Probe used for TORCH detection, gene chip and kit thereof

A gene chip and kit technology, applied in the field of TORCH detection probes, gene chips and kits, can solve the problems of increasing application cost, restricting market application and promotion, weak signal, etc., achieving good results, improving detection efficiency and improving detection efficiency. The effect of high accuracy and signal resolution
CN104846074AActive Publication Date: 2015-08-19ZHUHAI SINOCHIPS BIOSCIENCE CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
ZHUHAI SINOCHIPS BIOSCIENCE CO LTD
Publication Date
2015-08-19

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Abstract

The invention discloses a set of probes used for TORCH detection, and comprises a toxoplasma TOX probe which is shown in a SEQ ID NO. 1; a rubella virus RV probe which is shown in a SEQ ID NO.2; a cytomegalovirus CMV probe which is shown in a SEQ ID NO.3; a herpes simplex virus HSV I type probe which is shown in a SEQ ID NO.4; and a herpes simplex virus HSV II type probe which is shown in a SEQ ID NO.5. The invention also comprises a gene chip containing the probe and a kit thereof, visible light passing through a biochip can be amplified, signal resolution is high, and a signal can be shoot by a common digital camera or directly read by naked eyes. Compared with a traditional fluorescent label, the gene chip has good effect. Through specific primer and probe selection, by combining a gene chip technology, detection efficiency and accuracy degree are increased, and requirement of on-site detection for hospital and antenatal testing.
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Description

technical field

[0001] The invention relates to the field of biotechnology, in particular to a group of probes, gene chips and kits for TORCH detection Background technique

[0002] TORCH refers to the pathogen that can cause congenital intrauterine infection and perinatal infection and cause perinatal malformation. It is the abbreviation of the English name of a group of pathogenic microorganisms. T (Toxopasma) is Toxoplasma gondii, R (Rubella.Virus) is rubella Virus, C (Cytomegalo.Virus) is a giant cell, H (Herpes.Virus) is herpes simplex type I / II.

[0003] This group of microbial infections has a common feature, which can cause mother-to-child infection. Pregnant women are prone to primary infection due to endocrine changes and decreased immunity, and the latent virus in pregnant women who have been infected before is also prone to reactivation and recurrent infection. When viremia occurs in pregnant women, the virus can be transmitted through the placenta or birth can...

Claims

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