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Pharmaceutical composition for treating optic atrophy

A technology of optic atrophy and composition, which is applied in the direction of drug combination, nervous system diseases, active ingredients of heterocyclic compounds, etc., and can solve problems such as optic atrophy and loss of function

Inactive Publication Date: 2017-05-10
JINAN HAOYU QINGTIAN PHARMA TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But if necrosis occurs, it will cause permanent atrophy of the optic nerve and loss of related functions at the same time

Method used

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  • Pharmaceutical composition for treating optic atrophy

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Effect test

Embodiment 1

[0037] Embodiment 1: The pharmaceutical composition and preparation method thereof for the treatment of optic atrophy

[0038] The composition and parts by weight of the crude drug of the pharmaceutical composition for treating optic atrophy are: 484g of Sanzuanfeng, 266g of Herbal Triangle Maple, 45g of Asarin, 35g of Genistin, and 9g of Hederagenin;

[0039] Preparation:

[0040] (1) According to the ratio of raw materials, take Sanzuanfeng, herbal triangular maple, asarin, genistin, and hedera saponin, mix them evenly, use ethanol with a concentration of 42% by weight as a solvent, and extract by warm soaking at 32°C. The number of extractions is 9 times, each extraction time is 38 hours, and the amount of solvent used each time is 37 times the total weight of the raw material drug, filtered to obtain medicinal residue A and extract A, extract A reclaims ethanol, and concentrates to a relative density of 1.06 , filtered, the medicinal solution passes through the HPD750 mac...

Embodiment 2

[0043] Embodiment 2: the pharmaceutical composition and preparation method thereof for the treatment of optic atrophy

[0044] The composition and parts by weight of the crude drug of the pharmaceutical composition for treating optic atrophy are: 481g of Sanzuanfeng, 268g of Herbal Triangle Maple, 42g of Asarin, 36g of Genistin, and 8g of Hederagenin;

[0045] Preparation:

[0046] (1) According to the ratio of raw materials, take Sanzuanfeng, herbal triangular maple, asarin, genistin, and hedera saponin, mix them evenly, use ethanol with a concentration of 42% by weight as a solvent, and extract by warm soaking at 32°C. The number of extractions is 9 times, each extraction time is 38 hours, and the amount of solvent used each time is 37 times the total weight of the raw material drug, filtered to obtain medicinal residue A and extract A, extract A reclaims ethanol, and concentrates to a relative density of 1.06 , filtered, the medicinal solution passes through the HPD750 mac...

Embodiment 3

[0049] Embodiment 3: the pharmaceutical composition and preparation method thereof for the treatment of optic atrophy

[0050] The composition and parts by weight of the crude drug of the pharmaceutical composition for treating optic atrophy are: 487g of Sanzuanfeng, 264g of Herbal Triangle Maple, 48g of Asarin, 34g of Genistin, and 10g of Hederagenin;

[0051] Preparation:

[0052] (1) According to the ratio of raw materials, take Sanzuanfeng, herbal triangular maple, asarin, genistin, and hedera saponin, mix them evenly, use ethanol with a concentration of 42% by weight as a solvent, and extract by warm soaking at 32°C. The number of extractions is 9 times, each extraction time is 38 hours, and the amount of solvent used each time is 37 times the total weight of the raw material drug, filtered to obtain medicinal residue A and extract A, extract A reclaims ethanol, and concentrates to a relative density of 1.06 , filtered, the medicinal solution passes through the HPD750 ma...

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Abstract

The invention discloses a pharmaceutical composition for treating optic atrophy and a preparation method thereof. The pharmaceutical composition is prepared from bark of Japanese spicebush, Szechwan-Yunnan sanicle herb, asarinin, genistin, and hederagenin according to a ratio; the pharmaceutical composition may be made into various forms of drug according to conventional pharmaceutical processes to treat optic atrophy significantly.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a pharmaceutical composition for treating optic atrophy and a preparation method thereof. Background technique [0002] Optic atrophy is the pathology of retinal ganglion cells and their axons under the action of certain diseases or pathogenic factors, and eventually the entire optic nerve becomes thinner. In terms of ophthalmic treatment, optic atrophy caused by ocular contusion is one of the difficult diseases, and it is a relatively common clinical disease. Currently, there is no special treatment for it. Especially for patients with a long time after injury, it has little curative effect. [0003] Among the various causes of blindness, ocular trauma occupies a major position. When the orbit is fractured under the action of external force or the eyeball is compressed under the action of blunt force such as bruise or boxing injury, causing re...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/54A61P27/02A61P25/02A61K31/56A61K31/36A61K31/7048
CPCA61K36/54A61K31/36A61K31/56A61K31/7048A61K36/23A61K2236/333A61K2236/39A61K2236/51A61K2236/55
Inventor 不公告发明人
Owner JINAN HAOYU QINGTIAN PHARMA TECH CO LTD
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