Adhesive-dispersion type transdermal patch for cervical spondylosis nursing and preparation method of transdermal patch

Abstract

The invention discloses an adhesive-dispersion type transdermal patch for cervical spondylosis nursing and a preparation method of the transdermal patch. The transdermal patch is prepared from components in parts by weight as follows: 3.6-9 parts of traditional Chinese medicine extract, 0.6-1.2 parts of traditional Chinese medicine nanopowder, 2.3-5 parts of stigmasteryl glucoside, 2.5-4.5 parts of L-selenomethionine, 1.5-3 parts of L-carnitine, 0.2-0.5 parts of meclizine, 1.5-2.3 parts of isopropyl myristate, 1.2-4 parts of stearyl glycyrrhetinate, 2.5-7 parts of stearic acid, 0.2-0.3 parts of a transdermal accelerant, 30-55 parts of adhesive matrixes and 200-280 parts of a dispersing solvent; the traditional Chinese medicine extract is prepared from 0.4-1 part of Chinese starjasmine fruit extract, 0.4-1 part of extract of all-grass of lanceolate blumea, 0.4-1 part of cajuput extract, 0.4-1 part of extract of herba of Allium funckiaefolium Hand.-Mazz., 0.4-1 part of Cissus repens extract, 0.4-1 part of lindley butterflybush root extract, 0.4-1 part of philippine violet herb extract, 0.4-1 part of juniper extract and 0.4-1 part of starntonia chinensis extract; the traditional Chinese medicine nanopowder is prepared from 0.2-0.4 parts of nanopowder of flowers of Chinese redbud, 0.2-0.4 parts of nanopowder of twigs and leaves of creeping psychotria and 0.2-0.4 parts of nanopowder of Bulbophyllum radiatum Lindl.The adhesive-dispersion type transdermal patch has the efficacy of activating the blood, relieving swelling, activating meridians to stop pain and relieving muscle cramp through skin absorption, promotes microcirculation, reduces capillary permeability, eliminates swelling, relieves local stimulation of nerve roots and relives and eliminates pain caused by nerve root type cervical spondylosis.

Description

Technical field [0001] The invention relates to the technical field, in particular to a viscose dispersion type transdermal patch for cervical spondylosis care and a preparation method thereof. Background technique [0002] Cervical spondylosis, also known as cervical syndrome, is the general term for cervical spine osteoarthritis, proliferative cervical spondylitis, cervical nerve root syndrome, and cervical disc herniation. It is a disease based on degenerative pathological changes. Mainly due to long-term cervical spine strain, bone hyperplasia, or intervertebral disc prolapse, ligament thickening, resulting in cervical spinal cord, nerve roots or vertebral artery compression, a series of clinical syndromes of dysfunction. It manifests as cervical disc degeneration itself and its secondary pathological changes, such as instability and loosening of vertebral segments; herniated or prolapsed nucleus pulposus; formation of bone spurs; ligament hypertrophy and secondary spinal ste...

AI Technical Summary

Problems solved by technology

[0003] The current treatment of cervical spondylosis is mainly based on Chinese and Western medicines such as anti-inflammatory, analgesic, and surgery. Oral western medicine can relieve pain symptoms, but the therapeutic effect is not obvious, and these medicines are very harmful to the liver, kidneys, and gastrointestinal tract; Massage, acupuncture and other methods are used for conservative treatment, or physical therapy, but these treatment methods take a long time, the symptoms are not improved obviously, and there are still defects such as easy recurrence after recovery

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