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A health food composition for preventing osteoporosis and its preparation method

A technology for health food and osteoporosis, applied in the field of health food, can solve the problems of increasing the risk of endometrial cancer and breast cancer, uncertain long-term efficacy, and reducing the therapeutic effect, so as to stimulate the proliferation of bone cells and inhibit osteoclasts. Cell differentiation, less toxic and side effects

Active Publication Date: 2017-01-11
贵州省科晖制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Western medicine mostly uses estrogen replacement therapy, but this method will have adverse effects on other target organs such as breast and uterus, increase the risk of endometrial cancer and breast cancer, and cause coronary heart disease, cerebral thrombosis, cholecystitis, etc. Therefore, there are certain restrictions on the use of
However, there are also some problems in other treatment methods, such as uncertain long-term curative effect, high price, poor calcium absorption, etc., and clinical application in stages, patients often cannot grasp and persist, and the compliance is poor, which makes the treatment effect great. to reduce

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 2

[0027] Carry out anti-osteoporosis pharmacodynamics experiment with the capsule obtained in Example 2 of the present invention

[0028] 1. Experimental animals: SD female rats, SPF grade, body weight 200-250g, animal certificate number: SCXK (Chongqing) 2012-0005.

[0029] 2. Feeding conditions: Animals are reared and managed by special personnel, fed in separate cages, and single caged. Common rat chow. The laboratory is well-lit and well-ventilated, with a room temperature of 18-26°C and a humidity of 40-70%.

[0030] 3. Establishment of osteoporosis rat model: after 2 weeks of adaptation to feeding, anesthetize with pentobarbital sodium solution and intraperitoneal injection of 0.3ml / 100g body weight, take prone position, cut off long hair, routine disinfection, incision on the back, and ovariectomy , sprinkled with penicillin powder, sutured, put them back into the cage in a side-lying position, and drank water normally. The sham operation group performed the same steps,...

Embodiment 1

[0052] A health food composition for preventing osteoporosis, comprising the following steps:

[0053] (1) Weigh 9g of kudzu root, 9g of poria cocos, 3g of turmeric, 9g of Chinese yam, and 9g of coix seed, freeze-dry and dehydrate at low temperature, and grind them into raw powder for later use;

[0054] (2) Weigh drynaria rhizome 3g, astragalus 9g, decoct three times with 7 times the total amount of medicinal materials, the first 2h, the second 1.5h, the third 1h, combine the decoction, filter, and concentrate the filtrate to Extraction with a temperature of 60°C and a relative density of 1.23, dried and pulverized;

[0055] (3) Mix the raw powder obtained in step (1) with the dry extract powder in step (2), add dextrin, magnesium stearate, cross-linked polyvinylpyrrolidone, steviol glycoside, uniformly granulate, press piece.

[0056] Example 2

[0057] A health food composition for preventing osteoporosis, comprising the following steps:

[0058] (1) Weigh 15g of kudzu ...

Embodiment 3

[0062] A health food composition for preventing osteoporosis, comprising the following steps:

[0063] (1) Weigh 12g of kudzu root, 12g of poria cocos, 7g of turmeric, 23g of yam, 20g of coix seed, freeze-dry and dehydrate at low temperature, and then ultrafinely pulverize it into a raw powder for later use;

[0064] (2) Weigh drynaria rhizome 9g and astragalus root 20g, decoct in water 6 times the total weight of the medicinal materials for three times, the first time for 2 hours, the second time for 1.5 hours, and the third time for 1 hour, combine the decoction, filter, and concentrate the filtrate to Extraction with a temperature of 60°C and a relative density of 1.30, dried and pulverized;

[0065] (3) Mix the raw powder obtained in step (1) with the dry extract powder in step (2), add dextrin, magnesium stearate, steviol glycoside or sucrose, mix evenly, and make granules according to the conventional process.

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PUM

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Abstract

The invention discloses a health food composition for preventing osteoporosis. The health food composition is prepared from the following raw materials in parts by weight: 3-15 parts of drynaria rhizome, 9-30 parts of astragalus membranaceus, 9-15 parts of roots of kudzu vine, 9-15 parts of poria cocos, 3-10 parts of rhizoma curcumae longae, 9-30 parts of Chinese yam and 9-30 parts of coix seeds. A preparation method for the health food composition comprises the following steps: weighing the roots of kudzu vine, the poria cocos, the rhizoma curcumae longae, the Chinese yam and the coix seeds in parts by weight, and crushing into raw powder after drying and dehydrating; weighing the drynaria rhizome and the astragalus in parts by weight, decocting with water, concentrating into paste, drying and crushing; uniformly mixing the raw powder and dry extract powder, and adding auxiliary materials to prepare the health food preparation. The health food composition for preventing osteoporosis provided by the invention has the characteristics of being reasonable in price, remarkable in effect and free of toxic or side effect.

Description

technical field [0001] The invention belongs to the field of health food, and in particular relates to a health food composition for preventing osteoporosis and a preparation method of the health food composition. Background technique [0002] Osteoporosis is a clinical syndrome characterized by decreased bone mass and decreased bone strength, resulting in localized bone pain, deformity and fractures. The onset is related to endocrine disorders and calcium malabsorption, and can be divided into primary and secondary. The onset of osteoporosis is insidious. Once discovered, most of them have developed to a certain extent. The incidence of bone loss and fractures increases significantly with age. Osteoporotic fractures can occur anywhere, but are more common in the vertebrae, wrists, and hips. Hip fractures are the most serious and often require surgical treatment, and patients often have chronic diseases, such as hypertension, cardiovascular disease, chronic obstructive re...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A23L33/00A61K36/9066A61P19/10
CPCA23V2002/00A61K36/00A23V2200/30A23V2250/5114A23V2250/628A23V2250/51084A23V2250/5118A23V2250/032A23V2250/6422
Inventor 陆宽刘建华张杰高玉琼霍昕杨迺嘉
Owner 贵州省科晖制药有限公司