Senecio scandens Buch.-Ham injection as well as preparation method and application thereof

A Senecio and injection technology, applied in the direction of medical formula, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc., to achieve the effect of low cost, simple operation, and good bactericidal effect

Inactive Publication Date: 2015-04-01
GUANGDONG OCEAN UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In terms of botany, pharmacology and toxicology, Senecio is different from other plants of the genus Senecio. Folks use Senecio to treat skin eczema, boils, typhoid fever, bacillary dysentery, lobar pneumonia, red eyes and swelling, killing Insects, itching and other diseases, but it is rare to use Senecio as a veterinary drug to treat animal diseases

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Senecio 60% ethanol extract is prepared by the following method: take Senecio medicinal material, add pure water for reflux extraction at 100°C for 3 hours, filter, take the filter residue and dry it, add 60% ethanol and 90°C reflux extraction for 3 hours, twice , filtered, combined filtrates, and concentrated at 80° C. for 3 hours to obtain Senecio 60% ethanol extract; add 10 milliliters of purified water to every gram of Senecio medicinal material, and add 10 milliliters of 60% ethanol to every gram of Senecio medicinal material.

[0024] Stir 3% Senecio 60% ethanol extract, 0.1% yellow amine synergist TMP, 8% ethylene glycol, 0.1% polysorbate, 0.05% benzyl alcohol, and water for injection to form a suspension; another 0.2% Citrate was added to the suspension, stirred while adding, and finally water for injection was added to the prescribed amount, stirred evenly, finely filtered, and Senecio injection was obtained.

Embodiment 2

[0026] The 60% ethanol extract of Senecio is prepared by the following method: take the Senecio medicinal material, add pure water for reflux extraction at 100°C for 2 hours, filter, take the filter residue and dry it, add 60% ethanol for 2 hours and 3 times at 90°C for reflux extraction , filtered, combined filtrates, concentrated at 70° C. for 3 hours to obtain Senecio 60% ethanol extract; 8 milliliters of purified water was added to every gram of Senecio medicinal material, and 8 milliliters of 60% ethanol was added to every gram of Senecio medicinal material.

[0027] The preparation method of Senecio injection comprises the following steps: stirring 10% Senecio 60% ethanol extract, 0.5% yellow amine synergist TMP, 20% propylene glycol, 0.5% glycerin, 0.50% benzalkonium chloride, and water for injection Uniformly form a suspension; add another 0.6% tartrate to the above suspension, stir while adding, and finally add water for injection to the prescribed amount, stir evenly,...

Embodiment 3

[0029] The 60% ethanol extract of Senecio is prepared by the following method: take Senecio medicinal material, add pure water to carry out reflux extraction at 100°C for 3 hours, filter, take the filter residue and dry it, add 60% ethanol and reflux extraction at 100°C for 2 hours, twice , filtered, combined filtrates, and concentrated at 80° C. for 2 hours to obtain Senecio 60% ethanol extract; add 7 milliliters of purified water to every gram of Senecio medicinal material, and add 7 milliliters of 60% ethanol to every gram of Senecio medicinal material.

[0030] The preparation method of Senecio injection comprises the following steps: stirring 5% Senecio 60% ethanol extract, 0.3% yellow amine synergist TMP, 10% glycerol, 0.3% glycerin, 0.30% citric acid, and water for injection Uniformly form a suspension; add another 0.4% phosphate to the above suspension, stir while adding, and finally add water for injection to the prescribed amount, stir evenly, and finely filter to obt...

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Abstract

The invention relates to the technical field of injections for animals, in particular to a senecio scandens Buch.-Ham injection as well as a preparation method and an application thereof. The senecio scandens Buch.-Ham injection comprises senecio scandens Buch.-Ham extract which is 60% ethanol extract from senecio scandens Buch.-Ham. The 60% ethanol extract from senecio scandens Buch.-Ham is adopted as an effective part to prepare the senecio scandens Buch.-Ham injection, the operation is simple, the cost is lower, and the senecio scandens Buch.-Ham injection can be applied to industrial mass production; and the prepared senecio scandens Buch.-Ham injection has good sterilization efficacy and has good effect in the aspect of respiratory and digestive mixed bacterial infection control, and the effective treatment rate of the senecio scandens Buch.-Ham injection is up to 93%.

Description

technical field [0001] The invention relates to the technical field of veterinary injections, in particular to a Senecio injection and its preparation method and application. Background technique [0002] Senecio (Sonecio scandens Buch.-Ham.) is a perennial climbing herb of the genus Senecio in the Compositae family, also known as Jiuliming, Yishaoguang, Qianliji, etc. The whole herb is used as medicine, which has the effects of clearing heat and detoxifying, clearing liver and improving eyesight, removing putrefaction and promoting muscle growth, killing insects and relieving itching, and can cure rheumatism, bone pain, dermatitis, eczema, diarrhea, boils and sore throat. Senecio is distributed in 22 provinces and autonomous regions across the country. In Guangdong Province, Senecio is distributed in 18 prefecture-level cities, most notably in western Guangdong. [0003] Senecio has a broad-spectrum antibiotic effect, and has a strong inhibitory effect on Staphylococcus a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/28A61K9/08A61P31/04A61P11/00A61P1/00
CPCA61K36/28A61K9/0019A61K9/08A61K31/505A61K47/10A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 陈进军聂芳红陈进东何盛昱林红英
Owner GUANGDONG OCEAN UNIVERSITY
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