Insomnia control pharmaceutical composition

A technology of composition and medicine, which is applied in the field of pharmaceutical composition for preventing and treating insomnia and its preparation, and can solve problems such as large differences in experimental results, few human studies, and no uniform standards for experimental conditions

Inactive Publication Date: 2017-05-24
JINAN HAOYU QINGTIAN PHARMA TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, on the whole, the current experimental research methods for Chinese herbal extracts are not unified, and there is no unified standard for experimental conditions, which makes the experimental results quite different. In addition, most of the experimental studies on Chinese herbal extracts for treating insomnia are animal experiments. There are few human studies; and because of the uncertainty of the cause of insomnia, the credibility of the current insomnia animal models still needs to be investigated; although animal experiments have shown the effectiveness of traditional Chinese medicine extracts on the one hand, relevant clinical research is still needed. Its safety can be clarified; because the factors of insomnia are closely related to the environment, spirit, emotion, etc., in clinical observation and research, there is little control on this aspect, and there is a lack of exact standards and perfect plans. The findings are not convincing

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  • Insomnia control pharmaceutical composition

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] Embodiment 1: the pharmaceutical composition for preventing and treating insomnia and preparation method thereof

[0039] The composition and parts by weight of the raw materials of the pharmaceutical composition for preventing and treating insomnia are: 535g of japonica, 528g of Zima, 515g of Zijinsha, 18g of cucurbitacin C, 12g of cucurbitacin L12g, and 8g of cycloartanol;

[0040] Preparation:

[0041] (1) According to the ratio of raw materials, take purple hemp, purple golden sand, golden vanilla, cucurbitacin C, cucurbitacin L, and cycloartanol, mix them evenly, use ethanol with a concentration of 27% by weight as a solvent, and soak at 45°C Extraction, the number of extractions is 12 times, each extraction time is 1.3 hours, each solvent consumption is 13.5 times of the total weight of the raw material drug, filtered to obtain medicinal residue A and extract A, extract A reclaims ethanol, concentrates to a relative Density 1.07, filtered, the drug solution passe...

Embodiment 2

[0044] Embodiment 2: the pharmaceutical composition for preventing and treating insomnia and preparation method thereof

[0045] The composition and parts by weight of the raw material drug of the pharmaceutical composition for preventing and treating insomnia are: 530g of Jinxiangcao, 530g of Zima, 510g of Zijinsha, 20g of cucurbitacin C, 10g of cucurbitacin L, and 9g of cycloartanol;

[0046] Preparation:

[0047] (1) According to the ratio of raw materials, take purple hemp, purple golden sand, golden vanilla, cucurbitacin C, cucurbitacin L, and cycloartanol, mix them evenly, use ethanol with a concentration of 27% by weight as a solvent, and soak at 45°C Extraction, the number of extractions is 12 times, each extraction time is 1.3 hours, each solvent consumption is 13.5 times of the total weight of the raw material drug, filtered to obtain medicinal residue A and extract A, extract A reclaims ethanol, concentrates to a relative Density 1.07, filtered, the drug solution p...

Embodiment 3

[0050] Embodiment 3: the pharmaceutical composition for preventing and treating insomnia and preparation method thereof

[0051] The composition and parts by weight of the raw material drug of the pharmaceutical composition for preventing and treating insomnia are: 540g of Kamba herb, 525g of Zima, 520g of Zijinsha, 15g of cucurbitacin C, 13g of cucurbitacin L, and 6g of cycloartanol;

[0052] Preparation:

[0053] (1) According to the ratio of raw materials, take purple hemp, purple golden sand, golden vanilla, cucurbitacin C, cucurbitacin L, and cycloartanol, mix them evenly, use ethanol with a concentration of 27% by weight as a solvent, and soak at 45°C Extraction, the number of extractions is 12 times, each extraction time is 1.3 hours, each solvent consumption is 13.5 times of the total weight of the raw material drug, filtered to obtain medicinal residue A and extract A, extract A reclaims ethanol, concentrates to a relative Density 1.07, filtered, the drug solution pa...

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Abstract

The invention discloses an insomnia control pharmaceutical composition and a preparation method thereof. The pharmaceutical composition is prepared by matching active pharmaceutical ingredients phyllagathis cavaleriei, oreocnide frutescens, pternopetalii radix, cucurbitacin C, cucurbitacin L and cycloartanol and can be made into various dosage forms by conventional preparation technology and realizes a remarkable insomnia control effect.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a pharmaceutical composition for preventing and treating insomnia and a preparation method thereof. Background technique [0002] Sleep is a physiological behavior and an important condition for ensuring physical and mental health. Long-term insomnia will bring huge physical and mental damage to patients, seriously affecting people's life and work. Due to the influence of various factors, the phenomenon of sleep disturbance and lack of sleep is more and more common. At present, the most commonly used method for treating sleep disorders is to use chemically synthesized sedative-hypnotics, which will lead to dependence or addiction if taken for a long time. Clinical experience has proved that traditional Chinese medicine and its compound have unique curative effects on improving sleep, and have fewer adverse reactions. In recent years, domestic ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/23A61P25/20A61K31/575A61K31/56
CPCA61K36/23A61K31/56A61K31/575A61K36/185A61K2236/333A61K2236/39A61K2236/51A61K2236/55
Inventor 不公告发明人
Owner JINAN HAOYU QINGTIAN PHARMA TECH CO LTD
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