Drug for intervening skin reaction after radiotherapy and preparation method thereof
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A skin reaction and preventive drug technology, applied in skin diseases, drug combinations, pharmaceutical formulations, etc., can solve problems such as no specific method, radiation damage, difficult to heal, etc.
Inactive Publication Date: 2018-06-01
威海市妇女儿童医院
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Problems solved by technology
(3) Grade III reaction: ulceration or necrosis, which invades the dermis, causes radiation damage, and is difficult to heal
[0003] At present, there is no specific method for clinical prevention of skin damage after radiotherapy. Most of them should pay attention to clean and dry local skin.
Method used
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Embodiment 1
[0033] Example 1, the weight ratio of raw materials: 20 parts of Geshanxiao, 10 parts of barley dendrobium, 6 parts of fenugreek vine, 10 parts of Herba chinensis, 6 parts of Haixie, 10 parts of petrel, 10 parts of papaya, 10 parts of magnolia, 10 parts of reed root, 2 parts of scallion, 6 parts of stone gall, 20 parts of yellow gelatin.
[0034] The preparation method of Example 1 is as follows: mix Geshanxiao, barley dendrobium, vine root vine, scorpion grass, sea squid, petrel, papaya, magnolia, reed rhizome, scallion white, stone gallbladder, add water and decoct, and take the filtrate after 30 minutes , adding water to the medicinal dregs and continuing to decoct for 20 minutes, then take the filtrate. After the two filtrates are combined, smelt yellow gelatin and apply local wet compresses for half an hour each time, twice a day.
Embodiment 2
[0035] Example 2, the weight ratio of raw materials: 10 parts of Geshanxiao, 6 parts of barley dendrobium, 3 parts of Miangen vine, 6 parts of Herba chinensis, 3 parts of Hercynidae, 6 parts of Haiyan, 6 parts of Chinese papaya, 6 parts of Magnolia tianmulan, 6 parts of reed root, 1 part of scallion, 3 parts of stone gall, and 10 parts of yellow gelatin.
Embodiment 3
[0036] Example 3, the weight ratio of raw materials: 20 parts of Geshanxiao, 10 parts of barley dendrobium, 6 parts of Mianteng vine, 10 parts of Herba chinensis, 6 parts of Haixie, 10 parts of Haiyan, 10 parts of papaya, 10 parts of Magnolia tianmulan, 10 parts of reed root, 2 parts of scallion, 6 parts of stone gall, 20 parts of yellow gelatin.
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Abstract
The invention discloses a cutireaction intervention medicine after radiotherapy and a preparation method thereof, and aims to solve the problem of prevention of cutireaction after radiotherapy. The preparation method is characterized by comprising the following steps: (1) melting yellow gelatin with a fistular onion stalk decoction to prepare gelatin beads for later use; (2) extracting volatile oil from ivy glorybind herb root and herba siegesbeckiae, collecting, mixing for later use, and taking decoction dregs for later use; (3) carrying out water extraction and alcohol precipitation on Cynachum uilfordii Hemsl, chalcanthite, papaya, Bulbophyllum inconspicuum Maxim, Sargassumthunbergii, petrel, Reed Rhizome, Magnolia amoena and the decoction dregs obtained in the step 1, and taking the supernate; (4) adding the supernate obtained in the step 3 into the gelatin beads obtained in the step 1; addition the mixed volatile oil obtained in the step 2, and evenly mixing to obtain a primary material; and (5) drying the primary material obtained in the step 4, pulverizing, and passing through a 100-mesh screen to obtain the medicinal powder. The clinical experiment proves that the medicine has the characteristics of favorable curative effect and higher safety when being used for preventing cutireaction after radiotherapy, and is worthy of clinical application and popularization.
Description
technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a medicine for intervening skin reaction after radiotherapy and a preparation method thereof. Background technique [0002] Tumor radiation therapy (radiotherapy) is a treatment of malignant tumors by using radiation such as α, β, γ rays produced by radioactive isotopes and x-rays, electron beams, proton beams and other particle beams produced by various x-ray therapy machines or accelerators. method. Radiation injuries of skin are the most common side effects of radiotherapy when a large area is irradiated or irradiated skin folds and moist areas. It is related to the skin's tolerance to radiation, the radiation source used, the irradiated area and the site. Skin reactions are divided into three degrees: ⑴First-degree reactions: erythema, burning and itching sensation, the skin gradually changes from bright red to dark red when the irradiation continues, and there wi...
Claims
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Application Information
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