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A kind of traditional Chinese medicine composition for treating psoriasis and preparation method thereof

A composition and technology for psoriasis, applied in the field of medicine and health, can solve problems such as unfavorable long-term use, toxic and side effects, and achieve the effects of reducing toxic and side effects, promoting tissue repair, and promoting the formation of a tail scale particle layer

Active Publication Date: 2019-12-13
GUANGXI WUZHOU PHARMA GRP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Among them, Tripterygium wilfordii is a common drug that can effectively treat psoriasis, but the active ingredient of Tripterygium wilfordii is also a toxic ingredient, which has serious toxic and side effects on the human body and is not conducive to long-term use.

Method used

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  • A kind of traditional Chinese medicine composition for treating psoriasis and preparation method thereof
  • A kind of traditional Chinese medicine composition for treating psoriasis and preparation method thereof
  • A kind of traditional Chinese medicine composition for treating psoriasis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0058] Fresh dendrobium candidum 6kg is net-selected, cut into sections, sprayed with 75% ethanol for disinfection, and placed in a vacuum freeze dryer together with propolis 0.2kg for freeze-drying;

[0059] Take 15kg of Desmodium spp., 25kg of Chrysanthemum japonica, and 10kg of yellow yam, add 10 times of purified water to reflux and extract 3 times, each extraction time is 3 hours, 2 hours, 1 hour respectively, combine the extracts, filter, and concentrate the filtrate to 60 The liquid extract with a relative density of 1.05-1.20 at ‐80°C is dried at a low temperature in a vacuum dryer to obtain a dry extract of water extract;

[0060] Take 15kg of Tripterygium wilfordii and pulverize it into coarse powder, reflux extraction with 95% ethanol, extract twice, each time for 5 hours and 2 hours respectively, filter, combine the extracts, recover ethanol to obtain Tripterygium wilfordii extract, extract the extract with chloroform 3 times, after concentration, pass through a si...

Embodiment 2

[0063] Fresh dendrobium candidum 12kg is cleaned, cut into sections, sprayed with 70% ethanol for disinfection, and placed in a freeze dryer together with propolis 0.6kg for freeze drying;

[0064] Take 30kg of Desmodium syringae, 40kg of P. japonica, and 32kg of Chinese yam, add 10 times of purified water and hot-dip to extract 4 times, each time for 3 hours, combine the extracts, filter, and when the filtrate is concentrated to 60-80°C, the relative density is 1.05-1.20 liquid extract, vacuum-dried to obtain the water extract dry paste;

[0065] Get 25kg of Tripterygium wilfordii and grind it into coarse powder, reflux extraction with 50% ethanol, extract 4 times, each time for 4 hours, filter, combine the extracts, reclaim ethanol to obtain Tripterygium wilfordii extract, extract the extract 5 times with ethyl acetate, The ethyl acetate layer was taken, the solvent was recovered, and dried in vacuum to obtain a dry paste.

[0066] Grind the dried dendrobium officinale, pro...

Embodiment 3

[0068] Fresh dendrobium candidum 10kg is cleaned, cut into sections, sprayed with 80% ethanol for disinfection, and placed in a freeze dryer together with propolis 0.4kg to freeze-dry;

[0069] Take 21kg of Desmodium syringae, 32kg of Chrysanthemum japonica, and 25kg of Huangyam yam, add 10 times of purified water and hot-dip to extract 4 times, each time for 3 hours, combine the extracts, filter, and when the filtrate is concentrated to 60-80°C, the relative density is 1.05-1.20 liquid extract, vacuum-dried to obtain the water extract dry paste;

[0070] Get 20 kg of Tripterygium wilfordii and grind it into coarse powder, reflux extraction with 50% ethanol, extract 4 times, each time for 4 hours, filter, combine the extracts, reclaim ethanol to obtain Tripterygium wilfordii extract, extract the extract 3 times with ethyl acetate, The ethyl acetate layer was taken, the solvent was recovered, and dried in vacuum to obtain a dry paste.

[0071] Grind the dried dendrobium offici...

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Abstract

The invention discloses a traditional Chinese medicine composition for treating psoriasis and a preparation method thereof. The composition is prepared from snowbell-leaf tickclover herb, common threewingnut roots, propolis, dendrobium officinale, bigbract bulbophyllum and rhizomes of dioscorea panthaica Prain et Burk.. The traditional Chinese medicine composition has a significant inhibiting effect on mitosis of the vaginal epitheliums of Kunming mice and a significant promoting effect on formation of tail flaky granular layers of C57 mice and causes smaller damage to the liver under positive control.

Description

technical field [0001] The invention relates to the field of medicine and hygiene, in particular to a traditional Chinese medicine composition for treating psoriasis and a preparation method thereof. Background technique [0002] Psoriasis is a common chronic relapsing inflammatory skin disease. Typical skin lesions are erythema and scales. Therefore, traditional Chinese medicine also calls it "white rash" and "pine skin tinea". The incidence of psoriasis is high in our country. Studies have shown that psoriasis patients in our country account for about 3% of the world's population, and there is an increasing trend year by year. Psoriasis has obvious skin damage, conscious itching, often repeated attacks, protracted and difficult to heal, so it can only be controlled by drugs, using drugs to prevent each attack, and prolong the relief time as much as possible. [0003] On the other hand, dermatologists generally agree that the combination of Chinese and Western medicine is ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8984A61P17/06A61K35/644
CPCA61K9/2059A61K35/644A61K36/37A61K36/48A61K36/8945A61K36/898A61K36/8984A61K2236/331A61K2236/333A61K2236/35A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 杨北妮蒋腾川郑志远林艳英邓裕彦黄源春谭喜梅
Owner GUANGXI WUZHOU PHARMA GRP
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