaffold is generated by Boolean operations, and the negative mold of the bone scaffold and the negative mold of the fixation nails are manufactured by rapid prototyping technology ( figure 1 Middle a).

[0021] Prepare ceramic slurry for the production of bone scaffold. The ceramic slurry is composed of ceramic material β-tricalcium phosphate powder, water solvent deionized water, organic monomer acrylamide, dispersant sodium polyacrylate, crosslinking agent N,N-di Methacrylamide, initiator ammonium persulfate and catalyst N,N,N,N-tetramethylethylenediamine are mixed according t...

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PUM

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Abstract

The invention discloses an integrated manufacturing method of a novel composite ligament-bone scaffold. After a ligament scaffold, a bone scaffold and a fastening nail silicon mold are manufactured, the ligament scaffold and the bone scaffold are connected, a molten fastening nail material is poured into the fastening nail silicon mold, the bone scaffold is pressed into the fastening nail silicon mold, an auxiliary implantation device is placed in a fastening nail material molten liquid which is not solidified and is pulled out after being solidified, and then the ligament-bone scaffold is acquired. The ligament-bone scaffold and an autogenous bone channel are initially fixed through fastening nails, at the later period, an autogenous bone grows into a bone scaffold hole and the bone scaffold is degraded to grow bone tissue, stable physiological fixation is achieved, and the auxiliary implanting device guides the ligament-bone scaffold into the bone channel. The whole ligament-bone scaffold is biodegradable and does not need to be taken out, and the good physiological fixation can be achieved.

Description

technical field [0001] The invention relates to the technical field of biological design and manufacturing of multi-material and multi-structure composite molding, in particular to an integrated manufacturing method of a novel composite material ligament-bone support. Background technique [0002] Ligaments or tendons play a vital role in maintaining the normal movement and stability of humans and animals, but ligament or tendon injuries caused by sports or injuries seriously affect the normal life of people and animals. Clinically, ligament reconstruction surgery is required to restore the normal function of the ligament. The current ligament grafts are simply made of soft ligament materials, and the bone channel is mostly fixed with interface screws, which has the problems of stress concentration and damage to the ligament grafts. Therefore, design and manufacture tissue engineered ligament-bone scaffold, fix the ligament-bone scaffold and autogenous bone at the initial s...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61F2/08A61F2/82A61L27/10A61L27/12A61L27/18A61L27/22
Inventor 张文友李翔贺健康李涤尘
Owner SUSHENG BIOTECH (HAINAN) CO LTD
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