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Externally applied Chinese medicinal composition for relieving eye fatigue

A technology of composition and traditional Chinese medicine, which is applied in the direction of drug combination, drug delivery, active ingredients of hydroxyl compounds, etc., and can solve problems such as intolerance and irritation

Inactive Publication Date: 2017-12-26
陕西新视明医药生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] People often relieve and treat eye fatigue by eye drops, but the way of direct contact with the cornea may cause some people intolerance and even irritation due to the irritating ingredients in the eye drops
Massage can also relieve eye fatigue, but generally it can only provide temporary relief

Method used

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  • Externally applied Chinese medicinal composition for relieving eye fatigue
  • Externally applied Chinese medicinal composition for relieving eye fatigue
  • Externally applied Chinese medicinal composition for relieving eye fatigue

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Raw materials: 44g of chrysanthemum, 28g of salvia miltiorrhiza, 38g of cortex cortex, 48g of peony bark, 15g of pearl powder, 3g of menthol, 1.5g of borneol;

[0023] Excipients: β-cyclodextrin 18g, xanthan gum 5g, glycerin 61g, potassium sorbate 6g;

[0024] Preparation method: take the above seven herbs, take chrysanthemum, salvia miltiorrhiza, cortex cortex, and peony bark, add water to decoct twice, filter, concentrate the filtrate to a relative density of 1.05-1.10 (40°C), cool to room temperature, add an appropriate amount of ethanol to make the alcohol content reach 50%, refrigerated at 4°C for 12 hours, filtered, recovered ethanol to obtain the extract, and set aside; take pearl powder, add 25% lactic acid, stir well, stir once every half hour, keep warm and hydrolyze twice at 65°C, 3 hours each time, filter, the filtrate is pearl hydrolyzate for later use; borneol and menthol use beta cyclodextrin (borneol, menthol: β-CD=1:8, β-CD (g): water (ml) =1:10, using...

Embodiment 2

[0027] Chrysanthemum 42g, Salvia 35g, Phellodendron 34g, Moutan bark 55g, pearl powder 12g, menthol 3.3g, borneol 1.4g;

[0028] Preparation method: take the above seven herbs, take chrysanthemum, salvia miltiorrhiza, Phellodendron cortex, Moutan cortex and add 50% ethanol to reflux 2-3 times, filter, combine the extracts, recover the ethanol to obtain the extract extract, and set aside; pearl powder hydrolyzate and clathrate The preparation of the product is the same as in Example 1; the above extract extract is mixed with pearl hydrolyzate, beta-cyclodextrin inclusion complex, xanthan gum, glycerin, behenitol A and other auxiliary materials, and coated on non-woven fabrics to prepare into eye stickers.

Embodiment 3

[0030] Chrysanthemum 50g, Salvia miltiorrhiza 25g, Phellodendron 42g, Moutan bark 45g, pearl powder 18g, menthol 2.5g, borneol 1.6g;

[0031] Preparation method: Take the above seven herbs, take chrysanthemum, salvia, cortex cortex, peony bark and add 70% ethanol to ultrasonically extract 2 to 3 times, combine the extracts, filter, concentrate the filtrate, centrifuge at 3000r / min for 15min, take the supernatant, concentrate into an extractum, for subsequent use; the preparation of the pearl powder hydrolyzate and the inclusion compound is the same as in Example 1; Evenly, spread on non-woven fabric to make eye patches.

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Abstract

The invention relates to an externally applied Chinese medicinal composition for relieving eye fatigue. The composition comprises the following bulk drugs: chrysanthemum, Salvia miltiorrhiza, phellodendron, cortex moutan, pearl powder, menthol, and borneol. The Chinese medicinal composition provided by the invention has a total improvement rate on eye fatigue up to 88.89%, which is significantly higher than the 33.33% of a placebo group, can keep the eye moist, and has a significant mitigation effect on eye dryness, scorching hot feel, frequent blinking, eye itching, non-sustainable reading, heavy eyes, eye stinging, reflex headache, diplopia, double vision, easy line skip, foggy view, phengophobia, lacrimation, acid and swollen symptoms.

Description

technical field [0001] The invention relates to an externally used traditional Chinese medicine composition for relieving eye fatigue, which belongs to the field of traditional Chinese medicine health care. Background technique [0002] Eye fatigue is a common disease in ophthalmology. The dry eyes, astringent eyes, sore eyes, blurred vision and even vision loss caused by it directly affect people's work and life. Eye fatigue is mainly caused by people staring at the computer or TV screen for a long time, the decrease in the number of blinks leads to a corresponding decrease in tear secretion, and at the same time, the flickering screen strongly stimulates the eyes. kind of eye disease. [0003] People often relieve and treat eye fatigue by eye drops, but the way of direct contact with the cornea may cause some people intolerance or even irritation due to the stimulating ingredients in the eye drops. Massage can also relieve eye fatigue, but generally it can only provide t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/756A61P27/02A61K35/618A61K31/045
CPCA61K9/0014A61K9/0048A61K31/045A61K35/618A61K36/287A61K36/537A61K36/65A61K36/71A61K36/756A61K2300/00
Inventor 张超峰
Owner 陕西新视明医药生物科技有限公司
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