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Micropenetrator device for penetrating a biological barrier

A technology of biological barriers and micro-penetrators, applied in the field of micro-penetrator devices for penetrating biological barriers, can solve the problems of needles falling on one side, difficulties, etc.

Active Publication Date: 2017-09-29
XOBADERM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are several inherent problems with this technique, including the extreme difficulty of obtaining a tip that is sharp enough to withstand shear forces so as not to rupture in the skin
Also, the flexibility of the membrane on which the "needles" are placed can cause the needles to fall to one side instead of penetrating the biological barrier

Method used

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  • Micropenetrator device for penetrating a biological barrier
  • Micropenetrator device for penetrating a biological barrier
  • Micropenetrator device for penetrating a biological barrier

Examples

Experimental program
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Embodiment Construction

[0146] Referring to Figure Ia, an apparatus according to an exemplary embodiment of the present invention is presented. The device 2 is presented prior to activation and in contact with the biological barrier 5 . The device 2 includes a flexible substrate 3 with a bio-barrier contact surface 4 . In the presented embodiment, the complementary layer 6 is provided on the opposite second side 8 of the flexible substrate. Presented in this embodiment for clarity are two micropenetrator devices 10 , each micropenetrator device 10 including a head 12 with a first protrusion 14 and a second protrusion 16 . The protrusions extend to the tip 18 and are sharpened to a point in the form presented by cutting each protrusion at an angle that is not perpendicular to the longitudinal length of each protrusion. The head 12 includes an abutment surface 20 that may abut the second side 8 of the flexible substrate 3 . In the embodiment presented, the header 12 is encapsulated within the layer ...

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Abstract

The invention discloses a micropenetrator device for penetrating a biological barrier. The present application relates to a device (2) that may be placed on a biological barrier (5) that can be used to perforate the biological barrier for a variety of purposes such as cosmetic, scar treatment or for the delivery of active agents. According to one aspect, there is a flexible substrate (3) having a first side and a second opposing side and a plurality of micro-penetrator (10) arrangements each comprising a head (12) and a first and second projection (14, 16) for penetrating a biological barrier extending from the head. The first and second projection at least partially extends through the flexible substrate towards the first side. The head comprises an elongate arm (26) for spacing apart the first and second projections. A force is applied to the second side causing flexing of the flexible substrate and pushing the projections into communication with a biological barrier.

Description

technical field [0001] The present invention relates to a device that can be placed on a biological barrier, such as the stratum corneum, which can then be used to perforate the biological barrier for various purposes, such as cosmetic, scar treatment or for delivery of active agents for systemic or Topical treatment or vaccination. Background technique [0002] Microneedling has been an interesting research topic for many years in the field of transdermal drug delivery and in aesthetic dermatology. The first microneedling products have appeared in this aesthetic field. The treatment of rolling over the skin using a device such as a barrel with microneedles extending therefrom is now being offered in salons and clinics around the world and has been used for the treatment of scars, stretch marks and wrinkles. Microneedling has various advantages over lasers and other cosmetic treatments, especially the much cheaper microneedling devices. Microneedles have been used in stud...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M37/00
CPCA61M37/0015A61M2037/0053A61M2037/0046A61M2037/0023A61M2037/003A61B2017/00747A61B17/205A61M2037/0061
Inventor 安德鲁·詹姆斯·柯比
Owner XOBADERM
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