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An interactive dose-gradient-based optimization technique for controlling the complexity of imrt delivery

A dose gradient, optimizer technology, applied in the medical field, can solve problems such as difficult to solve, and achieve the effect of reducing calibration time and cost, easy identification, and increasing predictability

Active Publication Date: 2019-05-14
KONINKLJIJKE PHILIPS NV
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, the direct aperture-based optimization problem is much more difficult to solve than the fluence-based optimization

Method used

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  • An interactive dose-gradient-based optimization technique for controlling the complexity of imrt delivery
  • An interactive dose-gradient-based optimization technique for controlling the complexity of imrt delivery
  • An interactive dose-gradient-based optimization technique for controlling the complexity of imrt delivery

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Experimental program
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Embodiment Construction

[0028] This application provides functionality to optimize IMRT planning using dose gradient based optimization. The present application provides functionality for storing and accessing patient-specific treatment planning data, wherein the data includes multiple distributed sources. This application provides functionality to perform an initial optimization of the treatment plan. The present application provides functionality to generate dose gradient maps based on treatment planning data. The application provides functionality to specify dose gradients for specific regions in the beam direction view and for a single beam from the multiple beams used in planning. The application also provides functionality to perform a final optimization of the plan. This application provides functionality to accept user input and display the results to the user in real time for planning maneuvers.

[0029] The dose gradient is directly proportional to the intensity modulation such that modi...

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Abstract

A method for dose gradient-based optimization of intensity-modulated radiation therapy planning. First, an optimizer (6) performs a first optimization (40) of the plan to generate a dose distribution corresponding to the plan. Next, the optimizer (6) generates a beam-specific dose gradient map (42) for each beam of the plan. A new dose gradient is then specified (44) for the plan. Finally, the optimizer (6) performs a final optimization (46) using the new dose gradient. The new dose gradient is brought into the objective function as a soft constraint to give the final optimization. The optimizer (3) applies a limiting factor to the objective function such that the first dose gradient is limited by the optimizer only when the first dose gradient exceeds the new dose gradient for a particular beamlet.

Description

technical field [0001] The present application relates to the field of medicine and is particularly applicable to radiation treatment planning and will be described with particular reference to radiation treatment planning. However, it should be appreciated that the present application is applicable to other medical interventions and procedures as well. When a patient is diagnosed with cancer, several treatment options can be pursued. One treatment option is radiation therapy. When radiation therapy is selected, a detailed plan is constructed based on extensive data about the patient. Background technique [0002] Over the past decade, technological advances have provided large leaps in the fields of intensity modulated radiation therapy (IMRT), intensity modulated photon therapy (IMPT), etc., to improve dose delivery. Recently, research interest has turned towards methods to automate the various tasks involved in plan generation, starting from beam placement to dose opti...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61B6/00
CPCA61N5/1045A61N5/1031A61N5/1036A61N5/1077A61N2005/1074
Inventor V·兰加纳坦G·乔安托P·库马尔S·克里希奈耶拉曼D·U·马哈詹
Owner KONINKLJIJKE PHILIPS NV
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