Dendrobium candidum compound preparation and preparation method thereof

A compound preparation and technology of Dendrobium officinale are applied in the field of compound preparations of Dendrobium officinale and its preparation to achieve the effects of improving mental state, improving sleep quality and restoring physical state

Inactive Publication Date: 2014-11-19
KUNMING INST OF BOTANY - CHINESE ACAD OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, the research and development of the compound preparation of Dendrobium candidum is mainly on the use of the immune enhancement effect of Dendrobium candidum polysaccharides, and it is mostly used in combination with American ginseng to enhance human immunity. Report on the Compound Preparation That Stimulates Human Immunity

Method used

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  • Dendrobium candidum compound preparation and preparation method thereof
  • Dendrobium candidum compound preparation and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0032] Dendrobium officinale: 150 grams; Gastrodia elata: 80 grams; Baiziren: 60 grams; Suanzaoren: 100 grams; Shouwu vine: 60 grams; Lycium barbarum: 100 grams. The above 6 flavors are decocted twice with water, the first time is 2 hours, the second time is 1.5 hours, the decoction is filtered, combined and concentrated to obtain 204.1 grams of extract, and the extraction rate is 38.51%.

[0033] Get 10 grams of the obtained extract, dissolve with 50 milliliters of 40% ethanol, add 5 grams of lactose, 2.5 grams of mannose, and 80 grams of soluble starch, wet granulate with a 20-mesh sieve, dry and shape, and pass through a 20-mesh sieve to obtain 90 granules. gram.

Embodiment 2

[0035] Dendrobium candidum: 600 grams; Gastrodia elata: 300 grams; Baiziren: 180 grams; Suanzaoren: 100 grams; Shouwu vine: 180 grams; Lycium barbarum: 100 grams.

[0036] Take the above 6 traditional Chinese medicine powders, add water and decoct twice. Add 12 times the amount of water for the first time, decoct for 3 hours; add 10 times the amount of water for the second time, decoct for 2 hours, combine the two decoctions, settle for 24 hours, filter, take the filtrate, and concentrate under reduced pressure to a relative density of 1.20 ~1.28 (60°C), slowly add ethanol under stirring to make the alcohol content 50%, cool down for 24 hours, filter, take the filtrate and concentrate under reduced pressure to a thick paste with a relative density above 1.35 (80°C), dry under reduced pressure, and crush into fine powder (through a 100-mesh sieve), get the fine powder and add the prescribed amount of propylene glycol and PEG 400, mix evenly, and pack into capsules to obtain 100...

Embodiment 3

[0038] Dendrobium candidum: 600 grams; Gastrodia elata: 300 grams; Baiziren: 180 grams; Suanzaoren: 100 grams; Shouwu vine: 180 grams; Lycium barbarum: 100 grams.

[0039] Take the above 6 traditional Chinese medicine powders, extract twice with 70% ethanol under reflux, each time for 2 hours, filter, recover the ethanol from the filtrate and concentrate it to an extract with a relative density of 1.20 for later use; decoct the residue twice, the first time for 2 hours, the second time After 1.5 hours, the decoctions were combined and concentrated to an extract with a relative density of 1.2 for later use. Put an appropriate amount of starch and dextrin in a suitable container, add hot extract, stir quickly and evenly to make a soft material, and make wet granules in a swinging granulator, spread the granules in a suitable container (for drying), and dry The temperature is 60°C. During the drying process, the granules should be turned in time. The dried granules are sieved and...

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Abstract

The invention provides a dendrobium candidum compound preparation, a preparation method thereof, and an application thereof in preparation of drugs or health-caring products for promoting sleep. The compound preparation is composed with dendrobium candidum and gastrodia elata as main components matched with medicines comprising platycladi seeds, spina date seeds, caulis polygoni multiflori, fructus lycii and the like. The main components and the medicines are parepared into a powder, an extract or a preparation which is prepared with addition of pharmaceutically acceptable auxiliary materials or auxiliary ingredients. The dendrobium candidum compound preparation can effectively promote sleep, can improve sleep status, can enhance immunity, is definite in curative effects, is free of addiction and dependence and is free of toxic and side effects.

Description

Technical field: [0001] The invention belongs to the technical field of medicine preparation. Specifically, the present invention relates to a compound preparation of dendrobium officinale and a preparation method thereof. Background technique: [0002] Sleep disorders and even insomnia are common diseases in the modern population, and it is a subjective experience that affects daily work and life due to dissatisfaction with sleep time or sleep quality. Sleep disorders can be short-term or long-term. With the acceleration of the social rhythm and the increase of mental pressure, the incidence of sleep disorders is on the rise. Long-term sleep disorders will affect people's brain function and blood pressure, requiring drug conditioning and health care intervention. At the same time, sleep also plays a very important role in the immunity of the human body. Studies have shown that those who are deprived of sleep have a significantly lower NK cell value and lower immunity; peo...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8988A23L1/29A61P25/20A61P37/04A23L33/00
Inventor 胡江苗杨柳徐顶巧高巍董发武周俊刘玉清
Owner KUNMING INST OF BOTANY - CHINESE ACAD OF SCI
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