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Cosmetic or dermatological composition comprising alkyl pentoside vesicles and process for its preparation

A kind of alkyl pentoside, dermatological technology, applied in the field of preparation of the composition, can solve problems such as crystallization over time

Active Publication Date: 2019-02-22
LVMH RECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0009] However, the Applicant has been able to observe that certain alkylpentanosides have the disadvantage of crystallizing over time when dispersed in cosmetic or dermatological compositions having an aqueous continuous phase

Method used

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  • Cosmetic or dermatological composition comprising alkyl pentoside vesicles and process for its preparation
  • Cosmetic or dermatological composition comprising alkyl pentoside vesicles and process for its preparation
  • Cosmetic or dermatological composition comprising alkyl pentoside vesicles and process for its preparation

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Embodiment approach

[0049] According to another preferred embodiment, the mass ratio of [alkyl pentoside / sorbitan monolaurate] is 2-4.

[0050] The present inventors have demonstrated that, once applied to the body or facial skin, the composition according to the present invention significantly improves the skin penetration of active agents encapsulated within vesicles dispersed in the composition.

[0051] Thus, the present invention is particularly useful for encapsulating active agents in the field of cosmetics and dermatology.

[0052] Thus, the cosmetically or dermatologically active agent is at least partially encapsulated in vesicles dispersed in the aqueous phase of the composition according to the invention.

[0053] These vesicles may contain an aqueous or non-aqueous phase that may contain one or more dissolved or dispersed active agent.

[0054] The composition according to the invention comprises at least one cosmetic or dermatological active agent, which may be in the form of puri...

Embodiment 1

[0090] Embodiment 1: Aqueous composition of the present invention

[0091] preparation

[0092] The preparation of octyldecylxylan using D-xylose and an excess of fatty alcohol mixture according to methods known to those skilled in the art, such as in example 1 and The method described in 2.

[0093] D-xylose is placed in contact with a fatty alcohol mixture in an acidic medium, the fatty alcohol mixture comprising 1-decanol (the first fatty alcohol, C10) and 1-octanol (the second fatty alcohol, C8), [ The mass ratio of C10 / C8] is 90 / 10.

[0094]The resulting xylans, denoted (C8 / C10) alkyl xylans, were used in the compositions of this example, and in comparative examples 2.1-2.3.

[0095] The preparation conditions were adjusted so that the degree of polymerization of the octyldecylxylan was about 1.5.

[0096] Compositions in the form of hydrogels were prepared with the following compositions (percentages are given on a weight basis).

[0097] Phase A

[0098] Caffeine ...

Embodiment 2

[0138] Example 2: Stability Study

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Abstract

The present invention also relates to a process for preparing the composition, which consists in placing a mixture comprising alkyl polypentoside, the surfactant and the alcohol in contact with an aqueous phase with stirring.

Description

technical field [0001] The present invention relates to a cosmetic or dermatological composition comprising an alcohol, a surfactant and an alkylpentanoside. The invention also relates to a process for preparing the composition. Background technique [0002] Alkyl polyglycosides are amphiphilic molecules formed by grafting a hydrophilic moiety (composed of sugars) to a lipophilic moiety (composed of alkyl groups). These compounds can form vesicles in the aqueous phase under certain conditions. [0003] Document DE 19634374-A1 describes vesicle dispersions formed by alkyl polyglycosides (APG for short) of formula (1): [0004] RO(G) n (1) [0005] Wherein, R is a straight-chain aliphatic group containing 12-22 carbon atoms, G represents sugar or oligoside, and the polymerization degree n of the sugar is 1-2. These vesicles are prepared from a mixture of sugars or oligosaccharides (product A) and straight-chain fatty alcohols with 12-22 carbon atoms (product B) at an A / B...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/60
CPCA61K8/14A61K8/34A61K8/4973A61K8/604A61P17/00A61Q19/00A61K8/602
Inventor 安热利克·皮乔特瓦莱里·阿拉尔蒂埃里·普热多米尼克·斯卡特瑞里锡德里克·埃尔内文鲍里斯·埃斯特林
Owner LVMH RECH
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