Application of paecilomyces cicadae cordyceps polysaccharides in preparation of chicken immunity enhancement reagent

A technology of cicada chinensis and immune enhancement, applied in antiviral agents, biochemical equipment and methods, medical preparations containing active ingredients, etc., can solve problems such as difficulty in generating immune responses and incomplete control of infectious diseases, and achieve Enhanced cellular immunity and humoral immunity, no hidden dangers of drug residues, and improved efficacy

Active Publication Date: 2016-06-22
ZHEJIANG SUB TROPICS CROP INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

The technical effect described by this patented technology is that it provides an effective way for animals to take advantage of their own health benefits without causing harmful substances like pesticides used during farming operations. This makes them more beneficial than other methods such as chemotherapy drugs because they don't affect humans who consume those products themselves. Additionally, Cimedium spp., which contains certain compounds found naturally within plants called Celastia fistulae (CFO), have been shown to stimulate specific cells involved in innate defense mechanisms against various diseases including viruses.

Problems solved by technology

This patented technical problem addressed in this patent relates to preventing or controllably reducing disease symptoms when administering conventional vaccinations with chemical substances like polyhydroxybutyrate injection into young livestock due to poor responses during vaccinary practices.

Method used

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  • Application of paecilomyces cicadae cordyceps polysaccharides in preparation of chicken immunity enhancement reagent
  • Application of paecilomyces cicadae cordyceps polysaccharides in preparation of chicken immunity enhancement reagent
  • Application of paecilomyces cicadae cordyceps polysaccharides in preparation of chicken immunity enhancement reagent

Examples

Experimental program
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Effect test

Embodiment 1

[0019] Example 1. Separation and Purification of a Single Component of Cicadaea Cordyceps Polysaccharide

[0020] 1.1 Extraction and preparation of polysaccharides from Cordyceps cicadae

[0021] Grind Cordyceps cicadae and pass through a 60-80 mesh sieve; add 10 times the volume of 50% ethanol to the crushed raw material, carry out hot reflux auxiliary extraction, filter, and repeat the above steps for the filter residue, repeat 1-3 times; combine multiple filtrates . Concentrate under reduced pressure at 70°C to one-tenth of the original volume; add 3 times the volume of 95% ethanol to the above concentrated solution while stirring, let it stand for more than 4 hours, and collect the precipitate by centrifugation; wash the precipitate with 3 times the volume of ethanol, centrifuge, and vacuum Dried to obtain a dark brown powdery Cordyceps polysaccharide product.

[0022] 1.2 Separation and purification of polysaccharides from Cordyceps cicadae

[0023] In the last step of...

Embodiment 2

[0024] Embodiment 2. The influence of the polysaccharide of Cicadae sinensis on chicken immunity

[0025] 2.1 Materials and methods

[0026] 2.1.1 Test animals

[0027] The chicks were reared in the poultry breeding and hatching room of Wenzhou Vocational College of Science and Technology. They were fed and drank ad libitum. Keep the feeding environment conditions of each group consistent, disinfect regularly, keep the sanitation in the house, and follow the routine feeding management.

[0028] 2.1.2 Drugs and diagnostic reagents

[0029] Cordyceps cicadae polysaccharide extract, astragalus polysaccharide (manufactured by Guangdong Tianbao Biopharmaceutical Co., Ltd.), Newcastle disease standard positive serum, negative serum and Newcastle disease virus hemagglutination inhibitory antigen (China Veterinary Drug Supervision 20140301), Newcastle disease IV series live vaccine ( Lasota strain) (virus vaccine), Newcastle disease oil emulsion inactivated vaccine (produced by Zhe...

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Abstract

The invention relates to an application of paecilomyces cicadae cordyceps polysaccharides in preparation of a chicken immunity enhancement reagent and belongs to the field of immunologic adjuvants for livestock and poultry. The paecilomyces cicadae cordyceps polysaccharides are prepared from paecilomyces cicadae sporophore or a culture medium through heat reflux extraction and later separation and purification by the aid of a ceramic membrane. The technology is simple, and immunity tests prove that the immunologic function of the chicken organisms can be remarkably improved by the immunity enhancement reagent containing the paecilomyces cicadae cordyceps polysaccharides; through matching with a new castle disease vaccine for chicken immunization, the immune response of the vaccine can be remarkably improved, the immunization lasts for a longer time, and the preparation is free of drug residues, toxic and side effects and the like, and is an environment-friendly, efficient and stable chicken immunity enhancement reagent.

Description

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Claims

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Application Information

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Owner ZHEJIANG SUB TROPICS CROP INST
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