Pharmaceutical composition for inhibiting tumor angiogenesis and preparation method of pharmaceutical composition

Abstract

The invention belongs to the field of medicine, and in particular relates to a pharmaceutical composition for inhibiting tumor angiogenesis and a preparation method of the pharmaceutical composition. The pharmaceutical composition, which is prepared from such medicinal raw materials as turtle shell or turtle shell processed with vinegar and uniflower swisscentaury root, in coordination with pericarpium citri reticulatae viride (or pericarpium citri reticulatae viride processed with vinegar) or flos chrysanthemi indici, is used for inhibiting the tumor angiogenesis; the pharmaceutical composition is capable of effectively inhibiting tumor growth; and the pharmaceutical composition has a good medicinal value; therefore, a new choice is provided for clinical use.

Description

technical field

[0001] The invention belongs to the field of medicine, and in particular relates to a pharmaceutical composition for inhibiting neovascularization of tumors and a preparation method thereof. Background technique

[0002] Angiogenesis is the process of sprouting new blood vessels from existing ones. This process is associated with migration and proliferation of vascular endothelial cells. The process of embryonic development is accompanied by angiogenesis. However, apart from wound healing, the female menstrual period, and some pathological processes (such as cancer), angiogenesis rarely occurs in adults.

[0003] Angiogenesis plays an extremely important role in the growth, metastasis and prognosis of malignant solid tumors. Angiogenesis is required for the further growth of malignant solid tumors beyond the epithelial basement membrane. The newly formed blood vessels in the tumor have their own unique structural characteristics, which are characterized b...

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