Thermal stable copper metal organic framework material and preparation method and application thereof

An organic framework, copper metal technology, applied in the field of tetrahydropyrrole catalyst, can solve the problems of low selectivity, low cost of raw materials, long synthesis route, etc., and achieves the effects of simple process flow, convenient preparation and good reproducibility

Active Publication Date: 2016-08-03
CHANGZHOU UNIV
View PDF2 Cites 6 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The catalyst for the cyclization reaction is expensive, and some methods have long synthetic routes, many by-products, and low yields, which do not have the value of actual industrial operation
Using tetrahydrofuran and ammonia as raw materials,

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Thermal stable copper metal organic framework material and preparation method and application thereof
  • Thermal stable copper metal organic framework material and preparation method and application thereof
  • Thermal stable copper metal organic framework material and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

experiment example 1

[0018] Preparation of Experimental Example 1 Copper Metal Organic Framework:

[0019] (I) Synthesis of 2,3,5,6-tetrafluoro-1,4-bis(chloromethyl)benzene

[0020] Add tetrafluorotere-phenylenedimethanol (10.50g, 0.05mol) to a 250mL round bottom flask, add 120mL of dichloromethane, stir until clear, add thionyl chloride (23.79g, 0.20mol) and stir until clear, reflux for 2h After rotary evaporation, 11.30 g of white solid was obtained, namely 2,3,5,6-tetrafluoro-1,4-bis(chloromethyl)benzene, with a yield of 99.59%.

[0021] (II) Synthesis of 2,3,5,6-tetrafluoro-1,4-bis(1,2,4-triazole-1-methyl)benzene

[0022] Add triazole (6.91g, 0.10mol) and anhydrous potassium carbonate (20.00g) into a 500mL four-necked flask, add 120mL acetone, stir for 30min, and dissolve 2,3,5,6 obtained in the previous step with 180mL acetone -Tetrafluoro-1,4-bis(chloromethyl)benzo was added dropwise into a four-neck flask, refluxed for 20 hours after the dropwise addition, and the solid and liquid were se...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses a thermal stable copper metal organic framework material and a preparation method and application thereof, and relates to the field of pyrrolidine catalysts. A catalyst is the thermal stable copper metal organic framework material, and the chemical formula of the thermal stable copper metal organic framework material is Cu(L)(NO3)2, wherein L represents a 2,3,5,6-tetrafluoro-1,4-bis(1,2,4-triazol-1-methyl)benzene ligand, and NO3 is nitrate anion. Cupric nitrate tetrahydrate and the organic ligand 2,3,5,6-tetrafluoro-1,4-bis(1,2,4-triazol-1-methyl)benzene are subjected to a hydrothermal reaction under an airtight condition, and the copper metal organic framework material with a two-dimensional layered structure is obtained. The synthetic method is high in yield and good in reproducibility; the obtained crystal is high in purity and thermal stability. The copper metal organic framework material has better catalytic activity on catalyzing of tetrahydrofuran gas phase amination, the conversion rate of tetrahydrofuran reaches 72%, and the selectivity of pyrrolidine reaches 90%.

Description

technical field [0001] The invention relates to the field of tetrahydropyrrole catalysts, in particular to a preparation method of a heat-stable copper metal organic framework material and an application of catalytic tetrahydrofuran gas-phase amination. Background technique [0002] Tetrahydropyrrole, also known as pyrrolidine, English name Tetrahydropyrrole or Pyrrolidine, molecular formula C 4 h 9 N, boiling point 87°C, density 0.852gcm –3 , as a cyclic secondary amine, pK b =2.9, it has general amine properties and has extremely wide uses in many aspects. In the field of drug synthesis, there are many kinds of drugs directly having a tetrahydropyrrole structure in the structure, such as buflomedil for treating cerebrovascular disorders, dexmorphilamide tartrate with analgesic function, and procyclone for anti-parkinsonia The anti-infective drug pirromid, the local anesthetic pirrocaine, the depression drug fenprofen and so on. In addition, tetrahydropyrrole is also w...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): C07F1/08B01J31/22C07D295/023C07D295/027
CPCB01J31/2217B01J2531/0238B01J2540/22B01J2540/40C07D295/023C07D295/027C07F1/08
Inventor 陈圣春陆胜男田锋钱俊峰何明阳陈群
Owner CHANGZHOU UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap