Beam Shapers for Neutron Capture Therapy

Abstract

In order to improve the flux and the quality of a neutron source, the invention provides a beam shaping body for neutron capture therapy. The beam shaping body comprises a beam inlet, a target, a retarding body adjacent to the target, a reflecting body surrounding the external of the retarding body, a thermal neutron absorber adjacent to the retarding body, and a radiation shield and a beam outlet formed in the beam shaping body, wherein the target has nuclear reaction with proton beam entering from the beam inlet, so as to produce a neutron; the neutron forms a neutron beam; the neutron beam defines a main axis; the retarding body slows down the neutron produced by the target to an epithermal neutron energy region; the retarding body is designed to a shape containing at least one cone; the reflecting body guides the neutron deviated from the main axis back to the main axis, so as to improve the strength of an epithermal neutron beam; the thermal neutron absorber is used for absorbing a thermal neutron, so as to prevent the thermal neutron from causing excessive dosage with a superficial normal tissue during therapy; the radiation shield is used for shielding leaked neutron and photon, so as to reduce the normal tissue dosage of a non-irradiated region.

Description

technical field [0001] The invention relates to a beam shaping body, in particular to a beam shaping body for neutron capture therapy. Background technique [0002] With the development of atomic science, radiation therapy such as cobalt 60, linear accelerator, and electron beam has become one of the main means of cancer treatment. However, traditional photon or electron therapy is limited by the physical conditions of the radiation itself. While killing tumor cells, it will also cause damage to a large number of normal tissues along the beam path; in addition, due to the different sensitivity of tumor cells to radiation, traditional radiation therapy Treatment outcomes for more radiation-resistant malignancies (eg, glioblastoma multiforme, melanoma) are often poor. [0003] In order to reduce the radiation damage to normal tissues around the tumor, the concept of targeted therapy in chemotherapy (chemotherapy) has been applied to radiation therapy; and for tumor cells with...

AI Technical Summary

Problems solved by technology

However, traditional photon or electron therapy is limited by the physical conditions of the radiation itself. While killing tumor cells, it will also cause damage to a large number of normal tissues along the beam path; in addition, due to the different sensitivity of tumor cells to radiation, traditional radiation therapy Treatment of more radiation-resistant malignancies (eg, glioblastoma multiforme, melanoma) is often less effective

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