Pharmaceutical composition for treating non-infectious inflammatory skin diseases and preparation method thereof

An inflammatory skin disease, non-infectious technology, used in drug combinations, skin diseases, medical preparations with non-active ingredients, etc., can solve problems such as skin telangiectasia, inability to cure skin diseases, steroid acne, etc. The effect of optimization and growth, avoidance of recurrence after recovery, and elimination of inflammation

Active Publication Date: 2017-11-24
SICHUAN DEFENG PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Most of the existing medicines for the treatment of non-infectious inflammatory skin diseases are western medicines, which have the characteristics of quick effect and fast curative effect, such as compound flumetasone ointment (Aushen), etc.; Recurrence, skin disease cannot be cured, it is skin disease patients struggling to deal with recurrence after recovery
At the same time, Western medicine preparations often cause skin telangiectasia, skin purpura, or steroid acne symptoms

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Pharmaceutical composition ointment for the treatment of non-infectious inflammatory skin diseases:

[0023] (1) Mix cnidium, herb and bletilla striata with a mass ratio of 1:1:1, add water and decoct three times, each time for 1.5 hours, add 12 times the amount of water for the first time, add 8 times the amount of water for the second time, and add water for the second time Add 4 times the amount of water three times, combine the decoction, filter, and concentrate the filtrate to a relative density of 1.5 at 60°C to obtain a traditional Chinese medicine extract;

[0024] (2) Preparation of emulsion-type base: by weight ratio: 90 parts of cetearyl alcohol, 15 parts of glyceryl monostearate, 10 parts of beeswax, 70 parts of light liquid paraffin, ethylparaben 1 part is heated and melted into the oil phase, and another 50 parts of propylene glycol and 700 parts of distilled water are heated to 90°C, and then 10 parts of sodium lauryl sulfate is added to dissolve into the...

Embodiment 2

[0027] Pharmaceutical composition gel for the treatment of non-infectious inflammatory skin diseases:

[0028] (1) Mix cnidium, herb and bletilla striata with a mass ratio of 1:1:1, add water and decoct three times, each time for 1.5 hours, add 12 times the amount of water for the first time, add 8 times the amount of water for the second time, and add water for the second time Add 4 times the amount of water three times, combine the decoction, filter, and concentrate the filtrate to a relative density of 1.3 at 60°C to obtain a traditional Chinese medicine extract;

[0029] (2) Dissolve 20g of ethylparaben with 1000g93% ethanol to obtain an ethanol solution of ethylparaben for subsequent use;

[0030] (3) Add 5g of disodium edetate and 1500g of propylene glycol into 6683g of distilled water to dissolve completely, then add 120g of carbomer and stir to dissolve, then add 70g of triethanolamine, stir, then add 2g of flumetasone pitavarate and 300g of water Salicylic acid, 300g...

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PUM

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Abstract

The invention discloses a drug composition for treating non-infectious inflammatory dermatosis, which comprises the following ingredients by mass percentage: 0.02% of flumethasone pivalate, 3% of salicylic acid, 3% of traditional Chinese medicine extract and the balance of pharmaceutically acceptable adjuvant. The composition is compounded by Chinese and western medicines, has a good curative effect, takes effect quickly, can effectively promote optimization and growth of epidermal cells, enhance plastids of the epidermal cells, remove inflammation, rapidly recovers an injured organism, and avoids relapses after curing due to re-infection of bacteria. After the composition is used, no purpura and / or steroid acne exist / exists on the surface of skin.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating non-infectious inflammatory skin diseases and a preparation method thereof. Background technique [0002] Dermatosis is a high incidence of diseases, manifested symptoms mainly on the skin surface, for example, non-infectious inflammatory skin diseases: seborrheic dermatitis, contact dermatitis, atopic dermatitis, localized neurodermatitis, vulgaris Psoriasis, lichen planus, and palmoplantar hyperkeratosis, etc., not only bring inconvenience to patients' daily life and interpersonal communication, but also cause great harm to patients' body and mind. Most of the existing medicines for the treatment of non-infectious inflammatory skin diseases are western medicines, which have the characteristics of quick effect and fast curative effect, such as compound flumetasone ointment (Aushen), etc.; Recurrence, can not cure skin disease, is that skin disease patients are struggling to deal with ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/898A61K9/06A61P17/00A61K31/57A61K31/60
CPCA61K9/0014A61K9/06A61K31/57A61K31/60A61K36/234A61K36/284A61K36/898A61K47/32A61K47/44A61K2236/331A61K2236/39A61K2300/00
Inventor 王俊贤袁端锋
Owner SICHUAN DEFENG PHARMA CO LTD
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