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A method for preparing paeonol from plants and its application in the preparation of cosmetics

A technology of paeonol and plants, which is applied in the application field of preparing cosmetics, can solve the problems of poor water solubility, strong volatility, unstable light, temperature and humidity, etc., and achieve strong volatility, specific smell, and convenient product quality control Effect

Active Publication Date: 2021-03-23
GUANGZHOU GIALEN COSMETICS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] And because paeonol has a specific smell, strong volatility, is unstable to light, temperature and humidity, and has poor water solubility, which is not conducive to direct application in medicine and daily chemicals, so it is often processed by inclusion

Method used

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  • A method for preparing paeonol from plants and its application in the preparation of cosmetics
  • A method for preparing paeonol from plants and its application in the preparation of cosmetics
  • A method for preparing paeonol from plants and its application in the preparation of cosmetics

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0053] Embodiment 1: Extract and prepare paeonol from Moutan Cortex

[0054] (1) Extraction of Paeonol

[0055] The cortex of Moutan is used as the raw material, which is cleaned, dried, and crushed into a coarse powder of about 8 meshes. Take 1000g of Moutan cortex coarse powder, add 10 times the amount (10kg) of warm water heated to 60°C, stir and mix well, heat and keep the water temperature at 60°C, soak and extract for 2.5 hours while stirring from time to time, filter while hot under the condition of heat preservation , the filtrate is ready for use; continue to add 8 times the amount (8kg) of warm water heated to 60°C to the filter residue, stir and mix well, heat and keep the water temperature at 60°C, soak and extract for 1.5 hours while stirring from time to time, and filter while hot under the condition of heat preservation , the filtrate is ready for use; continue to add 8 times the amount (8kg) of warm water heated to 60°C to the filter residue, stir and mix well...

Embodiment 2

[0060] Example 2: Extraction and preparation of paeonol from peony pods

[0061] (1) Extraction of Paeonol

[0062] The peony pods are used as raw materials, which are cleaned, dried, and crushed into a coarse powder of about 5 mesh. Take 1000g of peony pod coarse powder, add 10 times the amount (10kg) of warm water heated to 60°C, stir and mix well, heat and keep the water temperature at 60°C, soak and extract for 2.5 hours while stirring from time to time, and keep warm while hot Filtrate, and the filtrate is ready for use; continue to add 8 times the amount (8kg) of warm water heated to 60°C to the filter residue, stir and mix well, heat and keep the water temperature at 60°C, warm soak and extract for 1.5 hours and stir from time to time, and keep warm while hot Filtrate, and the filtrate is ready for use; continue to add 8 times the amount (8kg) of warm water heated to 60°C to the filter residue, stir and mix well, heat and keep the water temperature at 60°C, warm soak a...

Embodiment 3

[0068] Example 3: Extraction and preparation of paeonol from Xu Changqing

[0069] (1) Extraction of Paeonol

[0070] The roots and rhizomes of Xu Changqing are used as raw materials, cleaned, dried, and crushed into coarse powder of about 8 mesh. Take 1500g of cortex moutan coarse powder, add 12 times the amount (18kg) of warm water heated to 65°C, stir and mix well, heat and keep the water temperature at 60°C, extract with ultrasonic (250Hz) for 1.5h, filter while hot under heat preservation conditions, The filtrate is ready for use; continue to add 8 times the amount (12kg) of warm water heated to 60°C to the filter residue, stir and mix well, heat and keep the water temperature at 60°C, extract with ultrasound (250Hz) for 1.0h, and filter while hot under heat preservation conditions, the filtrate Combine with the previous filtrate to obtain the paeonol extract, which is set aside; discard the filter residue.

[0071] (2) Separation of the bold body of paeonol

[0072] T...

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Abstract

The invention discloses a method for preparing paeonol from plants and the application thereof in preparing cosmetics. According to the method, paeonol is prepared through water temperature digestion extraction, so that the content and the activity of the paeonol are extracted and maintained to the maximum extent; as monomer components of the paeonol are refined and purified by using a method of thermal melting cold separation with a low-concentration ethanol solution, not only are impurities effectively removed, but also the conversion rate of the paeonol is high, which is about 98%. The method disclosed by the invention is simple in process procedure, convenient to operate, convenient in product quality control, high in operability, safe and reliable and applicable to industrial production. The prepared paeonol is high in monomer component purity and is firstly dissolved or heated and dissolved into a medicine excipient or a carrier acceptable by cosmetics when being used for preparing the cosmetics, inclusion steps are not needed, and the defects that in the prior art the paeonol has the muddy feeling when being used and active components are hard to absorb by skin can be overcome.

Description

technical field [0001] The invention relates to the fields of plant extracts and cosmetics, in particular to a method for preparing paeonol from plants and its application in preparing cosmetics. Background technique [0002] Paeonol, also known as paeonol, is contained in the peony bark, peony seed coat and peony pods of the Paeoniaceae plant tree peony (Paeoniamoutan Sim.) main active ingredient. Its chemical formula is 2-hydroxy-4-methoxyacetophenone, and its molecular formula is C 9 h 10 o 3 , the relative molecular mass is 166.18. Paeonol is white crystal or crystalline powder with specific smell and slightly spicy taste, easily soluble in ethanol and methanol, soluble in hot water, insoluble in cold water, can volatilize with water vapor, melting point 48℃~51℃. Paeonol has a wide range of pharmacological activities. Studies have shown that paeonol has antibacterial and anti-inflammatory, antipyretic and analgesic, sedative and hypnotic effects, antispasmodic, anti...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C07C45/78C07C49/84C07C45/81A61K8/35A61Q19/02A61Q19/08A61P37/08A61P17/00A61P17/10
CPCA61K8/35A61Q19/02A61Q19/08C07C45/78C07C45/81C07C49/84
Inventor 李吉来傅国华刘少勇郑泽苗刘文丽赵家禾
Owner GUANGZHOU GIALEN COSMETICS