Combined drug-resistant bacterium immunoreactive protein, and preparation method and application thereof

Abstract

The invention relates to a combined drug-resistant bacterium immunoreactive protein, and a preparation method and application thereof. The combined drug-resistant bacterium immunoreactive protein is characterized in that a plurality of drug-resistant pathogenic bacteria are used as raw materials and subjected to culture and amplification, sterilization and concentration, detoxification and wall breaking, extraction of the cell walls, cell membranes and capsules of the bacteria and synthesis of a combined drug-resistant bacterium immunoreactive protein biological product. The drug-resistant pathogenic bacteria comprise one or a mixture of two selected from a group consisting of Pseudomonas aeruginosa and Pseudomonas maltophila and a mixture of two or more selected from a group consisting of Klebsiella pneumonia, Haemophilus influenza, Acinetobacter baumannii, Staphylococcus aureus, Neisseria meningitidis, Mycobacterium tuberculosis, Escherichia coli and Staphylococcus albus. The combined drug-resistant bacterium immunoreactive protein provided by the invention is used for preparing preparations applicable to human mucosal absorption, mainly including nasal drops, oral liquid, tablets, electuary, injections and throat sprays. The combined drug-resistant bacterium immunoreactive protein can overcome the problems that drug-resistant bacteria continuously increase and threaten the health of mankind and animals.

Description

technical field [0001] The invention relates to a multi-drug-resistant bacterial immune active protein and its preparation method and application. It belongs to the technical field of biopharmaceuticals. Background technique [0002] It is well known that pathogenic bacteria are extremely harmful to human health. Antibiotics have a healing effect that doubles the lifespan of human beings. However, with the prolonged use of antibiotics, the drug resistance of pathogenic bacteria increases, and the rapid growth of drug-causing bacteria reduces the antibacterial efficacy of antibiotics. At present, the widespread occurrence of bacterial drug resistance around the world is on the rise, threatening the health of humans and animals. The consequences of drug-resistant bacterial infection are serious, including protracted course of disease, prolonged hospitalization, increased mortality, and increased hospitalization costs. Bacterial resistance not only threatens health, but als...

AI Technical Summary

Problems solved by technology

[0005] One of the purposes of the present invention is to provide a multidrug-resistant bacterial immune activity protein in order to solve the problem that bacterial drug resistance is continuously increasing and threatens the health of humans and animals.