Microfluidic chip and droplet generation device applying same

Abstract

The invention provides a microfluidic chip and a droplet generation device applying the same. The microfluidic chip of a T-shaped structure comprises a continuous-phase inlet portion, a dispersion-phase inlet portion and a droplet outlet portion, wherein the continuous-phase inlet portion is a straight-through portion of the T-shaped structure, and a continuous-phase passage is formed inside the straight-through portion; the dispersion-phase inlet portion is a bypass portion of the T-shaped structure, and a dispersion-phase passage is formed in the bypass portion; the droplet outlet portion is another straight-through portion of the T-shaped structure, and a droplet passage is formed in the droplet outlet portion; the continuous-phase passage, the dispersion-phase passage and the droplet passage converge in the microfluidic chip, and a conical passage is formed on one side, close to the droplet passage, of the convergence position. The microfluidic chip has the advantage that the small-scale conical passage exists on the lower downstream of a main passage, and when a continuous phase flows through the conical passage, more shear force can be generated, so that droplets with the diameters below 100 micrometers can be generated easily.

Description

technical field [0001] The invention relates to the field of microfluidic technology, in particular to a microfluidic chip and a microdroplet generating device using the chip. Background technique [0002] Micro-droplet (Droplet) is a technology developed on microfluidic chips in recent years to manipulate small-volume liquids. The other is the dispersed phase. After the continuous phase and the dispersed phase enter the microchannel at the same time, under the action of the microchannel, the dispersed phase is dispersed in a small volume (10 -16 ~10 -11 The form of L) unit is distributed in the continuous phase, forming a series of dispersed micro-droplets. Micro-droplet technology can easily manipulate small-volume droplets. It is widely used in biology, chemistry, materials and other fields, and has broad application prospects. Among them, how to generate micro-droplets conveniently and stably is the key. [0003] At present, most microdroplet generating devices are pl...

AI Technical Summary

Problems solved by technology

Using 3D printing technology to make chips is simple and fast, does not require expensive equipment and environment, and avoids complicated manufacturing steps and relatively high costs. However, it is difficult to discharge uncured printing glue from tiny channels. The size of the produced microchannels is still relatively large, so that the size of the resulting microdroplets is also relatively large, which cannot meet the current needs, which leads to the fact that the 3D printing technology with many advantages cannot be widely used in microfluidic microdroplet chips. preparation

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