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Cell collecting device

A cell and sample collection technology, applied in the field of devices for collecting cells from biological samples, can solve problems such as increasing the risk of cell deterioration, damage to analysis materials, and difficulty in making a diagnosis, so as to reduce the risk of damage, reduce the need, The effect of reducing the chance

Inactive Publication Date: 2016-02-24
TSI科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The cellular material contained within a biological sample degrades over time, and any delay between obtaining a sample and analyzing it can therefore cause the analyzed material to become damaged
This can affect the results obtained, and / or make the diagnosis difficult
Therefore, the necessity to use specialized equipment that requires sending samples to distant laboratories for isolation and analysis is undesirable as it would delay introduction into the process, thus increasing the risk of spoilage of the extracted cells

Method used

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Examples

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Embodiment Construction

[0052] first reference figure 1 , shows the components of the first embodiment of the cell collection device 10 . The device 10 comprises four main parts / assemblies, namely an inlet funnel 11 , a bottom container 13 , a cell collection membrane 14 (with support ring 15 ) and a fluid absorption assembly 19 . In the assembled device 10, the cell collection membrane 14 and fluid absorbent assembly 19 are adsorbed between the inlet funnel 11 and the bottom container 13, as described below. The device has an overall height of approximately 10 cm.

[0053] The bottom container 13 is a cylindrical container with an open top. The inlet funnel 11 has the form of a hollow, conical cylinder, open at both ends. A ring 111 is integrally formed with the lower (as seen in the figures) end of the inlet funnel 11 and forms a channel 112 between the wall of the inlet funnel 11 and the ring 111 . The outer surface of the rim of the bottom receptacle 13 and the inner surface of the ring 111 a...

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Abstract

A device for collecting cells from a sample of biological fluid comprises first and second chambers (11, 3) that are releasably connected and which define a fluid flow path from the first chamber (11) to the second chamber (13). A porous membrane (14) is captivated between the first and second chambers (11, 13) when the first and second chambers (11, 13) are connected to each other, in the fluid flow path. An absorbent body (17) is positioned in close proximity to the downstream surface of the porous membrane (14), and a resilient member (18) is arranged to urge the absorbent body (17) towards the porous membrane (14). In use, a sample introduced into the first chamber (11) contacts the upstream surface of the porous membrane (14) and fluid is drawn through the porous membrane (14) and is absorbed by the absorbent body (17). Cells present in the sample are retained upon the upstream surface of the porous membrane (14). After separation of the first and second chambers (11, 13), the porous membrane (14) can be removed from the device for analysis of the deposited cells.

Description

technical field [0001] The present invention relates to a device for collecting cells from a biological sample. Background technique [0002] To enable analysis of cells, it is often necessary to separate and collect cells from biological samples. For example, it may be necessary to diagnose and / or treat some diseases. For example, analysis of cells extracted from a urine sample can be used to diagnose bladder cancer, or isolation of cells from stool can be used to diagnose cancers of the gastrointestinal tract. [0003] It is routine to collect cells from fluid samples using centrifugal force, where the force exerted by high speed centrifugal force causes larger, denser particles in the sample to settle out. Typically, larger particles include cellular material contained within the sample that has been separated from the fluid components of the sample. Once the cellular material has been obtained, it can be analyzed using microscopy or other analytical methods. [0004]...

Claims

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Application Information

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IPC IPC(8): G01N1/40B01L3/00B01D29/05
CPCB01L3/502B01L2200/025B01L2200/026B01L2200/028B01L2200/0647B01L2300/0681B01L2300/069B01L2300/087B01L2300/12B01L2300/123B01L2400/0406G01N2001/4088
Inventor S·科顿
Owner TSI科技有限公司
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