Medicine composition for treating gestational hypertension complicated with preeclampsia
A technology for gestational hypertension and preeclampsia, applied in the field of medicine, can solve problems such as unfavorable patients, blood pressure control, slow onset of effect, etc., and achieve the effects of avoiding adverse reactions, improving antihypertensive effect, and reducing urinary protein.
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Embodiment 1
[0041] Example 1 Oral solution for treating pregnancy-induced hypertension complicated with preeclampsia and its preparation process
[0042] The following is the composition and preparation process of the oral liquid for treating gestational hypertension complicated with preeclampsia.
[0043] 1. Drug prescription
[0044]
[0045] Second, the preparation process:
[0046] (1) Pulverization: Take the prescription amount of medlar, chrysanthemum, Rehmannia glutinosa, wine cornus, Moutan cortex, Chinese yam, Poria cocos, Alisma, and Leiwan, and pulverize them separately, pass through a 40-mesh sieve, and mix to obtain medicinal powder;
[0047] (2) Extraction: add water to the powder obtained in step (1) and decoct twice, add water 6 times the weight of the medicinal powder for the first time and decoct for 6 hours, add water 4 times the weight of the medicinal powder for the second time and decoct for 2 hours, Combine the water decoction and let it cool down;
[0048] (3...
Embodiment 2
[0051] Example 2 Oral granules for treating gestational hypertension complicated with preeclampsia and its preparation process
[0052] The following are the prescription and preparation process of oral granules for treating pregnancy-induced hypertension complicated with preeclampsia.
[0053] 1. Drug prescription
[0054]
[0055] Second, the preparation process:
[0056] (1) Pulverization: Take the prescription amount of medlar, chrysanthemum, Rehmannia glutinosa, wine cornus, Moutan cortex, Chinese yam, Poria cocos, Alisma, and Leiwan, and pulverize them separately, pass through a 40-mesh sieve, and mix to obtain medicinal powder;
[0057] (2) Extraction: add water to the powder obtained in step (1) and decoct twice, add water 6 times the weight of the medicinal powder for the first time and decoct for 6 hours, add water 4 times the weight of the medicinal powder for the second time and decoct for 2 hours, Combine the water decoction and let it cool down;
[0058] (3...
Embodiment 3
[0061] Embodiment 3 Pharmacodynamics study in vivo
[0062] 1. Drugs and their preparation
[0063] 1. Experimental drug: the clear ointment of prescription 1-3 in the embodiment 1 is selected for the experimental drug.
[0064] Comparing drugs:
[0065] Comparative drug 1 and comparative drug 2 were prepared respectively according to the following prescriptions.
[0066]
[0067] The preparation process of contrast drug 1 is as follows:
[0068] (1) Pulverization: Take the prescription amount of medlar, chrysanthemum, Rehmannia glutinosa, wine cornel, Moutan cortex, Chinese yam, Poria cocos, and Alisma chinensis, respectively pulverize, pass through a 40-mesh sieve, and mix to obtain medicinal material powder;
[0069] (2) Extraction: add water to the powder obtained in step (1) and decoct twice, add water 6 times the weight of the medicinal powder for the first time and decoct for 6 hours, add water 4 times the weight of the medicinal powder for the second time and dec...
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