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Prostatic cancer computer-assisted detection method and system based on multi-parameter MRI

A computer-aided, prostate cancer technology, applied in the field of medical image processing, can solve the problems of a large number of pixels, difficult segmentation of the prostate region, and inability to describe the whole picture of the diseased region.

Active Publication Date: 2017-05-31
SOUTH CENTRAL UNIVERSITY FOR NATIONALITIES
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Problems solved by technology

[0006] At present, there are some methods to extract pixel features. These methods generally use the statistical features in the local window centered on a certain pixel as the feature of the point. The disadvantage of these methods is that the number of pixels is large, which will cause the amount of training data. Too large, and the pixel features used cannot describe the whole picture of the lesion area, which is not easy to be understood by doctors like regional features
Other methods extract features of lesion candidate areas, such as size, shape, texture, and asymmetry. The disadvantage is that the segmentation of the prostate area itself is a difficult problem, and cancer lesions in the prostate area also require experienced experts. Doctors manually segment to obtain, and at the same time, more effective features are needed to describe the lesion area of ​​prostate cancer

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Embodiment Construction

[0089] The present invention will be further described in detail below in conjunction with the accompanying drawings and specific embodiments.

[0090] see figure 1 As shown, the embodiment of the present invention provides a computer-aided detection method for prostate cancer based on multi-parameter MRI, comprising the following steps:

[0091] A. Training phase

[0092] A1, three kinds of MRI sequences I for each case in the training set T2 , I DWI , I ADC are preprocessed separately so that I T2 , I DWI , I ADC same resolution and size, I T2 , I DWI , I ADC The pixels at the same position in roughly correspond to the same part in the human body;

[0093] The set containing all cases is divided into training set and test set. Each case in the set contains three MRI sequences: T2WI, DWI, ADC (Apparent Diffusion Coefficient, apparent diffusion coefficient), where ADC is calculated by DWI, The three MRI sequences T2WI, DWI, and ADC in the same case are denoted as I ...

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Abstract

The invention discloses a prostatic cancer computer-assisted detection method and system based on multi-parameter MRI and relates to the field of medical image processing. The method includes the following steps that at a training stage, firstly, a clinical case sample is preprocessed, then a prostate region and a focus candidate region are automatically extracted, and then features of the focus candidate region are calculated and used for training a classifier; at a testing stage, the trained classier is used for classifying the features of the focus candidate region automatically extracted from the tested clinical case sample, and a corresponding diagnosis result is obtained and serves as reference comments to be provided for doctors. A series of quantitative indexes and corresponding malignancy probability values are provided for radiologists, and the doctors can be effectively assisted in diagnosing the prostatic cancer through an MRI image.

Description

technical field [0001] The invention relates to the field of medical image processing, in particular to a method and system for computer-aided detection of prostate cancer based on multi-parameter MRI. Background technique [0002] PCa (Prostate Cancer, prostate cancer) is the second most common cancer in men in the world. In the United States, about 1 / 6 men will get prostate cancer, and 1 / 36 men will die from this disease. At present, the diagnostic methods for prostate cancer include: TRUS (Trans-rectal Ultrasound, ultrasound-guided transrectal) prostate biopsy and PSA (Prostate-specific Antigen, prostate-specific antigen) serum examination. A prostate biopsy can be very uncomfortable for the patient and serious infections can occur. Prostate-specific antigen is specific to prostate tissue, but not to prostate cancer. There is considerable overlap in serum PSA results between prostate cancer and benign prostatic hyperplasia. [0003] Different from the above two methods,...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G06F19/00G06T7/11G06T7/136
CPCG06T2207/10088G06T2207/20081G06T2207/30081G16H50/20
Inventor 谌先敢刘海华陆雪松高智勇李旭
Owner SOUTH CENTRAL UNIVERSITY FOR NATIONALITIES
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