Formula powder for phenylketonuria children and preparation method thereof

A technology for phenylketonuria and formula powder, which is applied in the field of infant formula milk powder and its preparation, can solve the problems of ineffective intellectual progress and increased burden on kidney filtration, and achieve the effects of simple preparation method, prevention of allergies, and sufficient nutrient absorption

Active Publication Date: 2014-09-03
中恩(天津)医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, it should be combined with diet therapy supplemented with tyrosine to restore hair pigmentation to normal, but it has no effect on mental progress
At present, the special dietary food for patients with phenylketonuria and the glycomacropeptide medicinal food invented by patents CN103462003A and CN102481338A, although there is no phenylalanine, the addition of macromolecular casein glycomacropeptide increases the burden of kidney filtration. Allergic reactions such as diarrhea in children

Method used

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  • Formula powder for phenylketonuria children and preparation method thereof
  • Formula powder for phenylketonuria children and preparation method thereof

Examples

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Comparison scheme
Effect test

Embodiment 1

[0051] A formula powder for children with phenylketonuria, consisting of solid glucose syrup, amino acids, fatty acids, nucleotides, fish oil, dietary fiber, multivitamins, multiminerals and emulsifiers, solid glucose in parts by weight 50 parts of pulp, 15 parts of amino acid, 20 parts of dietary fiber, 22 parts of fatty acid, 0.04 part of nucleotide, 0.15 part of fish oil, 0.5 part of multivitamin, 0.5 part of compound mineral and 0.15 part of emulsifier. The fish oil is composed of DHA and EPA Composition, wherein the weight ratio of DHA and EPA is 4:1; Described emulsifier is soybean lecithin.

[0052] The preparation method of the above formula powder for children with phenylketonuria, the specific preparation steps are as follows:

[0053] (1) Material dissolution and mixing

[0054] Dissolving process:

[0055] Dissolution of water-soluble main ingredients: Weigh solid glucose syrup, amino acids, and dietary fiber according to the formula, add purified water at 50°C t...

Embodiment 2

[0074] A formula powder for children with phenylketonuria, consisting of solid glucose syrup, amino acids, fatty acids, nucleotides, fish oil, dietary fiber, multivitamins, multiminerals and emulsifiers, solid glucose in parts by weight 50 parts of pulp, 10 parts of amino acid, 15 parts of dietary fiber, 20 parts of fatty acid, 0.05 part of nucleotide, 0.05 part of fish oil, 0.75 part of multivitamin, 0.1 part of compound mineral and 0.2 part of emulsifier. The fish oil is composed of DHA and EPA Composition, wherein the weight ratio of DHA and EPA is 5:1; The emulsifier is diglycerin fatty acid citrate.

[0075] The preparation method of the above formula powder for children with phenylketonuria, the specific preparation steps are as follows:

[0076] (1) Material dissolution and mixing

[0077] Dissolving process:

[0078] Dissolution of water-soluble main ingredients: Weigh solid glucose syrup, amino acids, and dietary fiber according to the formula, add 30°C purified wat...

Embodiment 3

[0095] A formula powder for children with phenylketonuria, consisting of solid glucose syrup, amino acids, fatty acids, nucleotides, fish oil, dietary fiber, multivitamins, multiminerals and emulsifiers, solid glucose in parts by weight 55 parts of pulp, 15 parts of amino acid, 3 parts of dietary fiber, 25 parts of fatty acid, 0.01 part of nucleotide, 0.2 part of fish oil, 0.25 part of multi-vitamin, 0.8 part of multi-mineral and 0.05 part of emulsifier. The fish oil consists of DHA, EPA , lecithin, BH4, ARA, dopamine, serotonin and taurine, the weight ratio is DHA: EPA: lecithin: BH4: ARA: dopamine: serotonin: taurine = 4:1:0.2:0.3:0.1 :0.1:0.2:0.15; the emulsifier is monoglyceride fatty acid citrate.

[0096] The preparation method of the above formula powder for children with phenylketonuria, the specific preparation steps are as follows:

[0097] (1) Material dissolution and mixing

[0098] Dissolving process:

[0099] Dissolution of water-soluble main ingredients: Weig...

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Abstract

The invention provides formula powder for phenylketonuria children and a preparation method thereof. The formula powder comprises solid glucose syrup, amino acid, fatty acid, nucleotide, fish oil, dietary fiber, composite vitamins, composite mineral substances and an emulsifier, and is prepared by using a wet-method preparation process of materials. According to the formula powder, special free amino acid is adopted, a proper amount of free L-tyrosine is screened and optimized, and phenylalanine is removed, so that the physiological needs of sick children are met, and at the same time hypersensitivity of phenylketonuria infants is effectively prevented; in the formula, the components have the mutual synergistic effect, the powder is approximate to breast milk in absorption, taste and the like, children can absorb sufficient nutrition after taking the powder, and meanwhile anaphylaxis such as diarrhea can be effectively reduced; and the formula powder is simple in preparation method and applicable to requirements of large-scale industrial production.

Description

technical field [0001] The invention relates to an infant formula milk powder and a preparation method thereof, in particular to a formula powder for children with phenylketonuria and a preparation method thereof. Background technique [0002] Phenylketonuria, the English name is Phenylketonuria, referred to as PKU, is a genetic disease, as early as the 1930s, there were related reports, newborns manifested after 3 to 6 months of feeding, can lead to neurological abnormalities, excitement and restlessness , drowsiness, lethargy, decreased muscle tension, hair and skin lightening caused by lack of melanin, and urine and sweat have a special mouse urine odor. If untreated or not treated in time, children often die in early childhood. In 1934, Dr. Folling of Norway used FeCL3 to test the urine of children and found that the concentration of alanine in the patient's blood was elevated, so he named the disease phenylketonuria; in 1947, Dr. Jervis found that PKU patients could not...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23C9/158A23C9/152A23C9/16
Inventor 吴乐斌刘汉民胡晨旭
Owner 中恩(天津)医药科技有限公司
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