Ultra-trace liquid sample feeding device

A technology of trace liquid and sample injector, which is applied in the field of biochemical experiments, can solve problems such as unsatisfactory, and achieve the effect of improving the utilization rate
CN107199062AActive Publication Date: 2017-09-26FUDAN UNIV

Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
FUDAN UNIV
Publication Date
2017-09-26

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Abstract

The invention belongs to the technical field of biochemical experiments and in particular relates to an ultra-trace liquid sample feeding device. The ultra-trace liquid sample feeding device provided by the invention comprises a capillary tube, a mini-type heat conducting device, a heating source and a trace liquid pump, wherein the inner diameter of the capillary tube is 1 to 10 microns and the outer diameter of the capillary tube is 2 to 20 microns; a liquid inlet is formed in a side wall of the capillary tube; the mini-type heat conducting device is arranged in the capillary tube; the heating source is connected with the mini-type heat conducting device and is used for heating the mini-type heat conducting device; the trace liquid pump is used for pumping ultra-trace liquid into the capillary tube from the liquid inlet. The plurality of capillary tubes can be arranged to form an array sample feeding device. According to the ultra-trace liquid sample feeding device provided by the invention, liquid distribution of the ultra-trace liquid is carried out by utilizing a heat expansion principle of the mini-type heat conducting device, so that picoliter-grade liquid sample distribution is realized. By adopting the ultra-trace liquid sample feeding device, the sample feeding difficulty of the ultra-trace liquid of an existing trace sample feeding device is overcome; picoliter-grade sample feeding can be realized and the utilization rate of a trace valuable sample is improved.
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Description

technical field

[0001] The invention belongs to the technical field of biochemical experiments, and in particular relates to an ultra-micro-volume liquid sampler. Background technique

[0002] At present, the suction range of traditional micro-samplers (pipettes) is generally between 0.1-1000 microliters, which is especially suitable for biological experiments or chemical laboratories. Micro-samplers have been developed to this day, and there are various varieties, such as micro-dispensers, multi-channel micro-samplers, etc. The physical principles of sampling are mainly the following two: ① Use air cushion (also known as piston stroke) Add sample; ②Use the piston without air cushion to add sample.

[0003] In addition, in recent years, a very micro-volume sampler (pipettor) has appeared, and its pipetting method is to use acoustic wave pipetting technology to make the pipette enter the nanoliter pipetting level, but the minimum pipetting volume can only reach 2.5 nanoliter...

Claims

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