A kind of stomach and digestion tablet and preparation method thereof

A technology for digesting tablets and tablets, which is applied in the digestive system, pill delivery, and pharmaceutical formulations. It can solve the problems of unstable transfer rate of tangeridin, uncomfortable burnt smell, and heavy product odor, and improve the bioavailability of the human body. , exert the effect of medicine, improve the effect of curative effect

Active Publication Date: 2017-03-22
JIANMIN GROUP YEKAITAI SINOPHARM (SUIZHOU) CO LTD
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0004] The disadvantage of the above process is that the composition of the medicinal materials of Pseudostellaria Pseudostellaria and Chinese yam changes during the drying process at a higher temperature (70°C to 80°C), and the color becomes darker, resulting in unpleasant burnt and bitter taste; after being crushed into fine powder (80 mesh to 120 At the same time, the finished product has a gritty feeling and poor taste, which eventually leads to heavy odor and adverse side effects such as nausea and vomiting; while the main technical parameters of the extraction-concentration process are not clear, resulting in unstable transfer rate of nobiletin , is not conducive to the efficacy of the drug

Method used

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  • A kind of stomach and digestion tablet and preparation method thereof
  • A kind of stomach and digestion tablet and preparation method thereof
  • A kind of stomach and digestion tablet and preparation method thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Embodiment 1: Chinese medicine powder fineness taste test

[0030] 1. Taste test of heterophylla heterophylla powder with different particle sizes

[0031] Test method: Take 100-mesh, 150-mesh, 200-mesh, 300-mesh, and 500-mesh Pseudostellariae powder, use 45% syrup to make a paste containing 50% crude drug powder, and then 100 volunteers tasted it and evaluated the taste. The results are shown in Table 1.

[0032] Table 1 Taste test of heterophylla heterophylla powder with different particle sizes

[0033] Mesh number (mesh) 100 150 200 300 400 Particle size (μm) 150 106 75 48 38 rough, gritty 100 56 7 0 0 More delicate, no grittiness 0 41 42 0 0 exquisite 0 3 51 16 0 delicate and smooth 0 0 0 84 100

[0034] 2. Taste test of yam powder with different particle sizes

[0035] Test method: Take yam powder of 100 mesh, 150 mesh, 200 mesh, 300 mesh, and 400 mesh, and use 45% syrup to make a paste contain...

Embodiment 2

[0039] Embodiment 2: preparation process research

[0040] 1. Experiment on drying process conditions of medicinal materials

[0041] In order to optimize the drying process conditions of Pseudostellaria Pseudostellaria and Chinese yam, Pseudostellaria Pseudostellaria and Chinese yam were dried at different temperatures for different times to observe the changes in the properties of the medicinal materials, and to check the changes in taste and water content, and make a comparative analysis.

[0042] (1) Take 500 grams of Pseudostellariae Radix, select the drying temperature and drying time for the test, and observe the changes in properties, taste and water content of Pseudostellariae Pseudostellariae. The results are shown in Tables 3 and 4.

[0043] Table 3 The effect of drying at 73℃±2℃ for different times on the quality of heterophylla

[0044]

[0045] The results showed that when dried at 73°C±2°C, Pseudostellariae Radix Pseudostellariae could be easily crushed int...

Embodiment 3

[0104] Prescription of raw materials: Pseudostellaria ginseng 228.6g, tangerine peel 22.9g, yam 171.4g, malt (fried) 171.4g, hawthorn 114.3g.

[0105] Preparation method: (1) Take yam and half the amount of heterophylla, dry at 50°C, and then use a low-temperature ultrafine pulverizer at -25°C to pulverize into a 400-mesh ultrafine powder for later use; (2) Take tangerine peel and malt (stir-fried ), hawthorn and the other half of the Radix Pseudostellariae, add 9 times of water for the first time, add 7 times of water for the second time and decoct twice, each time for 2 hours, combine the decoction, filter at a temperature of 90°C, and the filtrate is in Concentrate under reduced pressure at 65°C to a clear paste with a relative density of 1.12, dry it to make extract powder; (3) take the ultrafine powder in step (1) and the extract powder in step (2), add appropriate amount of sucrose and dextrin , compounded with a low-temperature ultrafine pulverizer for 15 minutes, press...

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Abstract

The invention provides stomach-invigorating digestion-helping tablets and a preparation method thereof.The stomach-invigorating digestion-helping tablets are prepared by using 180-280 parts of radix pseudostellariae, 18-28 parts of dried tangerine or orange peels, 135-210 parts of rhizoma dioscoreae, 135-210 parts of malt (fried) and 90-140 parts of hawthorn fruits as medicinal raw materials, smashing the rhizoma dioscoreae and a half amount of the radix pseudostellariae by using a low-temperature ultra-fine smashing machine to prepare ultra-fine powder and optimizing smashing, drying, extraction, concentration and other process parameters and molding process parameters.The stomach-invigorating digestion-helping tablets prepared by means of the preparation method have good taste, stable quality and good curative effect and compliance and is safe and free of side effects.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine preparations, in particular to a tablet with the function of invigorating the stomach and eliminating food and a preparation method thereof. Background technique [0002] Jianwei Xiaoshi Tablet is a new variety recorded in recent editions of the Chinese Pharmacopoeia, which has the effect of strengthening stomach and eliminating food. It is clinically used for food accumulation caused by weakness of the spleen and stomach. Symptoms include not thinking about eating, belching and sour smell, abdominal fullness; indigestion sees the above syndromes. Oral, can be chewed. Specifications (2) 4-6 tablets for adults, 2 tablets for children aged 2 to 4, 3 tablets for children aged 5 to 8, and 4 tablets for children aged 9 to 14; 3 times a day. Specifications (1) Adults take 3 tablets at a time, 3 times a day, children may reduce it accordingly. Its traditional prescription is: Radix heteroph...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8998A61K9/30A61P1/14
CPCA61K9/2059A61K9/28A61K36/36A61K36/734A61K36/752A61K36/8945A61K36/8998A61K2236/331A61K2236/39A61K2236/51A61K2300/00
Inventor 任平远布忠江聂一鑫刘海洋佘金燕邱冬梅叶小青沈亚娣
Owner JIANMIN GROUP YEKAITAI SINOPHARM (SUIZHOU) CO LTD
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