Medicine for treating impotence and preparation method thereof

A drug and impotence technology, applied in the direction of drug combination, pharmaceutical formula, plant raw materials, etc., can solve the problems of adverse reactions, adverse drug reactions, unfavorable direct use, etc., and achieve the effect of taking safety.

Inactive Publication Date: 2016-10-26
江苏秀宇生物医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But western medicine generally has the following problems: (1) although western medicine has the advantage of quick onset, it treats the symptoms but not the root cause, most of them are temporary medication, short-term onset, and often appear after drug withdrawal, impotence is more serious phenomenon; (2) ) The drugs used have obvious adverse reactions, and the drugs that regulate the central nervous system are prone to dependence. For example, the popular sildenol citrate (Viagra) in recent years has been reported to have obvious adverse reactions after medication.
In the motherland's medical treasure house, a large amount of clinical experience in the treatment of such diseases has been accumulated. They treat both symptoms and root causes, and some of them have good therapeutic effects in certain aspects. Unfortunately, most of them are still in the state of traditional Chinese medicine prescriptions, so they are not conducive to direct administration.
As far as Chinese patent medicines are concerned, at present, only a few varieties such as Nanbao Capsules and Yishen Xingyang Capsules are commonly used clinically, which is obviously far from enough

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Embodiment 1, the medicine of the present invention and its preparation.

[0024] Raw material prescription: silkworm moth 900-960 parts, epimedium 510-550 parts, rehmannia glutinosa 300-360 parts, wine fried angelica 240-280 parts, fried dodder 240-280 parts, fried Eucommia 240-280 parts, yam 240- 280 parts, 140-180 parts of deer horn glue.

[0025] Preparation method: After weighing the raw material drug according to the weight of the raw material drug formula, it is completed through the following steps:

[0026] (1) Silkworm moths are crushed into coarse powder, add 7-9 times the amount of 95% ethanol, soak for 7-9 hours, reflux extraction for 1 hour, add 5-7 times the amount of ethanol, reflux extraction for 1 hour, combine the extracts, filter , Ethanol was recovered under reduced pressure until there was no ethanol smell, and the filtrate was obtained.

[0027] (2) Angelica is crushed into coarse particles, refluxed with Epimedium plus 50% ethanol for 8-10 time...

Embodiment 2

[0030] Example 2, the preferred preparation method of the medicament of the present invention.

[0031] Raw material prescription: 908 parts of silkworm moth, 518.8 parts of epimedium, 324.3 parts of Rehmannia glutinosa, 259.4 parts of fried angelica, 259.4 parts of fried dodder, 259.4 parts of fried Eucommia, 259.4 parts of yam, 162.1 parts of deer horn glue.

[0032] Preparation method: After weighing the raw material drug according to the weight of the raw material drug formula, it is completed through the following steps:

[0033] (1) Silkworm moths are crushed into coarse powder, add 8 times the amount of 95% ethanol, soak for 8 hours, reflux extraction for 1 hour, add 6 times the amount of ethanol, reflux extraction for 1 hour, combine the extracts, filter, and recover the ethanol under reduced pressure to No ethanol smell, the filtrate was obtained;

[0034] (2) Angelica sinensis is crushed into coarse particles, and Epimedium plus 50% ethanol is refluxed and extracted...

Embodiment 3

[0037] Embodiment 3, the concentrated pill medicine of the present invention and its preparation.

[0038] Raw material prescription: silkworm moth 908g, epimedium 518.8g, rehmannia glutinosa 324.3g, wine fried angelica 259.4g, fried dodder 259.4g, fried eucommia 259.4g, yam 259.4g, antler glue 162.1g.

[0039] Preparation method: carry out the same steps as (1), (2) and (3) of Example 2 after weighing the raw material drug according to the proportioning weight of the raw material drug composition, and then:

[0040] (4) Deer horn gum and yam are crushed into fine powder, mixed with the fine powder of the aforementioned step (3) and an appropriate amount of starch, then mixed with the filtrate of step (1), added with water to make a soft material, pelletized, dried, and oxidized Iron-coloured sugar coating, dried, made into 1000 g concentrated pellets.

[0041] The medicine of the present invention has the effects of warming and tonifying kidney yang, nourishing blood and rep...

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PUM

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Abstract

Disclosed are medicine for treating impotence and a preparation method thereof. The medicine is prepared from active pharmaceutical ingredients including, by weight, 900-960 parts of silkworm moth, 510-550 parts of Herbe epimedii, 300-360 parts of Radix rehmanniae preparata, 240-280 parts of Chinese angelica fried with wine, 240-280 parts of fried Semen cuscutae, 240-280 parts of fried Cortex eucommia, 240-280 parts of Chinese yam and 140-180 parts of Colla cornus cervi. The preparation method includes: smashing silkworm moth into powder, adding 95% alcohol for soaking, and obtaining filtrate through backflow extraction; smashing Chinese angelica into granules, adding 50% alcohol into Herba epimedii, performing backflow extraction and concentration to form clear paste a; slicing Radix rehmanniae preparata, adding water into Semen cuscutae and Cortex eucommia, soaking, decocting, filtering, and concentrating to form clear paste b; combining the clear paste a with the clear paste b, mixing well, drying, and smashing into fine powder; smashing Colla cornus cervi and Chinese yam into fine powder, mixing the fine powder well with the above-mentioned fine powder and a proper amount of starch, mixing well with the above-mentioned filtrate, and making a mixture into tablets, capsules or pills. The medicine has efficacy of warming and tonifying kidney-yang and nourishing blood and replenishing sperm and is mainly used for syptoms like kidney-yang insufficiency, impotence, spermatorrhea, fear of cold and cold limbs and soreness and weakness of waist and knees.

Description

Technical field: [0001] The invention belongs to the technical field of traditional Chinese medicine preparations, and relates to a medicine for treating impotence and a preparation method thereof. Background technique: [0002] Impotence (ED) is a common disease in andrology. According to statistics, the incidence of ED in different degrees of 40-70-year-old American men is 52%, and the incidence of impotence in my country is also quite high. The methods commonly used in western medicine to treat impotence include hormone therapy, drug therapy and surgical therapy. Among them, oral drugs can be divided into two categories: central drug and peripheral drug. Another non-invasive treatment is to treat through the skin or urethral mucosa: ED external drugs applied to the skin of the penis include nitroglycerin patch or emulsion, prostate E1 emulsion, minoxidil emulsion, etc.; drugs for the treatment of ED through the urethra include: Alprostadil etc. Oral sildenamol citrate ...

Claims

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Application Information

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IPC IPC(8): A61K36/8945A61P15/10A61K35/32A61K35/64
CPCA61K36/8945A61K35/32A61K35/63A61K36/232A61K36/296A61K36/39A61K36/43A61K36/46A61K36/804A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2300/00
Inventor 何占畏
Owner 江苏秀宇生物医药科技有限公司
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