Pharmaceutical composition for treating swine dysentery

A composition and technology for swine dysentery, applied in the directions of drug combinations, active ingredients of heterocyclic compounds, pharmaceutical formulations, etc., can solve the problems of antibiotic resistance and high antibiotic residues, and achieve convenient portability, no toxic side effects, and stable effects. Effect

Inactive Publication Date: 2017-05-10
郑州莉迪亚医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although this drug treatment has a certain effect, the problem is that the residual amount of antibiotics is high

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] A pharmaceutical composition for treating swine dysentery, the main raw materials in parts by weight are: 5 parts of 9-nitrocamptothecin, 2 parts of toosendanin, 9 parts of evodialide, 25 parts of gomisin G, topoxetine hydrochloride 15 parts of Kang, 2 parts of 11-keto-boswellic acid, 6 parts of methyl ophiopogon flavanone B, 0.5 parts of epoxy sucrose alcohol, 8 parts of isoforsythiaside, and 2 parts of taraconitamine.

[0016] A preparation method of a pharmaceutical composition for treating swine dysentery, the specific steps are:

[0017] First, in a pharmaceutical-grade clean area, weigh 9-nitrocamptothecin, toosendanin, rutaecarlide, gomisin G, topotecan hydrochloride, 11-ketoboswellic acid, methyl Ophiopogon japonicus flavanone B, epoxy caperin alcohol, isoforsythiaside, and taraconitamine, sieved, mechanically mixed, added ultrapure water, placed in a pharmaceutical mixer, mixed for 4 minutes, and controlled RSD≤ 5%, mixed, pressed into tablets and dried at low...

Embodiment 2

[0019] A pharmaceutical composition for treating swine dysentery, the main raw materials in parts by weight are: 8 parts of 9-nitrocamptothecin, 3 parts of toosendanin, 9 parts of rutaecaractone, 28 parts of gomisin G, topoxetine hydrochloride 18 parts of Kang, 2 parts of 11-keto-boswellic acid, 6 parts of methyl ophiopogon flavanone B, 0.5 parts of epoxy sucrose alcohol, 8 parts of isoforsythiaside, and 2 parts of taraconitamine.

[0020] A preparation method of a pharmaceutical composition for treating swine dysentery, the specific steps are:

[0021] First, in a pharmaceutical-grade clean area, weigh 9-nitrocamptothecin, toosendanin, rutaecarlide, gomisin G, topotecan hydrochloride, 11-ketoboswellic acid, methyl Ophiopogon japonicus flavanone B, epoxy caperin alcohol, isoforsythiaside, and taraconitamine, sieved, mechanically mixed, added ultrapure water, placed in a pharmaceutical mixer, mixed for 4 minutes, and controlled RSD≤ 5%, mixed, pressed into tablets and dried at...

Embodiment 3

[0023] A pharmaceutical composition for treating swine dysentery, the main raw materials in parts by weight are: 10 parts of 9-nitrocamptothecin, 4 parts of toosendanin, 10 parts of rutaecaractone, 29 parts of gomisin G, topoxetine hydrochloride 19 parts of Kang, 3 parts of 11-keto-boswellic acid, 8 parts of methyl ophiopogon flavanone B, 0.9 parts of epoxy sucrose alcohol, 9 parts of isoforsythiaside, and 3 parts of taraconitamine.

[0024] A preparation method of a pharmaceutical composition for treating swine dysentery, the specific steps are:

[0025] First, in a pharmaceutical-grade clean area, weigh 9-nitrocamptothecin, toosendanin, rutaecarlide, gomisin G, topotecan hydrochloride, 11-ketoboswellic acid, methyl Ophiopogon japonicus flavanone B, epoxy caperin alcohol, isoforsythiaside, and taraconitamine, sieved, mechanically mixed, added ultrapure water, placed in a pharmaceutical mixer, mixed for 6 minutes, and controlled RSD≤ 5%, mixed, pressed into tablets and dried ...

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PUM

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Abstract

The invention discloses pharmaceutical composition for treating swine dysentery. The pharmaceutical composition for treating the swine dysentery is prepared from main raw materials in parts by weight as follows; 5-16 parts of 9-nitro camptothecin, 2-6 parts of toosendanin, 9-10 parts of evodine, 25-32 parts of gomisin, 15-23 parts of topotecan hydrochloride, 2-4 parts of 11-keto-boswellic acid, 6-10 parts of methylophiopogonanone B, 0.5-1.4 parts of epoxylathyrol, 8-9 parts of isoforsythiaside and 2-4 parts of talatisamine. The components of raw materials of the medicine are strictly selected according to the knowledge mechanism of the swine dysentery, so that the purpose of comprehensive recovery is achieved, and the composition has the characteristics of taking effect quickly, acting stably, being convenient to carry and take and having no toxic and side effects after being taken for a long time.

Description

technical field [0001] The invention relates to the field of medicine preparation, in particular to a pharmaceutical composition for treating swine dysentery. Background technique [0002] Swine dysentery, also known as swine blood dysentery, is a serious intestinal infectious disease caused by Treponema hyodysenteriae. The main clinical symptoms are severe mucous hemorrhagic diarrhea. Chronic mucus diarrhea is the main period. The autopsy pathological features were catarrhal, hemorrhagic and necrotic inflammation in the large intestine mucosa. Under natural circumstances, only pigs are sick, and pigs of various ages and varieties can be infected, but the main damage is 2-3 month-old piglets; the morbidity and mortality of young pigs are higher than that of large pigs; sick pigs and Carriers are the main source of infection, and the occurrence of the disease has no obvious seasonality; due to the existence of carrier pigs, the disease is often spread by mobilizing pigs and...

Claims

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Application Information

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IPC IPC(8): A61K31/7032A61K31/58A61K31/585A61K31/36A61K31/4745A61K31/56A61K31/353A61K31/336A61K31/439A61P1/12
CPCA61K31/7032A61K31/336A61K31/353A61K31/36A61K31/439A61K31/4745A61K31/56A61K31/58A61K31/585A61K2300/00
Inventor 不公告发明人
Owner 郑州莉迪亚医药科技有限公司
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