Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

A kind of active substrate with surface-enhanced Raman effect and its preparation method and application

A surface-enhanced Raman and active substrate technology, applied in Raman scattering, coatings, instruments, etc., can solve the problems of poor chemical stability of substrates, inability to store for a long time, and complicated preparation methods, and achieve good stability, Uniform distribution and good stability

Active Publication Date: 2018-02-13
SHENZHEN INST OF ADVANCED TECH
View PDF3 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, silver is a SERS substrate that is extremely easy to oxidize and vulcanize, and cannot be stored for a long time, and the method for making printing ink in this patent is complicated, and it is necessary to add glucose, polyvinylpyrrolidone, and ethylene glycol to adjust the viscosity and other properties of the ink. , the preparation method is cumbersome, and the chemical stability of the substrate is not good

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A kind of active substrate with surface-enhanced Raman effect and its preparation method and application
  • A kind of active substrate with surface-enhanced Raman effect and its preparation method and application
  • A kind of active substrate with surface-enhanced Raman effect and its preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0059] A preparation method of an active substrate (abbreviated as SERS active substrate) with a surface-enhanced Raman effect (the preparation flow chart of the method is as follows figure 1 shown), including the following steps:

[0060] (1) Utilize the seed growth method to prepare the aqueous solution of the gold nanorods modified by cetyltrimethylammonium bromide (CTAB), specifically as follows:

[0061] a. Synthesis of gold seeds: Dissolve 5mL of 0.5M chloroauric acid in 5mL of 0.2M cationic surfactant CTAB solution, mix well, add 0.6mL of newly configured, pre-cooled 0.01M sodium borohydride solution Quickly add to the above solution, and vigorously mix for 2 minutes, then place at room temperature 25°C for 2 hours to obtain gold seed solution;

[0062] b, the configuration of the growth solution of gold nanorods: add the silver nitrate of 0.225mL, 0.1M, the chloroauric acid solution of 18mL, 5mM in the CTAB solution of 90mL, 0.2M, then add the ascorbic acid solution o...

Embodiment 2

[0070] A preparation method for a SERS active substrate, comprising the following steps:

[0071] (1) The aqueous solution of gold nanorods modified by cetyltrimethylammonium bromide (CTAB) was prepared by using the gold seed growth method. stick primary dispersion;

[0072] (2) Centrifuge and concentrate the gold nanorod primary dispersion, the centrifugal speed is 9000rpm, and the centrifugation time is 10min, remove 80% of the supernatant, take the lower layer of high-concentration gold nanorods and disperse them into an appropriate volume. In ionized water, the concentrated concentration obtained is 6nmol / L gold nanorod sol, that is, high-concentration gold nanorod printing ink;

[0073] (3) The rest of the operation steps are basically the same as in Example 1, except that the diameter of the round hole of the screen printing screen is 3mm, and it is evenly distributed in the form of 5 rows×5 columns, and 3 layers of gold nanometers are printed on the PLLA electrospun fi...

Embodiment 3

[0075] A preparation method for a SERS active substrate, comprising the following steps:

[0076] (1) The preparation of the gold nanorod primary dispersion is the same as in Example 1, and the gold nanorod primary dispersion with a concentration of 0.3nmol / L is obtained;

[0077] (2) Centrifuge and concentrate the gold nanorod primary dispersion, the centrifugal speed is 10000rpm, the centrifugation time is 7min, remove 90% of the supernatant, take the lower layer of high-concentration gold nanorods and disperse them into an appropriate volume. In ionized water, the concentrated concentration obtained is 15nmol / L gold nanorod sol, i.e. high-concentration gold nanorod printing ink;

[0078](3) The rest of the operation steps are basically the same as in Example 1, except that the diameter of the round hole of the screen printing screen is 2 mm, and it is evenly distributed in the form of 4 rows × 5 columns, and 7 layers of gold nanometers are printed on the PLLA electrospun fi...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
lengthaaaaaaaaaa
diameteraaaaaaaaaa
diameteraaaaaaaaaa
Login to View More

Abstract

The invention discloses a preparation method of an active substrate (abbreviated as SERS active substrate) with a surface reinforced Raman effect. The method comprises the following steps: gold nanorod water solution modified by hexadecyl trimethyl ammonium bromide is prepared, and is centrifugally concentrated to obtain gold nanorod sol with a concentration of 6-30 nmol / L, namely high-concentration gold nanorod printing ink; and the high-concentration gold nanorod printing ink is printed on a bearing material with negative electricity, and is naturally dried to obtain the SERS active substrate. The preparation method of the SERS active substrate is simple in operation and mild in conditions, and facilitates simple, fast and batch production of the SERS active substrate; and the SERS substrate is high in chemical stability, regular in structure and low in cost. The invention further provides the SERS active substrate and application thereof.

Description

technical field [0001] The invention relates to the technical field of surface-enhanced Raman spectroscopy, in particular to an active substrate with a surface-enhanced Raman effect and a preparation method and application thereof. Background technique [0002] Surface-enhanced Raman Scattering (Surface-enhanced Raman Scattering, SERS) spectroscopy has the advantages of good selectivity, high sensitivity, and sensitivity to certain molecules that are millions of times higher than conventional Raman spectroscopy. It has been used in chemistry, biology, and pharmacology. It has been widely used in various fields such as science. SERS is mainly an abnormal optical enhancement phenomenon of nanoscale rough surfaces or particle systems, which can amplify the Raman signals of molecules adsorbed on the surface of materials by 10 6 -10 14 times. Therefore, for SERS detection and analysis technology, the preparation of SERS active substrate with good performance is the prerequisit...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): C23C24/00G01N21/65
CPCC23C24/00G01N21/65G01N21/658
Inventor 喻学锋唐思莹李鹏辉李泳
Owner SHENZHEN INST OF ADVANCED TECH
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com