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A composition for treating diabetic nephropathy

A technology of diabetic nephropathy and composition, which is applied in the direction of drug combination, urinary system disease, metabolic disease, etc., and can solve the problems of no unified standard for diagnosis, syndrome type and curative effect judgment, complex clinical symptoms, etc.

Inactive Publication Date: 2018-05-25
青岛山大齐鲁医院(山东大学齐鲁医院(青岛))
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, from the perspective of traditional Chinese medicine, the clinical symptoms of DN are complex, and there is no unified standard for diagnosis, syndrome type and curative effect judgment.

Method used

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  • A composition for treating diabetic nephropathy
  • A composition for treating diabetic nephropathy
  • A composition for treating diabetic nephropathy

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] By weight, take 1g of levocarnitine, 30g of astragalus, 30g of Atractylodes macrocephala, 20g of salvia miltiorrhiza, 20g of cinnamon, 15g of mulberry, 15g of octopus, 15g of safflower, 15g of poria cocos, 15g of forged keel, 15g of forged oyster, and 10g of safflower , Alisma 5g.

[0028] (1) Except for levocarnitine, Chinese medicinal materials are weighed according to the weight ratio of raw materials, and the net selection is carried out;

[0029] (2) mixing and pulverizing the medicinal materials after the above-mentioned net selection into powder, and passing through a 40-mesh sieve to obtain the mixed powder;

[0030] (3) Mix the mixed powder obtained in step (2) with levocarnitine as an active ingredient, mix it with an appropriate amount of starch, sieve it, mix it thoroughly, and divide it into capsules to obtain the product.

Embodiment 2

[0032] By weight, take 0.8g of levocarnitine, 28g of astragalus, 28g of Atractylodes macrocephala, 22g of salvia miltiorrhiza, 18g of cinnamon, 12g of mulberry, 12g of mulberry octopus, 12g of safflower, 12g of poria cocos, 12g of forged keel, 12g of forged oyster, and safflower 8g, Alisma 6g.

[0033] (1) Except for levocarnitine, Chinese medicinal materials are weighed according to the weight ratio of raw materials, and the net selection is carried out;

[0034] (2) Mix the above net-selected medicinal materials, crush them into coarse powder, add 6 times the amount of water, soak for 5 hours, decoct 3 times for 2 hours each time, filter, combine the filtrates, concentrate under reduced pressure to 60°C and heat test A clear paste with a relative density of 1.20-1.25;

[0035] (3) Mix the clear paste obtained in step (2) with levocarnitine as an active ingredient, mix with an appropriate amount of starch, sieve, mix thoroughly, and divide into capsules to obtain.

Embodiment 3

[0037] By weight, take 1g of levocarnitine, 30g of astragalus, 30g of Atractylodes macrocephala, 20g of salvia miltiorrhiza, 20g of cinnamon, 15g of mulberry, 15g of octopus, 15g of safflower, 15g of poria cocos, 15g of forged keel, 15g of forged oyster, and 10g of safflower , Alisma 5g.

[0038](1) Except for levocarnitine, Chinese medicinal materials are weighed according to the weight ratio of raw materials, and the net selection is carried out;

[0039] (2) Mix the above net-selected medicinal materials, crush them into coarse powder, add 8 times the amount of water, soak for 3 hours, decoct twice for 3 hours each time, filter, combine the filtrates, concentrate under reduced pressure to 60°C and heat test A clear paste with a relative density of 1.20-1.25;

[0040] (3) Mix the clear paste obtained in step (2) with levocarnitine as an active ingredient, mix with an appropriate amount of starch, sieve, mix thoroughly, and divide into capsules to obtain.

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Abstract

The invention discloses a composition for treating diabetic nephropathy, wherein the composition is prepared from the following raw medicines: 0.5-1.5g of levocarnitine, 20-40g of astragalus membranaceus, 20-40g of bighead atractylodes rhizome, 10-30g of the root of red-rooted salvia, 10-30g of cortex cinnamomi, 5-25g of parasitic loranthus, 5-25g of ootheca mantidis, 5-25g of flatstem milkvetch seed, 5-25g of poria cocos, 5-25g of forged fossil fragments, 5-25g of forged concha ostreae, 2-15g of red flower and 2-10g of rhizoma alismatis. In use, the composition mainly comprises qi-tonifying medicine, interior-warming medicine, blood-activating blood and stasis-dissolving medicine, heat-clearing medicine, water-disinhibiting and damp-percolating medicine and is supported by western medicine components, so that therapeutic principle and method for tonifying deficiency and tonifying qi, activating blood and dissolving stasis and clearing heat and promoting dieresis are determined; finally, the unexpected technical effect is achieved.

Description

technical field [0001] The invention relates to a composition for treating diabetic nephropathy, in particular to a composition for treating diabetic nephropathy which is compatible with levocarnitine and various raw materials of traditional Chinese medicines. Background technique [0002] With the general improvement of human living standards and the extension of life expectancy, the incidence of diabetes at home and abroad is significantly higher than before. Diabetes has many complications, among which diabetic nephropathy (DN) is one of the most serious and common chronic complications of diabetes, and it is also the main cause of death in diabetic patients. With the improvement of people's living standards, the development of medical and health care, and the aging of society, the prevalence of diabetes is rising at a rapid rate, and diabetic nephropathy has become one of the hotspots and difficulties in the field of medical diabetes research in the world today. [0003...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/884A61K31/205A61P3/10A61P13/12A61K35/02A61K35/618A61K35/64
Inventor 高延霞赵振寰王云霄曹彩霞张伟
Owner 青岛山大齐鲁医院(山东大学齐鲁医院(青岛))