Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

A kind of sugar-lowering and sugar-stabilizing yeast powder and its preparation method and application

A yeast, yeast expression technology, applied in fungi, pharmaceutical formulations, medical preparations containing active ingredients, etc., can solve problems such as poor control of dosage and low blood sugar reaction, and achieve easy large-scale production. Blood sugar, high safety effect

Inactive Publication Date: 2017-08-25
XIAN GUOYU BIOTECH
View PDF3 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the side effects of the drug include gastrointestinal reactions; and the dosage is not easy to control, and hypoglycemia reactions are prone to occur after taking it, and glucose will be administered orally or intravenously

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A kind of sugar-lowering and sugar-stabilizing yeast powder and its preparation method and application
  • A kind of sugar-lowering and sugar-stabilizing yeast powder and its preparation method and application
  • A kind of sugar-lowering and sugar-stabilizing yeast powder and its preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0045] The present invention will be further described in detail below in conjunction with specific embodiments, which are explanations of the present invention rather than limitations.

[0046] In order to overcome the single action mechanism of current diabetes drugs, the present invention considers all aspects of pancreatic islet cell repair, insulin-stimulated release, insulin sensitization, and direct action of insulin, and utilizes genetic technology to construct yeast expressing recombinant GLP-1 analogues, and In order to solve the shortcoming that natural GLP-1 is easily degraded by dipeptidyl peptidase Ⅳ (DPP-Ⅳ) in the body, and its plasma half-life is less than 2 minutes, the recognition site for DPP-Ⅳ to degrade GLP-1 is at the second amino acid A, change it to G, which is not recognized by enzymes, to prolong the half-life without affecting biological activity. The yeast is expressed with the recombinant gene, and the inorganic chromium, inorganic selenium and ino...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses yeast powder for reducing and stabilizing blood sugar as well as a preparation method and application of the yeast powder. The yeast is expressed as GLP-1, and contains a glucose tolerance factor, selenium yeast and vanadium yeast converted by inorganic chromium, inorganic selenium and inorganic vanadium. According to the yeast powder disclosed by the invention, islet cells are promoted to secrete insulin through glucagon-like peptide-1; through the glucose tolerance factor, insulin resistance is reduced and insulin sensitivity is enhanced; and through the organic selenium yeast, repairing of the islet cells is promoted. From islet cell repairing and insulin releasing to insulin sensitizing, the organic vanadium directly serves as para-insulin and comprehensively treats pathogen of type II diabetes, and an effect is much better than that of a single treatment scheme; moreover, multiple efficacy factors are prepared through single yeast powder production; the yeast powder is easy for mass production, low in cost, and more economical and applicable.

Description

technical field [0001] The invention belongs to the technical field of diabetes prevention and treatment, and relates to a sugar-lowering and sugar-stabilizing yeast powder and a preparation method and application thereof. Background technique [0002] Diabetes has been listed as the third biggest killer after cardiovascular and cerebrovascular diseases and tumors. With changes in lifestyle and diet, the global prevalence of diabetes is on the rise. It is estimated that by 2030, the number of people with diabetes in the world will increase to 366 million, and diabetes will become a heavy burden for many families and society. [0003] The etiology of type II diabetes patients is multifaceted. Some patients are due to insufficient insulin secretion, but some diabetics not only do not lack insulin in their bodies but are higher than normal. The cause is insensitivity to insulin (insulin resistance). The vast majority of people with type 2 diabetes will inevitably be treated w...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): C12N1/16A61P3/10A61K33/04A61K33/24
CPCA61K33/04A61K33/24A61K36/064A61K2236/19A61K2300/00
Inventor 李元师长宏赵金礼张明杰
Owner XIAN GUOYU BIOTECH
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com