Medicine for preventing and treating qi and blood deficient type piroplasmosis of cattle

A technology for debilitating qi and blood type, bovine coccidiosis, applied in drug combination, drug delivery, pharmaceutical formulation and other directions, can solve problems such as adverse effects on body health, large drug residues, easy to produce drug resistance, etc., and achieve cost price. Inexpensive, no drug residue, no drug resistance effect

Inactive Publication Date: 2016-06-22
李佃场
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] Western medicine generally uses the insecticide triazine or imidazolium, which has a large amount of drug residue, is prone to drug resist

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0063] The toxicity test of the medicine of embodiment 1 present invention

[0064] Take 10g of banyan fig, 7g of milk root, 22g of salsify, 10g of pole, 23g of catechu, 22g of August, 28g of rhizome, 20g of poria cocos, 25g of cassia twig, 7g of saikui, 5g of bletilla, 3g of bitter bark , Jianlan root 13g, seaweed 25g, verbena 17g, wet flat bud 4g, Panax notoginseng 35g, donkey-hide gelatin 28g, Xuemancao 13g, Eupatorium 17g, spoon leaf grass 13g, three stamens 25g, ground astringent 13g, blood Jianchou 19g, lettuce 28g, Gucao 18g, Fengweiqi 10g and mulberry 21g; after mixing evenly, crush, add 1200g of water to the crushed mixture, decoct for 2.5 hours, filter, add to the filter residue 500g of water was decocted again for 1.5 hours, filtered, the two filtrates were mixed, and concentrated under reduced pressure to a decoction whose crude drug concentration was 3g / ml.

[0065] Take ICR mice with a body weight of 25-30 grams, and randomly divide them into groups according to b...

Embodiment 2

[0070] Embodiment 2 Medicine 1 of the present invention and preparation method

[0071] Take 10g of banyan fig, 7g of milk root, 22g of salsify, 10g of pole, 23g of catechu, 22g of August, 28g of rhizome, 20g of poria cocos, 25g of cassia twig, 7g of saikui, 5g of bletilla, 3g of bitter bark , Jianlan root 13g, seaweed 25g, verbena 17g, wet flat bud 4g, Panax notoginseng 35g, donkey-hide gelatin 28g, Xuemancao 13g, Eupatorium 17g, spoon leaf grass 13g, three stamens 25g, ground astringent 13g, blood Jianchou 19g, lettuce 28g, Gucao 18g, Pteris seven 10g and mulberry 21g;

[0072] When the dosage form of described medicine is powder injection, its preparation method comprises the following steps:

[0073] In the first step, the raw medicinal materials are mixed in proportion, put into an ultrafine pulverizer and pulverized into a mixed powder composed of micron-sized particles with a volume average particle size of 1 μm and nano-sized particles with a volume average particle s...

Embodiment 3

[0076] Embodiment 3 Medicine 2 of the present invention and preparation method

[0077] Take 6g of banyan fig, 12g of milk pulp root, 14g of salsify ginseng, 20g of pole, 21g of catechu, 17g of August phlox, 31g of rhizoma rhizome, 30g of poria cocos, 18g of cassia twig, 15g of saikui, 2g of bletilla, 4g of bitter bark , Jianlan root 19g, seaweed 14g, verbena 15g, wet flat bud 11g, panax notoginseng 30g, donkey-hide gelatin 22g, Xuemancao 14g, eupatorium 15g, spoon leaf grass 16g, three stamens 18g, ground astringent 25g, blood Jianchou 16g, lettuce 20g, Gucao 27g, Pteris seven 8g and mulberry 15g;

[0078] When the dosage form of the pharmaceutical composition is powder, its preparation method comprises the following steps:

[0079] The first step is to mix Ficus cuspidatum, milk pulp root, salsify ginseng, stalk and catechu according to the stated ratio, dissolve it in ethanol with an alcohol concentration of 85%% relative to 4 times the mass of the obtained mixture, and he...

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Abstract

The invention discloses a medicine for preventing and treating qi and blood deficient type piroplasmosis of cattle. The medicine comprises ficus esquiroliana, ficus formosana roots, salsifies, grewia biloba, berchemia sinica, akebia trifoliata koidz, rhizoma imperatae, poria, ramulus cinnamomi, malvastrum coromandelianum, solanum lyratum thunb, ramulus et folium picrasmae bark, gymbidium ensifolium roots, sargassum, verbena officinalis, gentianopsis paludosa, radix notoginseng, colla corii asini, sambucus adnata, herba lycopi, latouchea fokiensis, sinochasea trigyna, veronica serpyllifolia with insect galls, teucrium viscidum, sonchus arvensis, psychotria calocarpa kurz, rhodiola dumulosa and fructus mori. The medicine has the advantages that the medicine has functions of invigorating spleens, supplementing qi, diminishing swelling, removing dampness, replenishing blood and removing stasis, can be used for preventing and treating the piroplasmosis of the cattle and is low in cost, accordingly, the immunity of the cattle can be improved, recurrence can be prevented after the cattle is cured.

Description

technical field [0001] The invention relates to the technical field of veterinary medicines, in particular to a medicine for preventing and treating qi and blood deficiency type bovine pyrosomiasis. Background technique [0002] Bovine pyrozoosis, also known as haemosporidiosis, is a protozoan disease caused by pyrozoites parasitic in animal red blood cells and reticuloendothelial cells. The pyrophorans found in animals in my country mainly belong to the genus Babesia of Babesco and the genus Theiles of the family Thealidae. There are three species of Babesia bovis that have been reported: double-bud Babesia bovis, Babesia bovis and Babesia ovum. There are 2 species of Theileria bovine: P. annulus and Theileria thurseni. Babesia parasitizes in the erythrocytes of cattle, while P. Theileria first invades reticuloendothelial cells (mainly lymphocytes, macrophages, etc.) after infecting cattle, and then invades erythrocytes. In addition to cattle and sheep, the animals infe...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61P33/02A61K35/36
CPCA61K36/60A61K9/0019A61K9/0095A61K9/19A61K35/36A61K36/03A61K36/076A61K36/185A61K36/258A61K36/28A61K36/35A61K36/41A61K36/515A61K36/53A61K36/54A61K36/605A61K36/72A61K36/74A61K36/80A61K36/81A61K36/85A61K36/898A61K36/899A61K2300/00
Inventor 李佃场
Owner 李佃场
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