Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Thermal massage ointment for promoting blood circulation, removing blood stasis, harmonizing collaterals and relieving pain and preparation method thereof

A technology of promoting blood circulation, removing blood stasis, and harmonizing network, which is applied in the field of medicine, can solve problems such as poor particle size distribution uniformity, large particle size of cream, cold resistance and heat resistance oil-water separation, etc., and achieves strong process operability and heavy product Good performance and uniform particle size distribution

Active Publication Date: 2018-05-01
SHINEWAY PHARMA GRP SHANDONG
View PDF2 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the massage ointment recorded in the Pharmacopoeia has a good clinical effect, there is still room for further improvement in the treatment of chronic soft tissue injuries.
[0005] In addition, the preparation method given by Pharmacopoeia Massage Ointment also has certain defects.
The characteristic of this pharmacopoeia method is that after mixing the raw and auxiliary materials, add the traditional Chinese medicine extract, add water, heat, stir, and emulsify. Sexual oil-water separation phenomenon, and centrifugal test layering phenomenon, the yield of the product needs to be improved
In addition, the particle size of the cream prepared by this method is relatively large, and the uniformity of the particle size distribution is poor, which affects the transdermal absorption of the drug, and the massage ointment cannot fully exert the drug effect.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Thermal massage ointment for promoting blood circulation, removing blood stasis, harmonizing collaterals and relieving pain and preparation method thereof
  • Thermal massage ointment for promoting blood circulation, removing blood stasis, harmonizing collaterals and relieving pain and preparation method thereof
  • Thermal massage ointment for promoting blood circulation, removing blood stasis, harmonizing collaterals and relieving pain and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031]

[0032] The preparation method of massage ointment comprises: (1) preparation of traditional Chinese medicine extract: get frankincense, myrrh, black medicine, chuanxiong, turmeric decoction pieces, add 50% ethanol of 7 times the amount of decoction pieces medicine, soak and extract 3 times, each time After 8 days, combine the extracts, add rue extract and belladonna liquid extract, stir well, filter, and adjust the relative density of the filtrate to 20°C to be 0.88 for later use; (2) prepare the oil phase: stearic acid, mono Glyceryl stearate, stearyl alcohol, methyl salicylate, menthol, azone, camphor, clove oil, cinnamon oil, vanillyl butyl ether, simethicone, polyoxyethylene fatty alcohol ether, heating and mixing, Keep it at 70°C for later use; (3) Prepare the water phase: heat and mix water, glycerin, sodium lauryl sulfate, and triethanolamine, and keep it at 70°C for later use; (4) Combine phases: under stirring (speed 100-140r / min) add the water phase to t...

Embodiment 2

[0043]

[0044] The preparation method of massage ointment comprises: (1) preparation of traditional Chinese medicine extract: get frankincense, myrrh, black medicine, chuanxiong, turmeric decoction pieces, add 4 times the amount of 70% ethanol of the decoction pieces, soak and extract 3 times, each 5 day, combine the extracts, add rue extract, belladonna liquid extract, stir evenly, filter, and when the filtrate is adjusted to 20 ℃, the relative density is 0.81 for later use; (2) prepare the oil phase: stearic acid, monohard Fatty acid glycerides, stearyl alcohol, methyl salicylate, menthol, azone, camphor, clove oil, cinnamon oil, vanillyl butyl ether, simethicone, polyoxyethylene fatty alcohol ether heating and mixing, keeping 85°C for standby; (3) Preparation of water phase: heat and mix water, glycerin, sodium lauryl sulfate, and triethanolamine, and keep at 80°C for standby; (4) Composite phase: under stirring conditions (speed 100-140r / min) Add the water phase to th...

Embodiment 3

[0055]

[0056]

[0057] The preparation method of massage ointment comprises: (1) preparation of traditional Chinese medicine extract: take frankincense, myrrh, black medicine, chuanxiong, turmeric decoction pieces, add 2 times the amount of 85% ethanol of the decoction pieces, soak and extract 5 times, each 6 day, combine the extracts, add rue extract, belladonna liquid extract, stir well, filter, and adjust the relative density of the filtrate to 20 ℃ to be 0.80 for later use; (2) prepare the oil phase: stearic acid, monohard Fatty acid glycerides, stearyl alcohol, methyl salicylate, menthol, azone, camphor, clove oil, cinnamon oil, vanillyl butyl ether, simethicone, polyoxyethylene fatty alcohol ether heating and mixing, keeping Standby at 90°C; (3) Preparation of water phase: heat and mix water, glycerin, sodium lauryl sulfate, and triethanolamine, and keep at 90°C for standby; (4) Composite phase: under stirring conditions (speed 100-140r / min) Add the water phase ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a thermal massage ointment for promoting blood circulation, removing blood stasis, harmonizing collaterals and relieving pain. , menthol, cinnamon oil, clove oil, and camphor are prepared from twelve traditional Chinese medicines. In addition, the present invention also relates to a preparation method of the thermal massage ointment, which mainly includes the following steps: (1) preparation of traditional Chinese medicine extract, (2) preparation of oil phase, (3) preparation of water phase and (4) combination. The massage ointment of the invention is more suitable for treating chronic soft tissue injuries. The massage ointment preparation method of the present invention has the characteristics of strong process operability, good product reproducibility, and high yield, and the massage ointment prepared by it has the characteristics of small emulsion particle size, uniform particle size distribution, and high transdermal absorption rate. The fuller characteristics of the medicinal effect.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a massage ointment for promoting blood circulation, removing blood stasis, harmonizing collaterals and relieving pain and a preparation method thereof. Background technique [0002] Soft tissue injuries can be divided into acute injuries, new injuries and chronic injuries according to time. Acute injury refers to within 24 hours after the injury. At this time, the main local pathological changes are tissue tearing or rupture, and small blood vessels rupture and bleeding. The symptoms are swelling, pain, heat, dysfunction, etc. At this time, it should be avoided and treated as much as possible. To reduce bleeding, exudation, and edema in damaged soft tissues, braking, cold compresses, and pressure bandages should be taken immediately. More than 24 to 48 hours after the injury of the newly injured finger, the local bleeding stops at this time, and the decomposition products of necrotic tis...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/06A61K36/9066A61P29/00A61K31/618
Inventor 杨宝翠刘铁军倪永良屈云萍姜国志刘艳丽孙胜斌陈翔宇李英丽李菲李龙龙关秀伟
Owner SHINEWAY PHARMA GRP SHANDONG
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com