Application of dimetridazole as internal standard substance to hydrogen nuclear magnetic resonance technology

Abstract

The invention discloses application of dimetridazole as an internal standard substance to a hydrogen nuclear magnetic resonance technology. The application of the dimetridazole as the internal standard substance to the hydrogen nuclear magnetic resonance technology is characterized by comprising at least one of 1), 2) and 3), wherein 1) structural analysis on to-be-measured compound; 2) qualitative analysis on to-be-measured compound; 3) quantitative analysis on to-be-measured compound. The application of the dimetridazole as the internal standard substance to the hydrogen nuclear magnetic resonance technology has the benefits that the high-purity dimetridazole is adopted as the internal standard substance, is simple in hydrogen spectrum and wider in quantitative peak range, can be dissolved in various deuterium reagents and has the advantage of traceability.

Description

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AI Technical Summary

Benefits of technology

This patented method allows for accurate determination of an unknown substance's content by measuring absorption spectra from different samples with various types of dialkyl azodicarboximide (DDAC) or other solvents that are used instead of DMSO. By comparing these spectral data against known standards, this technology provides reliable results even when analyzing complex mixtures containing many components.

Problems solved by technology

This patents describes methods for analyzing certain materials such as dimethylpyrazine (DM) or other small molecules called didemetonitrochelones. These techniques involve measuring their properties under specific experimental condition at temperatures between 20-40°C. They require pure samples containing these components because they cannot exist alone without them mixed together due to similar physical attributes like solvation behavior. However, it may happen when some ingredients have poor quality control during production processes. To address this issue, several new classes of chromane sulfonic acids were developed which could replace existing ones.

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