Elastic wall surface micro-fluidic chip based on T-shaped micro-channel

Abstract

The invention discloses a micro-fluidic chip for generating micro-droplets the sizes of which are uniform, and belongs to the technical field of experimental devices and methods. The elastic bottom surface T-shaped micro-fluidic chip mainly comprises a dispersed phase inlet, a side channel, a continuous phase inlet, a main channel, an outlet, a main solid structure, a film bottom surface structure, a base and a glass slide. Two incompatible liquids for generating the micro-droplets can flow in from the dispersed phase inlet and the continuous phase inlet and are joined on a joint of the side channel and the main channel, a dispersed phase breaks to form the droplets which can flow to the downstream along with a continuous phase and finally flow out of the chip through the outlet; the film bottom surface structure deforms and vibrates under the liquid action, a droplet generation process is influenced, and the micro-droplets with good uniformity are obtained. The micro-fluidic chip provided by the invention can utilize a simple T-shaped micro-channel structure to generate micro-scale droplets with good uniformity, which cannot be generated by a general T-shaped micro-fluidic chip, without an extra driving or control device, the micro-fluidic chip is intuitive and distinct, and the operation is simple.

Description

technical field [0001] The invention relates to a method for generating microdroplets based on T-shaped microchannels. Through the use of a simple auxiliary structure, the efficiency of emulsified microdroplets in T-shaped microchannels can be significantly improved without applying additional driving devices and control devices. Uniformity in size, thereby improving the reliability of emulsified droplets in their respective applications. Background technique [0002] With the vigorous development of small-scale chemical or biological analysis systems, various types of microfluidic devices involving micro total analysis ayatems (μTAS) or lab-on-a-chip (lab-on-a-chip) are widely used. Design and research, the research on micro-scale flow has obtained relatively rich results, and on this basis, some generally recognized flow structures for different applications have been formed. [0003] The high development of micro-scale manufacturing technology at this stage also provides...

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Problems solved by technology

[0005] Although on the basis of micro-scale flow theory and the development of microfluidic technology, the research on micro-droplets has achieved many results that are widely accepted by researchers, but for the inhomogeneity and control of the droplet generation process Issues such as the method of its inhomogeneity are less involved

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