Double-layer intestinal tract suppository with two protruding parts

Abstract

The invention discloses a double-layer intestinal tract suppository with two protruding parts. The double-layer intestinal tract suppository is columnar; the total length of the double-layer intestinal tract suppository ranges from 2 to 4cm; the double-layer intestinal tract suppository comprises a coaxial head part (1), a coaxial suppository body (2), and a coaxial tail part (3) from the top part to the bottom part; the suppository body (2) is shaped like a cylinder; the head part (1) is shaped like a spherical cap; the tail part (3) is shaped like a spherical segment; the diameter of the suppository body cylinder ranges from 3 to 10mm; the diameter of the sphere to which the head part spherical cap belongs is 1.1 to 1.2 times of the diameter of the suppository body cylinder; the ratio of the diameter of the sphere to which the tail part spherical segment belongs to the diameter of the sphere to which the head part spherical cap belongs is 1.2-1.4:1; cambered surfaces are adopted for transition of the head part (1), the tail part (3), and the suppository body (3); a suppository core (4) is arranged in the double-layer intestinal tract suppository; the suppository core (4) is a cylinder with a diameter of 1 to 1.5cm and a height of 1 to 1.5cm; the suppository core (4) and the double-layer intestinal tract suppository are coaxial, and are separated via a microporous membrane (6); and trepanning ratio of the microporous membrane (6) ranges from 20 to 40%.

Description

field of invention [0001] The invention relates to a suppository. Background technique [0002] Suppository (Suppository) refers to a solid preparation made of a drug and a suitable matrix with a certain shape for administration in the human cavity. Suppositories are solid at room temperature. After being inserted into the cavity, they can quickly soften and melt or dissolve in secretions at body temperature, and gradually release drugs to produce local or systemic effects, and effectively avoid the first-pass effect of the liver. More and more people are using it, but because the suppository for treating the intestinal tract has insufficient contact with the intestinal wall, the release and absorption speed of the suppository are slow. Contents of the invention [0003] The invention provides an intestinal suppository, the plug body is a columnar body, the total length of the plug body is 2-4cm, and the head crown 1, the plug body 2, and the tail crown 3 are sequentially...

AI Technical Summary

Problems solved by technology

Suppositories are solid at room temperature. After being inserted into the cavity, they can quickly soften and melt or dissolve in secretions at body temperature, and gradually release drugs to produce local or systemic effects, and effectively avoid the first-pass effect of the liver. More and more people use it, but due to the insufficient contact between the existing suppositories for treating the intestinal tract and the intestinal wall, the release and absorption of the suppositories are slow

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