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Compound blood glucose reducing medicine composition and preparing method thereof

A composition and hypoglycemic technology, applied in the directions of drug combinations, active ingredients of hydroxyl compounds, medical raw materials derived from ferns/filamentous plants, etc., can solve the problems of insignificant hypoglycemic effect, liver and kidney toxicity, adverse reactions, etc. , to achieve the effect of enhancing human vitality, reducing side effects and relieving blood sugar rise

Inactive Publication Date: 2016-06-08
李华红
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These drugs have a certain therapeutic effect on diabetes, but they are also accompanied by many side effects, such as adverse reactions in the digestive tract and certain liver and kidney toxicity, etc., and long-term use of western medicine will produce certain drug resistance and dependence.
However, there are generally cases in which the effect of lowering blood sugar is not obvious in the pure Chinese medicine preparations for the treatment of diabetes.

Method used

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  • Compound blood glucose reducing medicine composition and preparing method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] A compound hypoglycemic pharmaceutical composition, which is composed of the following ingredients in parts by weight: 130 parts of hydrophilic polymer, 56 parts of fermented shallot powder, 35 parts of silk peptide, 30 parts of bracken powder, 30 parts of agar powder, malt 26 parts of trisaccharide alcohol, 23 parts of cyclodextrin, 15 parts of sesamol, 12 parts of mixed enzyme, 10 parts of polypropylene glycol, 8 parts of betahistine, 6 parts of retinoic acid compound, 5 parts of retinoic acid, 3 parts of niacin .

[0018] Wherein, the hydrophilic polymer is hydroxypropyl cellulose. The preparation method of the fermented shallot powder is as follows: fresh shallots are washed, soaked in 0.5% sodium bicarbonate solution for 20 minutes, taken out and chopped, added 5 times the amount of pure water and decocted for extraction for 30 minutes, cooled to 30° C., Obtain the water-extracted mixture of shallots; take the mixture of Aspergillus oryzae, Aspergillus niger and l...

Embodiment 2

[0024] A compound hypoglycemic pharmaceutical composition, which is composed of the following ingredients in parts by weight: 205 parts of hydrophilic polymer, 98 parts of fermented shallot powder, 70 parts of silk peptide, 63 parts of bracken powder, 49 parts of agar powder, malt 40 parts of trisaccharide alcohol, 34 parts of cyclodextrin, 24 parts of sesamol, 20 parts of mixed enzyme, 17.5 parts of polypropylene glycol, 11.5 parts of betahistine, 10.5 parts of retinoic acid compound, 8.5 parts of retinoic acid, 6.5 parts of niacin .

[0025]Wherein, the hydrophilic polymer is carboxymethyl cellulose. The preparation method of the fermented shallot powder is as follows: fresh shallots are washed, soaked in 0.75% sodium bicarbonate solution for 35 minutes, taken out and chopped, added 7.5 times of pure water and decocted for extraction for 35 minutes, cooled to 30° C., Obtain the onion water extraction mixture; take the mixture of Aspergillus oryzae, Aspergillus niger and lac...

Embodiment 3

[0031] A compound hypoglycemic pharmaceutical composition, which is composed of the following ingredients in parts by weight: 280 parts of hydrophilic polymer, 140 parts of fermented shallot powder, 105 parts of silk peptide, 96 parts of bracken powder, 68 parts of agar powder, malt 54 parts of trisaccharide alcohol, 45 parts of cyclodextrin, 33 parts of sesamol, 28 parts of mixed enzyme, 25 parts of polypropylene glycol, 15 parts of betahistine, 15 parts of retinoic acid compound, 12 parts of retinoic acid, 10 parts of niacin .

[0032] Wherein, the hydrophilic polymer is hydroxypropyl cellulose. The preparation method of the fermented shallot powder is as follows: fresh shallots are washed, soaked in 1.0% sodium bicarbonate solution for 50 min, taken out and chopped, added 10 times the amount of pure water and decocted for extraction for 40 min, cooled to 30° C., Obtain the water-extracted mixture of shallot; take the mixture of Aspergillus oryzae, aspergillus niger and lac...

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Abstract

The invention discloses a compound blood glucose reducing medicine composition and a preparing method thereof. The compound blood glucose reducing medicine composition is prepared from, by weight, 130-280 parts of hydrophilic polymer, 56-140 parts of allium victorialis ferment powder, 35-105 parts of silk peptide, 30-96 parts of fiddlehead powder, 30-68 parts of agar powder, 26-54 parts of maltotriose, 23-45 parts of cyclodextrin, 15-33 parts of sesamol, 12-28 parts of mixed enzyme, 10-25 parts of polypropylene glycol, 8-15 parts of betahistine, 6-15 parts of a retinoic acid compound, 5-12 parts of retinoic acid and 3-10 parts of niacin. According to the composition, multiple traditional Chinese medicine effective ingredients and western medicine ingredients are combined and act together to achieve the purpose of controlling increasing of blood glucose; moreover, various indexes of the body of a patient are increased, and cardiovascular health is protected; moreover, the medicine composition is small in side effect, and can not generate an adverse effect on the patient when the patient takes the composition for a long term. In addition, the raw materials of the medicine composition are easy to obtain, the preparation technology is simple, cost is low, economic burdens of the patient are reduced, and the composition is suitable for application and popularization.

Description

technical field [0001] The invention relates to the technical field of diabetes medication, in particular to a compound hypoglycemic pharmaceutical composition and a preparation method thereof. Background technique [0002] Diabetes is caused by genetic factors, immune dysfunction, microbial infection and its toxins, free radical toxins, mental factors and other pathogenic factors acting on the body to cause hypofunction of pancreatic islets and insulin resistance. A series of metabolic disorder syndromes, such as electrolytes and electrolytes, are clinically characterized by elevated plasma glucose levels or hyperglycemia in the fasting state or after administration of glucose in an oral glucose tolerance test. Often abnormal glucose homeostasis is directly and indirectly related to the metabolism of fats, lipoproteins and apolipoproteins as well as other metabolic and hemodynamic diseases. With the improvement of people's living standards, more and more patients suffer fr...

Claims

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Application Information

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IPC IPC(8): A61K38/47A61P3/10A61K36/8962A61K38/01A61K31/203A61K31/455A61K35/64A61K38/45A61K38/43
CPCA61K36/8962A61K31/203A61K31/455A61K35/63A61K36/11A61K38/012A61K38/43A61K38/45A61K38/47A61K2300/00
Inventor 李华红韩晓丽
Owner 李华红
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