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Drug for treating depression

A technology of depression and medicine, applied in the field of medicine, can solve the problems of high price and large side effects, and achieve the effect of reducing pain, reducing side effects and facilitating recovery

Inactive Publication Date: 2014-05-14
WUXI VISION PRO
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0013] However, most of the existing drugs are expensive and accompanied by relatively large side effects

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] A medicine for treating depression, characterized in that the medicine contains an effective amount of: 4-{4-(4-fluorophenyl)-1-[1-(isoxazol-3-ylmethyl)piper Pyridin-4-yl]-1H-imidazol-5-yl}pyrimidin-2-amine and an effective amount of fluoxetine, the 4-{4-(4-fluorophenyl)-1-[1-(iso The mass ratio of oxazol-3-ylmethyl)piperidin-4-yl]-1H-imidazol-5-yl}pyrimidin-2-amine to fluoxetine is 4:1.

[0023] The preparation process of the drug is a known preparation method in the art, such as blending and granulation.

[0024] Tests by test methods known in the art show that after the patient takes the above-mentioned medicament, the vomiting and sleep disturbance are obviously eliminated, which proves that the side effect of the compound drug for the treatment of depression is obviously eliminated.

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PUM

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Abstract

The invention discloses a drug for treating depression. The drug contains an effective amount of 4-{4-(4-fluorophenyl)-1-[1-(isoxazole-3-ylmethyl)piperidine-4-yl]-1H-imidazole-5-yl}pyrimidine-2-amine and an effective amount of fluoxetine, and the mass ratio of 4-{4-(4-fluorophenyl)-1-[1-(isoxazole-3-ylmethyl)piperidine-4-yl]-1H-imidazole-5-yl}pyrimidine-2-amine to fluoxetine is 3:1 to 6:1. Through combined use of specific drugs, side effects during treatment of depression are greatly reduced, pain of patients is reduced, and recovery of the patients is availed.

Description

technical field [0001] The invention relates to a medicine, in particular to a medicine for treating depression. Background technique [0002] Depression is a common mood disorder, which can be caused by various reasons. The main clinical feature is marked and persistent low mood, and the low mood is not commensurate with the situation. In severe cases, suicidal thoughts and behaviors may appear. Most cases have a tendency to relapse, and most of each attack can be relieved, and some may have residual symptoms or become chronic. [0003] Manic episodes can occur in at least 10% of patients with depression, at which point a diagnosis of bipolar disorder should be made. In addition, the depression we often talk about actually refers to the clinical major depression, and 16% of the population will be affected by it at some point in their lives. In addition to the severe emotional and social costs of suffering from depression, the economic costs are also enormous. According t...

Claims

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Application Information

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IPC IPC(8): A61K31/506A61K31/138A61P25/24
Inventor 廖秀高
Owner WUXI VISION PRO
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