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A traditional Chinese medicine composition for treating dry eye and preparation method thereof

A dry eye syndrome and composition technology, which is applied in the field of traditional Chinese medicine composition for treating dry eye syndrome and its preparation, can solve the problems of short local therapeutic action time, unfavorable disease control, short action time, etc. Effects of carrying, saving medicinal materials, and improving subjective symptoms

Active Publication Date: 2020-11-06
HUNAN UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are many modern medical treatment methods, mainly using artificial tears, anti-inflammatory and immune preparations, etc. Although the local treatment method can alleviate the patient's subjective symptoms to a certain extent, the effect time is not long. Once the drug is stopped, it is easy to relapse, and it is difficult to recover fundamentally solve the problem
Some artificial tears contain preservatives, stabilizers and other additives, long-term use of patients will cause damage to the ocular surface
[0004] At present, the treatment of dry eye syndrome mostly adopts topical treatment, but local treatment is short-acting, it is difficult to solve the problem fundamentally, and local medicine often contains additives such as preservatives, long-term use will cause damage to the ocular surface
detrimental to disease control

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032]Rehmannia glutinosa 15g, angelica 10g, wolfberry fruit 15g, sand ginseng 20g, white peony root 10g, dendrobium 15g, sealwort 20g, moutan cortex 10g, chrysanthemum 10g, astragalus 20g and licorice 6g were respectively crushed into coarse powder, mixed, and decocted twice For the first time, add 10 times the amount of water, decoct for two hours, and filter; add 8 times the amount of water for the second time, decoct for two hours, and filter; combine the filtrates, concentrate under reduced pressure to remove water, and obtain a dry paste, which is crushed into For fine powder, spray the obtained fine powder and sterilized cold boiled water continuously and uniformly according to the mass ratio of 2:1, add them to the mixer and mix them evenly to form a semi-moist mixture with a certain viscosity, and then squeeze the obtained mixture through a refining machine Pressing, pressing, and kneading are more evenly mixed, and the mixed material is extruded by the pressing plate ...

Embodiment 2

[0034] Rehmannia glutinosa 10g, angelica 5g, medlar 10g, sand ginseng 15g, white peony root 5g, dendrobium 10g, sealwort 15g, moutan cortex 5g, chrysanthemum 5g, astragalus 15g and licorice 3g were respectively crushed into coarse powder, mixed, and decocted twice For the first time, add 10 times the amount of water, decoct for two hours, and filter; add 8 times the amount of water for the second time, decoct for two hours, and filter; combine the filtrates, concentrate under reduced pressure to remove water, and obtain a dry paste, which is crushed into For fine powder, spray the obtained fine powder and sterilized cold boiled water continuously and uniformly according to the mass ratio of 2:1, add them to the mixer and mix them evenly to form a semi-moist mixture with a certain viscosity, and then squeeze the obtained mixture through a refining machine Pressing, pressing, and kneading are more evenly mixed, and the mixed material is extruded by the pressing plate of the refin...

Embodiment 3

[0036] Rehmannia glutinosa 20g, angelica 15g, wolfberry fruit 20g, sand ginseng 25g, white peony root 15g, dendrobium 20g, sealwort 25g, moutan cortex 15g, chrysanthemum 15g, astragalus 25g and licorice 9g were crushed into coarse powder, mixed, decocted twice For the first time, add 10 times the amount of water, decoct for two hours, and filter; add 8 times the amount of water for the second time, decoct for two hours, and filter; combine the filtrates, concentrate under reduced pressure to remove water, and obtain a dry paste, which is crushed into For fine powder, spray the obtained fine powder and sterilized cold boiled water continuously and uniformly according to the mass ratio of 2:1, add them to the mixer and mix them evenly to form a semi-moist mixture with a certain viscosity, and then squeeze the obtained mixture through a refining machine Pressing, pressing, and kneading are more evenly mixed, and the mixed material is extruded by the pressing plate of the refining ...

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PUM

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Abstract

The invention discloses a traditional Chinese medicine composition for treating xerophthalmia. The traditional Chinese medicine composition for treating xerophthalmia is prepared from the following substances in parts by weight: 10-20 parts of dried rehamnnia roots, 5-15 parts of Chinese angelica, 10-20 parts of fruits of Chinese wolfberry, 15-25 parts of roots of straight ladybell, 5-15 parts of white peony roots, 10-20 parts of dendrobe, 15-25 parts of rhizoma polygonati, 5-15 parts of moutan barks, 5-15 parts of chrysanthemum flowers, 15-25 parts of radix astragali and 3-9 parts of licorice root. The invention aims at providing a traditional Chinese medicine composition which is safe and effective for treating xerophthalmia, and also aims at providing a preparation method of the traditional Chinese medicine composition for treating xerophthalmia. The preparation method is simple to operate, easy to implement and capable of effectively extracting and keeping active ingredients in the Chinese herbal medicines to the greatest extent.

Description

technical field [0001] The invention relates to the field of medicines and health care products, in particular to a traditional Chinese medicine composition for treating dry eye and a preparation method thereof. Background technique [0002] Dry eye syndrome, also known as keratoconjunctival dryness or tear insufficiency syndrome, refers to the tear film stability decrease caused by abnormal tear quality and quantity or abnormal dynamics, accompanied by eye discomfort, leading to ocular surface tissue lesions. It is a general term for diseases and is one of the most common ophthalmic diseases at present. The disease is more common in middle-aged and elderly people, and seriously affects the quality of life of patients. With the acceleration of the pace of human life, problems such as dry climate, air pollution, and aging population are becoming more and more serious, the popularity of high-tech products and the wide application of contact lenses, the incidence of dry eye sy...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8984A61P27/02
CPCA61K9/16A61K36/23A61K36/232A61K36/287A61K36/34A61K36/342A61K36/481A61K36/484A61K36/71A61K36/804A61K36/815A61K36/8969A61K36/8984A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 李点
Owner HUNAN UNIV OF CHINESE MEDICINE
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