Composite underleaf pearl preparation and application in dietary for dog

A compound and preparation technology, applied in the field of compound Phyllostachys phylloxera preparations, achieves the effects of high development value, simple extraction and separation process, and convenient production

Inactive Publication Date: 2015-12-23
FUJIAN AGRI & FORESTRY UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The method of perfusion can effectively reduce the load on exogenous organs, reduce the inflammatory reaction at the injection site, and reduce the mortality of experimental animals during the preparation of animal models, but the dosage of perfusion still needs further research

Method used

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  • Composite underleaf pearl preparation and application in dietary for dog
  • Composite underleaf pearl preparation and application in dietary for dog
  • Composite underleaf pearl preparation and application in dietary for dog

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] The preparation of embodiment 1 compound phylloxera preparation

[0018] Every 5g of the whole plant under the leaf is crushed, add 150mL of distilled water and stir evenly, soak for 16h, decoct for 45min in a slightly boiling state, and filter off the supernatant. Add 150 mL of distilled water to the filter residue, soak for 8 hours, decoct in a slight boiling state for 35 minutes, and filter off the supernatant. Add 150 mL of distilled water to the filter residue, soak for 8 hours, decoct in a slight boiling state for 35 minutes, and filter off the supernatant. The combined three filtrates were concentrated under reduced pressure to 40 mL. The same method is used to decoct the roots of Sansevieria verticillium, combine the extracts of Phyllanthus phylloxera and Rhizoma Sansevieriae, further concentrate to 40mL, and store at 4°C for later use.

Embodiment 2

[0019] Example 2 Effect of compound phylloxera preparation on liver function index of carbon tetrachloride liver injury in dogs

[0020] 1 Materials and methods

[0021] 1.1 Test materials and instruments

[0022] Carbon tetrachloride: batch number 20140218, manufacturer Sinopharm Chemical Reagent Co., Ltd.

[0023] Rapeseed oil: Arowana rapeseed oil was purchased from Yonghui Supermarket in Fuzhou City.

[0024] Bifendate dripping pills: Approval number Guoyao Zhunzi H11020980, manufacturer Beijing Concord Pharmaceutical Factory.

[0025] The dried whole plant of Phyllostachys phylloxera and Rhizoma chinensis root were purchased in Zhangzhou, Fujian, and were identified as Phyllostachys phylloxera and Rhizoma chinensis.

[0026] Alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALKP) kits were provided by Nanjing Jiancheng Bioengineering Institute.

[0027] 800D desktop vulgar centrifuge (Shanghai Medical Instrument Co., Ltd. Surg...

Embodiment 3

[0060] Example 3 Effect of Compound Phyllostachys phylloxera preparation on the antioxidant index of carbon tetrachloride liver injury in dogs

[0061] 1 Materials and methods

[0062] 1.1 Test materials and instruments

[0063] Carbon tetrachloride: batch number 20140218, manufacturer Sinopharm Chemical Reagent Co., Ltd.

[0064] Rapeseed oil: Arowana rapeseed oil was purchased from Yonghui Supermarket in Fuzhou City.

[0065] Bifendate dripping pills: Approval number Guoyao Zhunzi H11020980, manufacturer Beijing Concord Pharmaceutical Factory.

[0066] The dried whole plant of Phyllostachys phylloxera and Rhizoma chinensis root were purchased in Zhangzhou, Fujian, and were identified as Phyllostachys phylloxera and Rhizoma chinensis.

[0067] Glutathione (GSH), malondialdehyde (MDA), and total superoxide dismutase (T-SOD) kits were all provided by Nanjing Jiancheng Bioengineering Institute.

[0068] 800D desktop vulgar centrifuge (Shanghai Medical Instrument Co., Ltd...

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Abstract

The invention provides a composite underleaf pearl preparation and an application thereof. The composite underleaf pearl preparation is formed by merging and concentrating underleaf pearl full-grass filter solution and uraria crinite filter liquid. The application in the dietary for the dog shows that the composite underleaf pearl preparation has an obvious enzyme reduction effect and an obvious antioxidation effect, can effectively repair the cellular degeneration after liver is damaged, can reduce the liver connective tissue proliferation and fibrosis and can be used for researching an animal healthcare product for the dog. The composite underleaf pearl preparation is not reported at present to have the effect for protecting the liver. Compared with other existing healthcare products of the dog, the toxicity and side effect are small, no adverse reaction is produced, the antioxidation effect is realized, and the composite underleaf pearl preparation can be used for a long time; the composite underleaf pearl preparation is easy for obtaining raw materials, low in price, simple in extraction and separation process, convenient to produce and high in development value.

Description

technical field [0001] The invention belongs to the field of veterinary medicine, and in particular relates to a compound phylloxera preparation and application thereof. Background technique [0002] Plants of the genus Phyllophyllum under the Euphorbiaceae family ( Phyllanthusurinaria L. ), also known as pearl grass, yin and yang grass, etc., is a commonly used Chinese herbal medicine in Fujian Province and is widely popular among the people. Phyllostachys phylloxera is cool in nature, sweet and bitter in taste, enters the liver and spleen meridian, has the effects of calming the liver and clearing away heat, clearing the liver and improving eyesight, eliminating malnutrition, stopping dysentery, diuresis, etc., and external application has the effect of reducing swelling and detoxification. [0003] Zhou Baohua and Li Ling supplemented phylloxera in the treatment of 62 clinical cases of chronic hepatitis B, and the results were significant, indicating that phylloxera can ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/48A23K1/18A23K1/16A61P1/16
Inventor 黄志坚殷光文江和基熊澎奎
Owner FUJIAN AGRI & FORESTRY UNIV
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