The invention discloses a modified attapulgite-containing mulberry fertilizer and a preparation method thereof. The modified attapulgite-containing mulberry fertilizer comprises raw materials in parts by weight: 34-37 of urea, 25-28 of livestock manure, 15-18 of weathered coal, 1-2 of ferrous sulfate, 0.4-0.6 of ammonium molybdate, 0.5-0.8 of potassium chloride, 1.4-1.6 of magnesium sulfate, 1-3 of humic acid, 1.5-2.5 of trace element fertilizer, 4-5 of modified attapulgite, 6-8 of titanium dioxide, 0.8-1.2 of sodium dodecyl sulfate, 0.7-1.0 of sodium carboxymethyl cellulose, 2-3 of polyoxylethylene ether type acrylic ester, 1-3 of citric acid, 4-6 of colza oil, 1-3 of propylene glycol, and 9-11 of diatomaceous earth. The fertilizer takes urea, livestock manure and weathered coal as main raw materials, so that the mulberry is flourishing in roots, vigorous to grow, easy to plant, easy to manage, and long in service life; the water and soil loss can be reduced, and the ecological environment construction quality can be improved; and the modified attapulgite and titanium dioxide are added in the raw materials as stuffing, so that the adsorption structure is added, the blocking can be prevented, and the dispersity is increased.